人的腕关节是一种优雅的机制。手腕允许将手定位和定向到前臂。人手的计算建模,尤其是腕关节,可以揭示有关生物力学机制的重要信息,并为其功能障碍和病理提供依据。例如,这可用于全腕关节置换术(TWA)的治疗计划.在这项研究中,提出了肌肉骨骼建模的不同优化方法和解剖参数的敏感性分析。优化包括找到目标函数的最佳可用值,包括各种不同类型的目标函数。在最简单的情况下,优化包括通过系统地从允许的集合中选择输入值并计算函数的值来最大化或最小化函数。优化技术用于许多方面,例如关节或关节系统如手腕的模型构建。本研究的目的是显示建模所包含信息的可变性和影响,研究代表性场景中关节的生物力学功能和载荷情况。通过优化将它们考虑在内的这些可能性对于将计算建模应用于关节病理学至关重要。
The human wrist joint is an elegant mechanism. The wrist allows the positioning and orienting of the hand to the forearm. The computational modeling of the human hand, especially of the wrist joint, can reveal important information about biomechanical mechanisms and provide the basis for its dysfunction and pathologies. For instance, this could be used for therapy planning in total wrist arthroplasty (TWA). In this study, different optimization methods and sensitivity analyses of anatomical parameters for musculoskeletal modeling were presented. Optimization includes finding the best available value of an objective function, including a variety of different types of objective functions. In the simplest
case, optimization consists of maximizing or minimizing a function by systematically choosing input values from within an allowed set and computing the value of the function. Optimization techniques are used in many facets, such as the model building of joints or joint systems such as the wrist. The purpose of this study is to show the variability and influence of the included information for modeling, investigating the biomechanical function and load situation of the joint in representative scenarios. These possibilities to take them into account by an optimization and seem essential for the application of computational modeling to joint pathologies.