背景:全球三分之二的成年人在其生命中的某个阶段会经历下腰痛。在以下案例系列中,我们介绍了四名患者的骶髂(SI)关节不稳定和严重的慢性下腰痛,其他治疗方式难以治疗。
目的:我们研究了富血小板血浆(PRP)注射液的疗效,一种新颖的生物矫正疗法,减少SI关节疼痛,提高生活质量,并保持临床效果。
方法:简式麦吉尔疼痛问卷(SFM),数字评级量表(NRS),和Oswestry下腰痛和残疾指数用于评估治疗前,治疗后12个月和48个月。
结果:治疗后12个月随访时,来自所有患者的汇总数据报告关节稳定性明显改善,疼痛有统计学意义的减轻,以及生活质量的提高。PRP的临床益处在治疗后4年仍然显著。
结论:富含血小板的血浆治疗在慢性SI关节痛患者的疼痛减轻和功能改善方面具有临床应用价值。治疗后1年和4年,关节稳定性和腰背痛的改善得以维持。
BACKGROUND: Two-thirds of adults worldwide will experience low back pain at some point in their life. In the following
case series, we present four patients with sacroiliac (SI) joint instability and severe chronic low back pain, which was refractory to other treatment modalities.
OBJECTIVE: We investigated the efficacy of platelet-rich plasma (PRP) injections, a novel orthobiologic therapy, for reducing SI joint pain, improving quality of life, and maintaining a clinical effect.
METHODS: Short-form McGill Pain Questionnaire (SFM), Numeric Rating Scale (NRS), and Oswestry Low Back Pain and Disability Index were used for evaluation of treatment at pretreatment, 12-months and 48-months after treatment.
RESULTS: At follow-up 12-months post-treatment, pooled data from all patients reported a marked improvement in joint stability, a statistically significant reduction in pain, and improvement in quality of life. The clinical benefits of PRP were still significant at 4-years post-treatment.
CONCLUSIONS: Platelet-rich plasma therapy exhibits clinical usefulness in both pain reduction and for functional improvement in patients with chronic SI joint pain. The improvement in joint stability and low back pain was maintained at 1- and 4-years post-treatment.