Thoracic Vertebrae

胸椎
  • 文章类型: Journal Article
    "小儿胸腰椎外伤,虽然罕见,是发病和死亡的重要原因,需要早期,准确的诊断和管理。“在儿科人群中获得详细的病史和体格检查可能很困难。因此,先进成像的门槛,比如磁共振成像,低,应在头部受伤的患者中进行,精神状态改变,无法配合考试,以及涉及1根以上脊柱的骨折。“小儿胸腰椎创伤的分类主要基于成人研究,几乎没有高水平的证据来检验小儿人群的有效性和准确性。“在确定是否进行手术管理时,患者的损伤模式和神经系统状况是最重要的因素。
    » Pediatric thoracolumbar trauma, though rare, is an important cause of morbidity and mortality and necessitates early, accurate diagnosis and management.» Obtaining a detailed history and physical examination in the pediatric population can be difficult. Therefore, the threshold for advanced imaging, such as magnetic resonance imaging, is low and should be performed in patients with head injuries, altered mental status, inability to cooperate with examination, and fractures involving more than 1 column of the spine.» The classification of pediatric thoracolumbar trauma is based primarily on adult studies and there is little high-level evidence examining validity and accuracy in pediatric populations.» Injury pattern and neurologic status of the patient are the most important factors when determining whether to proceed with operative management.
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  • 文章类型: Systematic Review
    开放前路和开放后路的手术结果,对于胸腰椎A3至C3/AO型骨折,比较。
    1990年至2024年进行了PubMed搜索,涉及前牙,后路和联合入路。纳入标准:新鲜创伤性T10至L2骨折,年龄≥13岁,≥10例,最少随访6个月。排除标准:尸体研究,病理性骨折,reviews,胸腔镜辅助,微型开放外侧(MOLA)和微创前或后入路。Coleman方法学评分(CMS)(针对脊柱创伤进行了修改)表明了所选研究中的潜在选择偏差。PRISMA指南进行了调整。
    选择了847名参与者的19项研究。CMS的平均质量评分是公平的。前路,虽然它能更好地减压受损的椎管,与后入路相比,它还与手术并发症增加有关。神经系统的结果,校正损失和再操作率,这两种方法都相似。本系统综述支持后路入路。
    与后路相比,前路入路要求苛刻,并且手术并发症发生率更高。所选研究的局限性包括:1)方法选择,2)骨折类型和神经状态的分类以及3)使用的各种仪器。
    CRD42023484222。
    UNASSIGNED: Surgical outcomes of open anterior and open posterior approaches, for thoracolumbar A3 to C3/AO type fractures, are compared.
    UNASSIGNED: A PubMed search was conducted from 1990 to 2024 related to anterior, posterior, and combined approaches. Inclusion criteria: Fresh traumatic T10 to L2 fractures, age ≥13 years, ≥10 cases, minimum follow-up 6 months. Exclusion criteria: Cadaveric studies, pathological fractures, reviews, thoracoscopy-assisted, mini-open lateral (MOLA) and minimal invasive anterior or posterior approaches. Coleman Methodology Scores (CMS) (modified for spinal trauma) indicated potential selection bias in the selected studies. PRISMA guidelines were adapted.
    UNASSIGNED: Nineteen studies with 847 participants were selected. The average CMS quality score was fair. The anterior approach, although it better decompresses the compromised spinal canal, it is also associated with increased surgical complications compared to the posterior approach. The neurological outcome, the loss of correction and the reoperation rate, were similar to both approaches. This systematic review favors posterior approach.
    UNASSIGNED: The anterior approach is demanding and is associated with a higher rate of surgical complications compared to the posterior approach. The limitations of the selected studies included inconsistence in the: 1) approaches selection, 2) classifications of the fracture types and the neurological status and 3) variety of instrumentations used.
    UNASSIGNED: CRD42023484222.
