UNASSIGNED：研究全身免疫指数（SII）和全身炎症反应指数（SIRI）对鼻咽癌患者预后的预测价值。
未经评估：两名研究人员独立搜索了PubMed，科克伦,Embase,和WebofScience数据库（直到2022年3月18日），用于所有关于SII的研究，SIRI,鼻咽癌患者的预后。纳入研究的质量评估采用纽卡斯尔-渥太华量表（NOS）进行评估。此外,使用双变量混合效应模型来探索预测价值.
UNASSIGNED：共包括9项符合要求的研究，涉及,3187例鼻咽癌患者。荟萃分析结果显示SII可能是OS的独立预测因子(HR=1.78,95CI[1.44-2.20],Z=5.28,P<0.05),SII也可能是PFS的独立预测因子(HR=1.66，95CI[1.36-2.03]，Z=4.94,P<0.05)。此外,SIRI也可以作为OS的独立预测因子(HR=2.88，95CI[1.97-4.19]，Z=5.51,P<0.05)。ROC面积为0.63,灵敏度为0.68(95CI[0.55-0.78]),特异性为0.55（95CI[0.47-0.62]），所有这些都表明SII对OS有一定的预测价值。
UNASSIGNED：SII和SIRI可作为预测鼻咽癌患者预后和生存状态的独立预测因子，具有一定的预测准确性。因此,在更新生存风险评估系统的研究中应考虑SII和SIRI。
UNASSIGNED：https://www。ytyhdyy.com/,标识符PROSPERO(CRD42022319678)。
UNASSIGNED: To study the predictive value of systemic immune index (SII) and systemic inflammatory response index (SIRI) in the prognosis of patients with nasopharyngeal carcinoma.
UNASSIGNED: Two researchers independently searched PubMed, Cochrane, Embase, and Web of Science databases (until March 18, 2022) for all studies on SII, SIRI, and prognosis in patients with nasopharyngeal carcinoma. Quality assessment of included studies was assessed using the Newcastle-Ottawa Scale (NOS). In addition, a bivariate mixed-effects model was used to explore predictive value.
UNASSIGNED: A total of 9 studies that satisfied the requirements were included, involving, 3187 patients with nasopharyngeal carcinoma. The results of the meta-analysis showed that SII could be an independent predictor of OS (HR=1.78, 95%CI [1.44-2.20], Z=5.28, P<0.05), and SII could also be an independent predictor of PFS (HR=1.66, 95%CI [1.36-2.03], Z=4.94, P<0.05). In addition, SIRI could also serve as an independent predictor of OS (HR=2.88, 95%CI [1.97-4.19], Z=5.51, P<0.05). The ROC area was 0.63, the sensitivity was 0.68 (95%CI [0.55-0.78]), and the specificity was 0.55 (95%CI [0.47-0.62]), all of which indicated that SII had a certain predictive value for OS.
UNASSIGNED: SII and SIRI can be used as independent predictors to predict the prognosis and survival status of patients with nasopharyngeal carcinoma and have certain predictive accuracy. Therefore, SII and SIRI should be considered in studies that update survival risk assessment systems.
UNASSIGNED: https://www.ytyhdyy.com/, identifier PROSPERO (CRD42022319678).
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