Subarachnoid Hemorrhage, Traumatic

蛛网膜下腔出血,创伤性
  • 文章类型: Systematic Review
    外伤性蛛网膜下腔出血(tSAH)常与创伤性脑损伤(TBI)合并,并可能通过血管痉挛和随后的迟发性脑缺血(DCI)等血管变化引起继发性损伤。虽然动脉瘤性SAH在血管痉挛和DCI方面得到了充分的研究,但关于tSAH和血管痉挛和DCI的患病率以及在这种情况下血管痉挛的后果知之甚少。当需要治疗时,以及应该实施哪些管理策略。在这里,对TBI患者症状性血管痉挛的病例进行了系统的文献回顾,据报道与tSAH有关联,总结了血管痉挛和DCI的危险因素,并讨论了诊断和管理中的共性。在20项研究中,确定了38例患者的临床特征和治疗结果,其中TBI合并血管痉挛的患者接受了医学或血管内治疗。在每个类别都有可用数据的案例中,平均年龄为48.7±20.3岁(n=31),GCS在演示文稿10.6±4.5(n=35),100%患有tSAH(n=29)。在损伤后第8.4±3.0天(n=30)平均诊断为指示DCI的症状性血管痉挛。56.6%的病例(n=30)出现了与血管痉挛相关的新的缺血性变化,证实了DCI。讨论了治疗策略,12例接受血管内治疗的患者中有11例,26例接受药物治疗的患者中有19例存活出院。总之,在中度和重度TBI中,tSAH与血管痉挛和DCI相关,具有症状性血管痉挛和随后发生DCI的临床和影像学证据的患者可能会受益于血管内或医疗管理策略。
    Traumatic subarachnoid hemorrhage (tSAH) is frequently comorbid with traumatic brain injury (TBI) and may induce secondary injury through vascular changes such as vasospasm and subsequent delayed cerebral ischemia (DCI). While aneurysmal SAH is well studied regarding vasospasm and DCI, less is known regarding tSAH and the prevalence of vasospasm and DCI, the consequences of vasospasm in this setting, when treatment is indicated, and which management strategies should be implemented. In this article, a systematic review of the literature that was conducted for cases of symptomatic vasospasm in patients with TBI is reported, association with tSAH is reported, risk factors for vasospasm and DCI are summarized, and commonalities in diagnosis and management are discussed. Clinical characteristics and treatment outcomes of 38 cases across 20 studies were identified in which patients with TBI with vasospasm underwent medical or endovascular management. Of the patients with data available for each category, the average age was 48.7 ± 20.3 years (n = 31), the Glasgow Coma Scale score at presentation was 10.6 ± 4.5 (n = 35), and 100% had tSAH (n = 29). Symptomatic vasospasm indicative of DCI was diagnosed on average at postinjury day 8.4 ± 3.0 days (n = 30). Of the patients, 56.6% (n = 30) had a new ischemic change associated with vasospasm confirming DCI. Treatment strategies are discussed, with 11 of 12 endovascularly treated and 19 of 26 medically treated patients surviving to discharge. tSAH is associated with vasospasm and DCI in moderate and severe TBI, and patients with clinical and radiographic evidence of symptomatic vasospasm and subsequent DCI may benefit from endovascular or medical management strategies.