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  • 文章类型: Journal Article
    评估不使用侵入性手术的物理疗法(PT)缓解有症状的胸神经根病(TR)的疗效。从成立到2023年1月27日,由经验丰富的医学图书馆员在EBSCOCINAHL进行数据库搜索,OvidCochrane中央控制试验登记册,OvidEmbase,OvidMEDLINE,Scopus,和WebofScience核心合集。纳入标准包括涉及成年患者(年龄≥18岁)的研究,这些患者具有磁共振成像证实的TR并接受了结构化,任何长度的监督PT程序。包括所有类型的研究。使用国家心脏评估研究质量和偏倚风险,肺,和血液研究所(NHLBI)研究质量评估工具。使用建议分级评估来评估证据的确定性,发展,和评估(等级)方法。未进行荟萃分析。总共筛选了1,491项研究,其中7项研究符合纳入标准,5个案例研究和2个队列研究。所有研究均显示PT对TR的改善或消退。在大多数研究中没有注意到定量改善,对PT方案的描述很少。总体质量评估表明,3项研究表现良好,“1”公平,“和3”质量差的证据。由于存在偏见的风险,证据的确定性“低”。专门的PT计划可能有助于缓解有症状的TR;但是由于证据有限,偏见的风险,证据的确定性低,数据太弱,无法支持明确的结论。
    To evaluate the efficacy of physical therapy (PT) to alleviate symptomatic thoracic radiculopathy (TR) without the use of invasive procedures. Database search was conducted by an experienced medical librarian from inception until January 27, 2023, in EBSCO CINAHL with Full Text, Ovid Cochrane Central Register of Controlled Trials, Ovid Embase, Ovid MEDLINE, Scopus, and Web of Science Core Collection. Inclusion criteria included studies that involved adult patients (age≥18) who had a magnetic resonance imaging-confirmed TR and underwent a structured, supervised PT program of any length. All types of studies were included. Study quality and risk of bias were assessed using the National Heart, Lung, and Blood Institute (NHLBI) Study Quality of Assessment Tool. Certainty in evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. A meta-analysis was not performed. A total of 1,491 studies were screened and 7 studies met inclusion criteria, 5 case studies and 2 cohort studies. All studies showed improvement or resolution of the TR with PT. Quantitative improvements were not noted in most studies and PT regimens were sparsely described. Overall quality assessment demonstrated 3 studies had \"good,\" 1 \"fair,\" and 3 \"poor\" quality evidence. Certainty of evidence was \"low\" due to risk of bias. A dedicated PT program may help to alleviate symptomatic TR; however due to limited evidence, risk of bias, and low certainty in evidence, the data is too weak to support a definite conclusion.
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  • 文章类型: Meta-Analysis
    目的:分析青少年特发性脊柱侧凸(AIS)矫正手术后发生近端交界性脊柱后凸(PJK)的危险因素。
    方法:PubMed,Medline,Embase,科克伦图书馆,WebofScience,CNKI,和EMCC数据库被搜索的回顾性研究利用所有AIS患者PJK矫正手术后收集术前,术后,和后续成像参数,包括胸椎后凸(TK),腰椎前凸(LL),近端连接角(PJA),矢状垂直轴(SVA),骨盆发病率(PI),骨盆倾斜(PT),骨盆发病率-腰椎前凸(PI-LL),骶骨斜坡(SS),杆轮廓角度(RCA)和上器械椎骨(UIV)。
    结果:本荟萃分析包括19项回顾性研究,其中干预组550例,对照组3456例。总的来说,性别(OR1.40,95%CI(1.08,1.83),P=0.01),术前TK较大(WMD6.82,95%CI(5.48,8.16),P<0.00001),较大的随访TK(WMD8.96,95%CI(5.62,12.30),P<0.00001),术后LL较大(WMD2.31,95%CI(0.91,3.71),P=0.001),较大的随访LL(WMD2.51,95%CI(1.19,3.84),P=0.0002),LL(WMD-2.72,95%CI(-4.69,-0.76),P=0.006),术后PJA较大(WMD4.94,95%CI(3.62,6.26),P<0.00001),更大的随访PJA(WMD13.39,95%CI(11.09,15.69),P<0.00001),术后PI-LL较大(WMD-9.57,95%CI(-17.42,-1.71),P=0.02),更大的随访PI-LL(WMD-12.62,95%CI(-17.62,-7.62),P<0.00001),术前SVA较大(WMD0.73,95%CI(0.26,1.19),P=0.002),术前SS较大(WMD-3.43,95%CI(-4.71,-2.14),P<0.00001),RCA(大规模杀伤性武器1.66,95%CI(0.48,2.84),P=0.006)被确定为AIS患者PJK的危险因素。对于Lenke5AIS患者,术前TK较大(WMD7.85,95%CI(5.69,10.00),P<0.00001),术后TK较大(WMD9.66,95%CI(1.06,18.26),P=0.03,随访TK较大(WMD11.92,95%CI(6.99,16.86),P<0.00001,术前PJA较大(WMD0.72,95%CI(0.03,1.41),P=0.04,术后PJA较大(WMD5.54,95%CI(3.57,7.52),P<0.00001),更大的随访PJA(WMD12.42,95%CI9.24,15.60),P<0.00001,随访SVA较大(WMD0.07,95%CI(-0.46,0.60),P=0.04),术前PT较大(WMD-3.04,95%CI(-5.27,-0.81),P=0.008,更大的随访PT(WMD-3.69,95%CI(-6.66,-0.72),P=0.02)被确定为PJK的危险因素。
