Taxus,也被称为“植物中的黄金”,因为著名的药物以紫杉醇和多西他赛为重点,是紫杉科的一个属,几乎分布在世界各地。这些植物在中国传统医学中占有重要地位,其产品用于治疗排尿困难,肿胀和疼痛,糖尿病,女性月经不调。为了进一步研究和更好地应用红豆杉属植物,引用的1958年至2022年的参考文献是从WebofScience收集的,中国国家知识互联网(CNKI),SciFinder,和谷歌学者,和化学结构,分布,并总结了红豆杉样品中黄酮类化合物的生物活性。到目前为止,从红豆杉属植物中鉴定出59种不同骨架的黄酮,呈现出特殊的复合分布特征。据报道,这些化合物显示出显著的抗菌作用,抗衰老,抗阿尔茨海默氏症,抗糖尿病药,抗癌,抗抑郁药,抗利什曼病,抗炎,抗伤害和抗过敏,防病毒,抗脂肪酶,神经元保护,和肝脏保护活动,以及促进黑色素生成。黄酮类化合物代表了紫杉物种利用的一个很好的例子。在未来,黄酮类化合物的进一步药理和临床实验可以促进相关药物的制备。
Taxus, also known as \"gold in plants\" because of the famous agents with emphases on Taxol and Docetaxel, is a genus of the family Taxaceae, distributed almost around the world. The plants hold an important place in traditional medicine in China, and its products are used for treating treat dysuria, swelling and pain, diabetes, and irregular menstruation in women. In order to make a further study and better application of
Taxus plants for the future, cited references from between 1958 and 2022 were collected from the Web of Science, the China National Knowledge Internet (CNKI), SciFinder, and Google Scholar, and the chemical structures, distribution, and bioactivity of flavonoids identified from
Taxus samples were summed up in the research. So far, 59 flavonoids in total with different skeletons were identified from
Taxus plants, presenting special characteristics of compound distribution. These compounds have been reported to display significant antibacterial, antiaging, anti-Alzheimer\'s, antidiabetes, anticancer, antidepressant, antileishmaniasis, anti-inflammatory, antinociceptive and antiallergic, antivirus, antilipase, neuronal protective, and hepatic-protective activities, as well as promotion of melanogenesis. Flavonoids represent a good example of the utilization of the
Taxus species. In the future, further pharmacological and clinical experiments for flavonoids could be accomplished to promote the preparation of relative drugs.