UNASSIGNED:骨肉瘤(OS)是儿童和青少年中最常见的原发性恶性骨肿瘤之一。OS发生率随年龄的变化而显著变化,峰值发生率在青少年年龄组。毛细血管扩张骨肉瘤(TOS)是OS的不寻常变体,形成所有操作系统的3-10%。文献中仅描述了这种罕见的OS变体的少数病例报告。
未经评估:我们报告了一名6岁女孩,在轻微创伤后出现左肱骨近端骨折。左肩X线示左肱骨近端溶骨性病变伴肱骨近端骨折。左侧肱骨近端溶骨性病变的开放活检提示高度异型细胞簇,如类骨物质和出血和坏死的局灶性区域提示TOS。该孩子开始接受化疗,然后进行保肢手术,并广泛切除左肱骨近端肿瘤。她完成了辅助化疗,目前在过去4年中表现良好。
UNASSIGNED:OS更常见于青少年膝关节周围的干干meta部。最常见的组织学类型是成骨细胞/成纤维细胞或软骨母细胞型。在<5岁年龄组中报告的病例很少,在5-10岁儿童中相对罕见。罕见的组织学变异,尤其是毛细血管扩张变体,在年幼的儿童中更常见,并且在上肢中更多。影像学检查主要显示溶骨性病变,与传统操作系统不同。该病例强调了组织病理学在骨肿瘤诊断中的最大作用,这将指导适当的治疗。
UNASSIGNED: Osteosarcoma (OS) is one of the most common primary malignant bone tumors in children and adolescents. OS incidence varies significantly with age and peak incidence is in adolescent age group. Telangiectatic osteosarcoma (TOS) is an unusual variant of OS, forming 3-10% of all OSs. Only few case reports of this rare variant of OS are described in the literature.
UNASSIGNED: We report a 6-year-girl who presented with fracture of the left proximal humerus after a trivial trauma. X-ray left shoulder showed osteolytic lesions in the left proximal humerus with fracture of proximal humerus. Open biopsy from the left proximal humerus osteolytic lesion suggested clusters of highly atypical cells like osteoid material and focal areas of hemorrhage and necrosis suggestive of TOS. The child was started on chemotherapy followed by limb-salvage surgery with wide resection of the tumor in the left proximal humerus. She completed her adjuvant chemotherapy and is currently doing well for the past 4 years.
UNASSIGNED: OS occurs more frequently in adolescents around the knee in the metaphyses. The most common histologic type is osteoblastic/fibroblastic or chondroblastic type. Very few cases have been reported in <5 years age group and it\'s relatively rare in 5-10-year-old children. Rare histologic variants, especially telangiectatic variant, are more common in younger children and occur more in upper limbs. Imaging reveals mainly osteolytic lesions, unlike in conventional OS. This case highlights the utmost role of histopathology in the diagnosis of the bone tumors which would guide the management appropriately.