    结论:矫正手术后,19%的AIS患者经历过PJK,Lenke5贡献了25%。术前和术后测量在预测PJK发生方面起着重要作用;因此,一丝不苟,个性化的术前计划至关重要。这包括考虑基于Lenke分类的个性化治疗作为我们未来的评估标准。
    OBJECTIVE: To analyze the risk factors of proximal junctional kyphosis (PJK) after correction surgery in patients with adolescent idiopathic scoliosis (AIS).
    METHODS: PubMed, Medline, Embase, Cochrane Library, Web of Science, CNKI, and EMCC databases were searched for retrospective studies utilizing all AIS patients with PJK after corrective surgery to collect preoperative, postoperative, and follow-up imaging parameters, including thoracic kyphosis (TK), lumbar lordosis (LL), proximal junctional angle (PJA), the sagittal vertical axis (SVA), pelvic incidence (PI), pelvic tilt (PT), pelvic incidence-lumbar lordosis (PI-LL), sacral slope (SS), rod contour angle (RCA) and upper instrumented vertebra (UIV).
    RESULTS: Nineteen retrospective studies were included in this meta-analysis, including 550 patients in the intervention group and 3456 patients in the control group. Overall, sex (OR 1.40, 95% CI (1.08, 1.83), P = 0.01), larger preoperative TK (WMD 6.82, 95% CI (5.48, 8.16), P < 0.00001), larger follow-up TK (WMD 8.96, 95% CI (5.62, 12.30), P < 0.00001), larger postoperative LL (WMD 2.31, 95% CI (0.91, 3.71), P = 0.001), larger follow-up LL (WMD 2.51, 95% CI (1.19, 3.84), P = 0.0002), great change in LL (WMD - 2.72, 95% CI (- 4.69, - 0.76), P = 0.006), larger postoperative PJA (WMD 4.94, 95% CI (3.62, 6.26), P < 0.00001), larger follow-up PJA (WMD 13.39, 95% CI (11.09, 15.69), P < 0.00001), larger postoperative PI-LL (WMD - 9.57, 95% CI (- 17.42, - 1.71), P = 0.02), larger follow-up PI-LL (WMD - 12.62, 95% CI (- 17.62, - 7.62), P < 0.00001), larger preoperative SVA (WMD 0.73, 95% CI (0.26, 1.19), P = 0.002), larger preoperative SS (WMD - 3.43, 95% CI (- 4.71, - 2.14), P < 0.00001), RCA (WMD 1.66, 95% CI (0.48, 2.84), P = 0.006) were identified as risk factors for PJK in patients with AIS. For patients with Lenke 5 AIS, larger preoperative TK (WMD 7.85, 95% CI (5.69, 10.00), P < 0.00001), larger postoperative TK (WMD 9.66, 95% CI (1.06, 18.26), P = 0.03, larger follow-up TK (WMD 11.92, 95% CI (6.99, 16.86), P < 0.00001, larger preoperative PJA (WMD 0.72, 95% CI (0.03, 1.41), P = 0.04, larger postoperative PJA (WMD 5.54, 95% CI (3.57, 7.52), P < 0.00001), larger follow-up PJA (WMD 12.42, 95% CI 9.24, 15.60), P < 0.00001, larger follow-up SVA (WMD 0.07, 95% CI (- 0.46, 0.60), P = 0.04), larger preoperative PT (WMD - 3.04, 95% CI (- 5.27, - 0.81), P = 0.008, larger follow-up PT (WMD - 3.69, 95% CI (- 6.66, - 0.72), P = 0.02) were identified as risk factors for PJK.