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  • 文章类型: Meta-Analysis
    本系统综述的目的是基于现有的关于初始CT成像预测儿科患者严重创伤性脑损伤(TBI)死亡率的能力的研究,分析证据。一位经验丰富的图书馆员根据纳入和排除标准搜索了所有现有研究。这些研究由两名失明的评论者进行筛选。在搜索中包含的3277项研究中,影像学检查结果的患病率和死亡率的数据只能从22项研究中提取.其中一些研究具有患者特定的数据,将特定的影像学发现与结果相关,允许数据分析,曲线下面积(AUC)和受试者工作特性(ROC)的计算,并为每个发现生成一个森林地块。提取数据以计算灵敏度(SN),特异性(SP),阳性预测值(PPV),负预测值(NPV),AUC,和ROC用于硬膜外血肿(EDH),硬膜下血肿(SDH),外伤性蛛网膜下腔出血(tSAH),颅骨骨折,和水肿。共有2219名患者,747名女性和1461名男性。在总数中,564例患者死亡,1651例存活;293例患者患有SDH,76有EDH,347有tSAH,244例颅骨骨折,416有水肿。纳入的研究具有较高的偏倚性和较低的证据等级。在不同的CT扫描结果中,脑水肿的SN最高,PPV,NPV,AUC。EDH具有最高的SP来预测住院死亡率。
    The purpose of this systematic review was to analyze evidence based on existing studies on the ability of initial CT imaging to predict mortality in severe traumatic brain injuries (TBIs) in pediatric patients. An experienced librarian searched for all existing studies based on the inclusion and exclusion criteria. The studies were screened by two blinded reviewers. Of the 3277 studies included in the search, data on prevalence of imaging findings and mortality rate could only be extracted from 22 studies. A few of those studies had patient-specific data relating specific imaging findings to outcome, allowing the data analysis, calculation of the area under the curve (AUC) and receiver operating characteristic (ROC), and generation of a forest plot for each finding. The data were extracted to calculate the sensitivity (SN), specificity (SP), positive predictive value (PPV), negative predicted value (NPV), AUC, and ROC for extradural hematoma (EDH), subdural hematoma (SDH), traumatic subarachnoid hemorrhage (tSAH), skull fractures, and edema. There were a total of 2219 patients, 747 females and 1461 males. Of the total, 564 patients died and 1651 survived; 293 patients had SDH, 76 had EDH, 347 had tSAH, 244 had skull fractures, and 416 had edema. The studies included had high bias and lower grade of evidence. Out of the different CT scan findings, brain edema had the highest SN, PPV, NPV, and AUC. EDH had the highest SP to predict in-hospital mortality.
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  • 文章类型: Journal Article
    每年有6900万人患有创伤性脑损伤(TBI),TBI是蛛网膜下腔出血(SAH)的最常见原因。创伤性SAH(TSAH)已被描述为导致进行性神经系统恶化以及发病率和死亡率增加的不良预后因素。数量有限的研究,然而,评估创伤背景下SAH诊断和治疗的最新趋势。本范围审查的目的是了解有关TSAH诊断标准和管理的证据的范围和类型。这项范围审查是按照乔安娜·布里格斯研究所的范围审查方法进行的。审查包括成人SAH继发于创伤,其中孤立的TSAH(iTSAH)是指在没有任何其他创伤性影像学颅内病理的情况下存在SAH,和TSAH是指SAH的存在,可能或存在额外的创伤性影像学颅内病理。从每项研究中提取的数据包括研究目标,国家,方法论,人口特征,结果衡量标准,调查结果摘要,未来的指令。30项研究符合纳入标准。研究按主题分为五类:TSAH与轻度TBI(mTBI)相关,n=13),和严重TBI(n=3);临床管理和诊断(n=9);影像学检查(n=3);和动脉瘤性TSAH(n=1)。在30项研究中,两个来自低收入和中等收入国家(LMIC),不包括中国,几乎是一个高收入国家。与mTBI相关的TSAH患者临床恶化和手术干预的风险非常低,在考虑入住重症监护病房时应保守治疗。赫尔辛基和斯德哥尔摩计算机断层扫描评分系统,除了美国伤害量表,肌酐水平,年龄决策树,在预测结果和死亡时可能是有价值的工具。
    Sixty-nine million people have a traumatic brain injury (TBI) each year, and TBI is the most common cause of subarachnoid hemorrhage (SAH). Traumatic SAH (TSAH) has been described as an adverse prognostic factor leading to progressive neurological deterioration and increased morbidity and mortality. A limited number of studies, however, evaluate recent trends in the diagnosis and management of SAH in the context of trauma. The objective of this scoping review was to understand the extent and type of evidence concerning the diagnostic criteria and management of TSAH. This scoping review was conducted following the Joanna Briggs Institute methodology for scoping reviews. The review included adults with SAH secondary to trauma, where isolated TSAH (iTSAH) refers to the presence of SAH in the absence of any other traumatic radiographic intracranial pathology, and TSAH refers to the presence of SAH with the possibility or presence of additional traumatic radiographic intracranial pathology. Data extracted from each study included study aim, country, methodology, population characteristics, outcome measures, a summary of findings, and future directives. Thirty studies met inclusion criteria. Studies were grouped into five categories by topic: TSAH associated with mild TBI (mTBI), n = 13), and severe TBI (n = 3); clinical management and diagnosis (n = 9); imaging (n = 3); and aneurysmal TSAH (n = 1). Of the 30 studies, two came from a low- and middle-income country (LMIC), excluding China, nearly a high-income country. Patients with TSAH associated with mTBI have a very low risk of clinical deterioration and surgical intervention and should be treated conservatively when considering intensive care unit admission. The Helsinki and Stockholm computed tomography scoring systems, in addition to the American Injury Scale, creatinine level, age decision tree, may be valuable tools to use when predicting outcome and death.
