■这项研究旨在使用热格栅错觉(TGI)，疼痛处理和中枢机制的实验模型，评估慢性下腰痛（CLBP）患者对TGI相关感觉或疼痛的感知。
■对TGI（温暖/热量，冷,不愉快,疼痛,燃烧,刺痛,和刺痛）在66例CLBP患者中进行了检查，并与22例健康参与者进行了比较。CLBP的视觉模拟量表(VAS)评分，Oswestry残疾指数（ODI），并从纳入的CLBP患者中获得12项简短表格调查（SF-12）评分。
■CLBP组表现出对温暖/热的感觉的TGI感觉不那么强烈，不愉快,和疼痛比对照组。CLBP组感觉灼烧感低于对照组（2.77vs4.55，P=0.016）。在CLBP组中，ODI与不愉快程度（r=0.381，P=0.002）和刺痛感（r=0.263，P=0.033）之间存在显着相关性。SF-12的心理成分得分与热/热程度之间也存在显着相关性（r=-0.246，P=0.046）。不愉快(r=-0.292，P=0.017)，疼痛（r=-0.292，P=0.017），烧灼感(r=-0.280,P=0.023)。
■我们的结果可能有助于临床医生评估药物或干预措施管理集中式LBP的有效性。
UNASSIGNED: This study aimed to use thermal grill illusion (TGI), an experimental model of pain processing and central mechanisms, to evaluate the perception of TGI-related sensations or pain in patients with chronic lower back pain (CLBP).
UNASSIGNED: The perception of TGI (warmth/heat, cold, unpleasantness, pain, burning, stinging, and prickling) was examined in 66 patients with CLBP and compared with that in 22 healthy participants. The visual analog scale (VAS) scores for CLBP, Oswestry Disability Index (ODI), and 12-Item Short Form Survey (SF-12) scores were obtained from the included patients with CLBP.
UNASSIGNED: The CLBP group showed a less intense perception of TGI for sensations of warmth/heat, unpleasantness, and pain than the control group. The CLBP group felt burning sensations lesser than the control (2.77 vs 4.55, P=0.016). In the CLBP group, there were significant correlations between the ODI and the degree of unpleasantness (r=0.381, P=0.002) and prickling sensation (r=0.263, P=0.033). There were also significant correlations between the mental component score of the SF-12 and the degree of warmth/heat (r=-0.246, P=0.046), unpleasantness (r=-0.292, P=0.017), pain (r=-0.292, P=0.017), and burning sensations (r=-0.280, P=0.023).
UNASSIGNED: Our results may be useful for clinicians to evaluate the effectiveness of drugs or interventions to manage centralized LBP.
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