    CONCLUSIONS: Following corrective surgery, 19% of AIS patients experienced PJK, with Lenke 5 contributing to 25%. Prior and post-op measurements play significant roles in predicting PJK occurrence; thus, meticulous, personalized preoperative planning is crucial. This includes considering individualized treatments based on the Lenke classification as our future evaluation standard.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Systematic Review
    背景:神经鞘瘤是良性周围神经鞘瘤,由髓鞘化雪旺细胞引起。尽管在前庭神经肿瘤等神经鞘瘤变体中经常遇到大囊性变化,它们在脊柱肿瘤中极为罕见。
    方法:4个数据库的病例报告和系统评价(OvidMedline,PubMed,科学直接,和SCOPUS)从开始到现在。包括所有报告硬膜内囊性胸神经鞘瘤的同行评审出版物。
    结果:我们确定了8篇文献,记录了9例囊性胸椎神经鞘瘤。四个是女性,5名男性;平均年龄41岁(范围,27-80).表现从偶然到疼痛,感官变化,下肢轻瘫,或肠/膀胱功能障碍。特征性影像学检查结果包括T1低信号,T2高强度,和脐带脱落或压迫。本病例遵循类似的模式:一名52岁男性表现为双侧下肢无力恶化,腰痛,步态功能障碍,恶化超过3天。检查还显示左下肢感觉降低。影像学识别出良好的硬膜内,在T7-T10上延伸的髓外巨囊。患者接受了椎板切除术,导致肿瘤完全切除并恢复了完整的神经功能。最终病理证实为良性囊性神经鞘瘤。
    结论:胸椎神经鞘瘤极为罕见,缺乏对其自然史和发病机制进行临床分类的综合方案。我们报告了第10例这种神经鞘瘤,和第一次相关的系统审查。虽然大囊性胸椎神经鞘瘤并不常见,准确的诊断和适当的神经外科治疗对这些脆弱的患者至关重要,考虑到神经外科治疗后获得出色功能结局的机会。
    Schwannomas are benign peripheral nerve sheath tumors arising from myelinating Schwann cells. Although macrocystic changes are regularly encountered in schwannoma variants such as vestibular nerve tumors, they are exceedingly rare among spinal neoplasms.
    Case report and systematic review of 4 databases (Ovid Medline, PubMed, Science Direct, and SCOPUS) from inception to present. All peer-reviewed publications reporting intradural cystic thoracic schwannoma were included.
    We identified 8 publications documenting 9 cases of cystic thoracic schwannoma. Four were female, 5 male; median age was 41 years (range, 27-80). Presentations ranged from incidental to pain, sensory changes, lower extremity paresis, or bowel/bladder dysfunction. Characteristic radiographic findings included T1 hypointensity, T2 hyperintensity, and cord effacement or compression. The present case followed a similar pattern: a 52-year-old male presented with worsening bilateral lower extremity weakness, low back pain, and gait dysfunction, worsening over 3 days. Examination also revealed decreased left lower extremity sensation. Imaging identified a well-delineated intradural, extramedullary macrocystic extending over T7-T10. The patient underwent a laminectomy resulting in complete tumor resection and restoration of intact neurologic function. Final pathology confirmed benign cystic schwannoma.