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  • 文章类型: Case Reports
    Traumatic subarachnoid hemorrhage (SAH) is a common finding following traumatic brain injury. In some cases, it can be associated with hydrocephalus. This type of hemorrhage is mostly caused by the rupture of small vessels in the brain and is usually managed conservatively.
    We present a case of a 60-year-old woman who presented with traumatic luxation of the eye following a fall. This resulted in diffuse SAH (Fisher grade IV) with associated hydrocephalus. We also report on 3 previous similar cases found in the literature. Avulsion of the ophthalmic artery was found to be the cause of the traumatic SAH. Apart from cerebrospinal fluid diversion using an external ventricular drain, the case was managed conservatively. There was no evidence of delayed clinical or radiologic vasospasm.
    Traumatic avulsion of the ophthalmic artery may result in diffuse SAH, mimicking that of aneurysmal rupture. This case shows that management of early complications, such as hydrocephalus and seizures, should be the main aim. Surgical or endovascular treatment of the injured artery, however, would be unnecessary.
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  • 文章类型: Case Reports
    背景:颅内假性动脉瘤是一种罕见的实体,文献中描述的案例很少,主要与创伤性脑损伤史有关。创伤性动脉瘤占所有颅内动脉瘤的<1%。特别是,脑膜中动脉(MMA)动脉瘤并不常见,通常由颞部颅骨骨折引起。文献报道了约40例创伤性MMA动脉瘤,只有28个非创伤性动脉瘤被报道,通常与高流量条件有关。这些动脉瘤的行为在很大程度上是未知的:自发消退和动脉瘤生长,导致随后的破裂,已被报道。手术和血管内治疗对MMA动脉瘤是可行的;然而,标准治疗没有定义。
    方法:我们报告了一例右MMA的创伤性假性动脉瘤,并提供了文献综述。
    结论:MMA动脉瘤是一种罕见的实体,在创伤性脑损伤或诱发因素的情况下必须考虑。诊断和积极治疗是强制性的,防止它们破裂的毁灭性后果。血管内和外科技术是明确的和可用的,即使他们中的任何一个都没有表现出优越性。
    BACKGROUND: Intracranial pseudoaneurysm is a rare entity, with few cases described in the literature, and is mostly associated with a history of traumatic brain injury. Traumatic aneurysms comprise <1% of all intracranial aneurysms. In particular, middle meningeal artery (MMA) aneurysms are uncommon and usually caused by a skull fracture in the temporal region. About 40 traumatic MMA aneurysms are reported in the literature, and only 28 nontraumatic aneurysms are reported, usually related to high-flow conditions. The behavior of these aneurysms is largely unknown: both spontaneous resolution and aneurysm growth, leading to subsequent rupture, have been reported. Surgical and endovascular management are feasible for MMA aneurysms; however, the criterion standard treatment is not defined.
    METHODS: We report the case of a traumatic pseudoaneurysm of the right MMA treated with an endovascular approach and provide a review of the literature.
    CONCLUSIONS: Aneurysms of the MMA are a rare entity that must be taken into account in the setting of a traumatic brain injury or predisposing factors. The diagnosis and aggressive treatment are mandatory, preventing the devastating consequences of their rupture. Endovascular and surgical techniques are well defined and available, even though there is not a demonstrated superiority in any of them.
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  • 文章类型: Case Reports
    Fatal subarachnoid hemorrhage (SAH) caused by anterior communicating artery (ACoA) rupture is a rare event in medicolegal practice. Anatomical variations of the ACoA tend to make its anatomical structure, and as a result, blood flow through it, more complicated, which may increase hemodynamic stress and cause weak spots in the affected blood vessels. Variant ACoAs are prone to rupture in the event of a blunt-force trauma. Here, we report a fatal case of SAH caused by the rupture of a variant ACoA when the victim\'s head was struck from behind, causing the head to rotate and the victim to fall forward onto the ground. A medicolegal autopsy revealed diffuse basal SAH and ACoA duplication. The smaller of the two variant ACoA branches had ruptured near its junction with the right anterior cerebral artery. No basal aneurysms or other fatal diseases or injuries were found. This case highlights the significance of anatomical variation in forensic pathology.
