目的:评估对人类牙科植入物的组织形态学骨与植入物接触(BIC)有影响的因素。
方法:使用纳入/排除标准,我们在5个数据库中检索了符合条件的研究,并在11种期刊中进行了手工检索.共分配351篇文章进行全文分析。提取的数据被分配到比较统计评估和荟萃分析。
结果:共55篇文献纳入分析。在下颌骨植入物的比较评估和荟萃分析中发现的平均BIC(分别为70.97和69.744±3.304)高于上颌骨(分别为53.24和56.692±3.598;P=.000和P=.008)。前下颌骨(79.42)和上颌骨(74.19)的平均BIC高于后下颌骨(69.14)和上颌骨(36.68)(P<0.05)。在市售植入物和实验微植入物的BIC中检测到差异(P<0.05)。比较评估和荟萃分析显示,常规加载植入物(分别为75.70和75.786±4.889)的BIC高于未加载植入物(分别为54.07和53.24±4.971)和立即加载植入物(分别为58.53和68.831±4.972;P=.000和P=.004)。
结论:根据文献的荟萃分析,可以得出以下结论:下颌骨的BIC高于上颌骨。前部的BIC高于后部。与解剖区域结合的植入物设计影响BIC的量。在后部区域中放置具有不同表面的实验性微植入物总是导致低且几乎相当的BIC。负荷状态和愈合期似乎对BIC有影响。需要具体的报告指南来改进人类BIC研究的报告。
OBJECTIVE: To evaluate factors that have an influence on histomorphometric bone-to-implant contact (BIC) of dental implants in humans.
METHODS: Using inclusion/exclusion criteria, eligible studies were searched in five databases and handsearched in 11 journals. A total of 351 articles were assigned to full text analysis. The extracted data were assigned to comparative statistical assessments and meta-analysis.
RESULTS: A total of 55 articles were included in the analysis. The mean BIC found in comparative assessments and meta-analysis of implants in the mandible (70.97 and 69.744 ± 3.304, respectively) was higher than those in the maxilla (53.24 and 56.692 ± 3.598; P = .000 and P = .008, respectively). The mean BIC in the anterior mandible (79.42) and maxilla (74.19) were higher than the posterior mandible (69.14) and maxilla (36.68) (P < .05). Differences were detected in BIC of commercially available implants and experimental micro-implants (P < .05). Comparative assessments and meta-analysis showed that conventionally loaded implants (75.70 and 75.786 ± 4.889, respectively) had higher BIC than unloaded (54.07 and 53.24 ± 4.971, respectively) and immediately loaded implants (58.53 and 68.831 ± 4.972; P = .000 and P = .004, respectively).
CONCLUSIONS: Based upon a meta-analysis of the literature the following conclusions can be made: The BIC in the mandible is higher than the maxilla. The BIC is higher in the anterior than the posterior regions. The implant design coupled with the anatomical region affects the amount of BIC. Placement of experimental micro-implants with different surfaces in the posterior region always result in low and almost comparable BIC. The loading state and healing period seems to have an influence on BIC. Specific reporting
guidelines are required to improve reporting of studies on human BIC.