    Macrocystic thoracic schwannomas are exceedingly rare and lack a comprehensive scheme for clinical classification of their natural history and pathogenesis. We report the 10th case of such a schwannoma, and the first associated systematic review. Although macrocystic thoracic schwannomas are not frequently encountered, accurate diagnosis and appropriate neurosurgical treatment is critical in these vulnerable patients, given the opportunity for excellent functional outcomes following neurosurgical treatment.
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  • 文章类型: Journal Article
    目的:比较后路椎弓根螺钉内固定直接和间接减压治疗胸腰椎爆裂骨折的安全性和有效性。
    方法:本研究是在PRISMA声明的基础上进行的。我们系统地搜索了截至2023年7月3日的PubMed和Embase数据库。招募了比较间接减压和直接减压的相关研究。加权平均差(WMD),分析了连续和二分数据的优势比(OR)和95%置信区间(CI),分别。P<0.05被认为具有统计学意义。
    结果:手术时间(WMD:-37.14,95%CI:[-42.64,31.64],P<0.00001,I2=0%)和术中失血量(WMD:-316.82,95%CI:[-469.80,-163.85],P<0.0001,I2=99%)间接减压组显著降低。椎体前高度百分比(WMD:3.98,95%CI:[2.36,5.60],P<0.00001,I2=32%)和椎管的侵占率(WMD:1.48,95%CI:[0.56,2.40],P=0.002,I2=35%)间接减压组明显高于对照组。在神经系统恢复和Cobb角的等级中没有发现统计学差异。
    结论:在后纵韧带完整的情况下,间接减压的后路椎弓根螺钉内固定治疗有或无神经功能缺损的胸腰椎爆裂骨折是安全有效的。
    To compare the safety and efficacy between posterior pedicle screw fixation with direct versus indirect decompression in treating patients with thoracolumbar burst fracture.
    This study was conducted on the basis of PRISMA statement. We systematically searched the PubMed and Embase databases up to July 3, 2023. Relevant studies comparing indirect decompression and direct decompression were recruited. Weighted mean differences (WMDs), odds ratios (ORs) and 95% confidence intervals (CIs) were analyzed for continuous and dichotomous data, respectively. P < 0.05 was considered statistically significant.
    The operation time (WMD: -37.14, 95% CI: [-42.64, 31.64], P < 0.00001, I2 = 0%) and intraoperative blood loss (WMD: -316.82, 95% CI: [-469.80, -163.85], P < 0.0001, I2 = 99%) of indirect decompression group were significantly lower. Percentage of anterior vertebral body height (WMD: 3.98, 95% CI: [2.36, 5.60], P < 0.00001, I2 = 32%) and encroachment rate of the spinal canal (WMD: 1.48, 95% CI: [0.56, 2.40], P = 0.002, I2 = 35%) of indirect decompression group were significantly higher. No statistical difference was identified in grades of neurologic recovery and Cobb angle.
    Posterior pedicle screw fixation with indirect decompression was safe and effective for thoracolumbar burst fracture with or without neurologic deficits when posterior longitudinal ligament was intact.
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  • 文章类型: Journal Article
    背景:颈部和胸部推力或非推力操作已证明对颈部疼痛患者有效,但缺乏对颈部疼痛患者的两种干预措施进行比较的研究.
    目的:探讨颈椎推力或非推力手法与胸或颈胸手法相比改善疼痛的效果,残疾,和颈部疼痛患者的活动范围。
    方法:系统评价和荟萃分析。
    方法:在PubMed中进行搜索,PEDro,科克伦图书馆,CINHAL,和WebofScience数据库从成立到2023年5月22日。包括将颈椎推力或非推力操作与胸或颈胸操作进行比较的随机临床试验。用PEDro量表评估方法学质量,并使用GRADE指南评估证据的确定性。
    结果:纳入6项研究。荟萃分析显示,颈椎推力或非推力操作与胸或颈胸操作之间的疼痛强度没有差异。残疾,或颈椎在任何平面上的运动范围。疼痛强度的证据确定性被降级为非常低,残疾为中度或非常低,颈椎活动范围为低或非常低。
    结论:有中度到极低的确定性证据表明,颈椎推挤或非推挤手法与胸或颈胸手法在改善疼痛方面的有效性没有差异,残疾,和颈部疼痛患者的活动范围。
    CRD42023429933。
    Cervical and thoracic thrust or non-thrust manipulations have shown to be effective in patients with neck pain, but there is a lack of studies comparing both interventions in patients with neck pain.