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  • 文章类型: Case Reports
    在人际暴力行为中,由于使用螺丝刀作为伤人剂而造成的头部穿透性伤害很少发生。本文旨在更新和总结有关穿透性颅脑螺丝刀刺伤的相关文献,并报告新的螺丝刀攻击案例。回顾了许多研究以调查发病率,分布,共同发现,损伤机制,鉴别诊断标准,并发症,治疗,颅脑螺丝刀刺伤的预后。观察到创伤严重程度取决于螺丝刀的横截面积和损伤的解剖区域。颅脑螺丝刀伤主要是人际暴力,死亡率约为47.6%。在23.8%的事件中,由于小的伤口,创伤在入院时被忽视,因此,最初没有意识到伤害的严重程度。
    Penetrating head injuries due to the use of screwdrivers as wounding agents in acts of interpersonal violence seldom occur. The aim of this article is to update and summarize the relevant literature on penetrating craniocerebral screwdriver stab wounds and to report a new case of screwdriver assault. A number of studies were reviewed to investigate the incidence, distribution, common findings, mechanism of injury, differential diagnostic criteria, complications, treatment, and prognosis of craniocerebral screwdriver stab injuries. It was observed that the degree of traumatic severity depends on the cross-sectional area of the screwdriver and the anatomical region of injury. Craniocerebral screwdriver injuries are mainly cases of interpersonal violence and the mortality rate is approximately 47.6%. In 23.8% of the incidents, the trauma is overlooked on admission because of the small entry wound and, thus, the severity of the injury is not initially appreciated.
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  • 文章类型: Case Reports
    Penetrating injury to the head, with the exception of missile injuries is rare owing to thick calvarium. Orbital and temporal areas are comparatively vulnerable to penetrating injuries, due to their relative thinness. A case is presented in which a man killed his wife by forcefully thrusting a screw driver into her cranial cavity. The deceased presented to the hospital with the screw driver embedded in her head. She was declared as \'brought dead on arrival\' at the emergency of the hospital. Pre-autopsy plain radiography and Computed Tomography (CT) of the head were done to assess the extent of brain damage. The peculiarity of this case lies in the fact that screw driver as a stabbing weapon in the head is very rarely used. In such cases, there is a need to perform radiography and CT with the weapon in-situ for better interpretation on injuries. In this paper role of radiography and CT in intra cranial penetration is discussed with review of literature.
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  • 文章类型: Case Reports
    With an incidence of less than 1-3 per million, pediatric aneurysms are rare clinical entities. A traumatic etiology is implicated in a large proportion of these cases, leading to the formation of both \'false\' and \'true\' aneurysms. These occur most often in the distal circulation, but have also been described in the supraclinoid distal internal carotid artery (ICA). Blood blister aneurysms are also found in this location; however, they have not been described in the pediatric population. We report the case of a 15-year-old male who presented following cranial trauma with diffuse basal subarachnoid hemorrhage and limited additional intracranial pathology. Computed tomography angiography demonstrated a small, 2-mm blister-like aneurysm arising from the dorsal surface of the left supraclinoid ICA at a non-branching site. Despite early endovascular treatment with Guglielmi detachable coils, the lesion continued to grow over subsequent studies, necessitating open surgical clipping. At the time of surgery, gross pathology of the native ICA was observed, raising the possibility of a preexisting blood-blister aneurysm. We review the epidemiology, pathophysiology and diagnostic considerations of these lesions. The endovascular and surgical management of these complex non-branching supraclinoid ICA aneurysms is also discussed.
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  • 文章类型: Case Reports
    Odontoid fractures have been classified by Anderson and D\'Alonzo into three main categories. The most unstable injuries, type II fractures involve the base of the odontoid peg at the junction with the C2 body. Due to the proximity of vital neural structures, fracture of the odontoid process may result in instability and fatal neurological damage. Treatment aims to re-establish stability of the atlanto-axial complex by restoring the odontoid process. This may be achieved by conservative or surgical treatment. Anterior screw fixation of the odontoid peg is an interresting alternative surgical option but this technique has a significant complication rate. However, vascular injury is very rare with three case reported in the literature: one case of an intracranial vertebral artery (VA) injury, one case of a cervical internal carotid artery (ICA) injury and one case of anterior pseudoaneurysm of the spinal artery branch. We report a new case of long term vascular injury after screw fixation revealed by a subarachnoid hemorrhage. We discuss the incidence, the mechanisms of injury and the conditions necessary for the occurrence of this complication.
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