    To investigate the effects of cervical thrust or non-thrust manipulations compared to thoracic or cervicothoracic manipulations for improving pain, disability, and range of motion in patients with neck pain.
    Systematic review and meta-analysis.
    Searches were performed in PubMed, PEDro, Cochrane Library, CINHAL, and Web of Science databases from inception to May 22, 2023. Randomized clinical trials comparing cervical thrust or non-thrust manipulations to thoracic or cervicothoracic manipulations were included. Methodological quality was assessed with PEDro scale, and the certainty of evidence was evaluated using GRADE guidelines.
    Six studies were included. Meta-analyses revealed no differences between cervical thrust or non-thrust manipulations and thoracic or cervicothoracic manipulations in pain intensity, disability, or cervical range of motion in any plane. The certainty of evidence was downgraded to very low for pain intensity, to moderate or very low for disability and to low or very low for cervical range of motion.
    There is moderate to very low certainty evidence that there is no difference in effectiveness between cervical thrust or non-thrust manipulations and thoracic or cervicothoracic manipulations for improving pain, disability, and range of motion in patients with neck pain.
    CRD42023429933.
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  • 文章类型: Case Reports
    目的:毛细血管瘤是罕见的血管病变,很少影响中枢神经系统。当它们出现在椎管内时,它们通常被限制在内部,很少有髓内延伸。我们在此介绍一例罕见的脊髓髓内毛细血管瘤,并对文献进行了系统的回顾。
    方法:使用健康记录软件EPIC和放射学管理软件系统RIS/PACS(QReads)对病历和影像学资料进行回顾性审查。该报告是根据援外社准则编写的。我们还对所有脊髓内毛细血管血管瘤的病例进行了系统的文献回顾,按照PRISMA准则。
    结果:这是一例54岁男性,表现为下肢进行性截瘫和感觉障碍。脊柱MRI显示以T11为中心的髓内增强病变,并伴有脊髓压迫。他接受了胸椎椎板切除术和病灶的全切,没有并发症,随后神经系统检查有所改善。组织学检查显示发现与毛细血管血管瘤一致。文献综述还记录了21项研究,总共38例髓内毛细血管瘤。
    结论:单纯髓内毛细血管血管瘤是一种罕见的脊柱病变,文献报道仅有少数病例。这在髓内肿瘤的鉴别诊断中应该考虑。手术治疗仍然是有症状患者的一线治疗。
    Capillary hemangiomas are rare vascular lesions that rarely affect the central nervous system. When they present within the spinal canal, they are typically confined intradurally, with intramedullary extension rare. We present a rare case of spinal intramedullary capillary hemangioma, with a systematic review of the literature.
    Medical records and imaging data were retrospectively reviewed using the health record software EPIC (Verona, Wisconsin, USA) and the radiology management software system RIS/PACS (Radiology Information System/Picture Archiving and Communication System; QREADS). The report was written in accordance with the CARE (case reports) guidelines. We also performed a systematic review of the literature on all cases of intramedullary spinal capillary hemangiomas in accordance with PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines.
    We report a case of a 54-year-old man who presented with progressive paraplegia and sensory deficits in the lower extremities. Spinal magnetic resonance imaging showed an intramedullary enhancing lesion centered at T11 with associated spinal cord compression. He underwent thoracic laminectomy and gross total resection of the lesion without complications and subsequent improvement on his neurological examination. Histological examination showed findings consistent with a capillary hemangioma. The literature review also documented 21 studies with a combined total of 38 cases of intramedullary spinal capillary hemangioma.
    Purely intramedullary capillary hemangiomas are unusual spinal lesions with only a few cases reported in the literature. These should be considered in the differential diagnosis of intramedullary tumors. Surgical management remains the first line of treatment for symptomatic patients.
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  • 文章类型: Systematic Review
    目标:尽管垂直层状骨折(VLF)通常被认为是胸腰椎骨折(TLFs)的严重程度标志,它在决策中的确切作用从未确立。本范围综述旨在对VLF在TLF决策中的作用进行综合研究。
    方法:按照PRISMA指南进行系统评价。我们搜索了PubMed,Scopus,和WebofScience从成立到2023年6月11日,用于研究VLF在胸腰椎骨折与硬脑膜撕裂中的关联,神经功能缺损,射线照相参数,或治疗结果。此外,包括分析VLF爆裂骨折生物力学的实验研究。这些研究提取了关键发现,目标,和患者人群。对VLF与硬脑膜裂伤和神经功能缺损的关系进行了荟萃分析,和OR以95%置信区间(CI)合并。
    结果:本系统综述包括28项研究,涵盖2021名患者,12例纳入荟萃分析.根据研究的主要主题,VLF与硬脑膜裂伤的关联(n=14),神经功能缺损(n=4),射线照相参数(n=3),胸腰椎骨折分类(n=2),和治疗结果(n=2)。7项研究共1010例患者报告VLF与神经功能缺损之间存在显著关联(OR=7.35,95%CI[3.97,14.25];P<0.001)。VLF预测硬脑膜撕裂伤的合并OR估计值为7.75,95%CI[2.41,24.87];P<0.001)。
    结论:VLF在管理TLF方面可能具有一些重要的诊断和治疗意义。VLF可能有助于区分AO型A3和A4骨折。VLF可能有助于术前预测硬膜裂伤的发生,从而选择最优的手术策略。临床和生物力学数据表明,VLF可能是指导爆裂骨折决策的有价值的修改器;然而,需要更多的研究来证实其对治疗结局的预后重要性.
    OBJECTIVE: Although vertical laminar fracture (VLF) is generally considered a severity marker for thoracolumbar fractures (TLFs), its exact role in decision-making has never been established. This scoping review aims to synthesize the research on VLF\'s role in the decision-making of TLFs.
    METHODS: A systematic review was conducted following PRISMA guidelines. We searched PubMed, Scopus, and Web of Science from inception to  June 11, 2023, for studies examining the association of VLF in thoracolumbar fractures with dural lacerations, neurological deficits, radiographic parameters, or treatment outcomes. Additionally, experimental studies that analyze the biomechanics of burst fractures with VLF were included. The studies extracted key findings, objectives, and patient population. A meta-analysis was performed for the association of VLF with dural laceration and neurological deficit, and ORs were pooled with a 95% confidence interval (CI).
    RESULTS: Twenty-eight studies were included in this systematic review, encompassing 2021 patients, and twelve were included in the meta-analysis. According to the main subject of the study, the association of VLF with a dural laceration (n = 14), neurological deficit (n = 4), radiographic parameters (n = 3), thoracolumbar fracture classification (n = 2), and treatment outcome (n = 2). Seven studies with a total of 1010 patients reported a significant association between VLF and neurological deficit (OR = 7.35, 95% CI [3.97, 14.25]; P < 0.001). The pooled OR estimates for VLF predicting dural lacerations were 7.75, 95% CI [2.41, 24.87]; P < 0.001).
    CONCLUSIONS: VLF may have several important diagnostic and therapeutic implications in managing TLFs. VLF may help to distinguish AO type A3 from A4 fractures. VLF may help to predict preoperatively the occurrence of dural laceration, thereby choosing the optimal surgical strategy. Clinical and biomechanical data suggest VLF may be a valuable modifier to guide the decision-making in burst fractures; however, more studies are needed to confirm its prognostic importance regarding treatment outcomes.
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