背景:亚硝酸钠是一种有效的氧化剂,可通过高铁血红蛋白的形成损害氧气的运输和输送。已知临床表现可诱发高铁血红蛋白血症,心律失常,低血压,甚至死亡。虽然以前曾发生过亚硝酸钠被污染的水和食物意外中毒,近年来,自杀中毒人数激增。
方法:我们提供了2名在互联网市场订购“自杀粉”后通过亚硝酸钠自杀的患者的病例报告。他们试图通过摄入亚硝酸钠自杀后被带到急诊室。他们经历了呼吸困难,紫癜,和轻微的恶心。
方法:根据他们的病史和血液检查,最初诊断为高铁血红蛋白血症。
结果:患者在急诊科接受亚甲蓝解毒治疗。患者经过神经精神评估和精神疾病治疗后出院,自杀意念,和自杀企图。他们告诉我们,他们购买亚硝酸钠用于自杀目的是多么简单和容易。
结论:关于亚硝酸钠用于自杀和缺乏适当监管的广泛共享信息,急性中毒的发生率会增加。这增加了内科医生遇到原因不明的紫癜和高铁血红蛋白血症的机会。在原因不明的紫癜或高铁血红蛋白血症的情况下,临床怀疑亚硝酸钠中毒是必要的。我们想强调购买亚硝酸钠用于自杀目的是多么简单和容易。
BACKGROUND: Sodium nitrite is a potent oxidizing agent that impairs oxygen transport and delivery through methemoglobin formation. Clinical manifestations are known to induce methemoglobinemia, dysrhythmia, hypotension, and even death. While accidental intoxication of sodium nitrite by contaminated water and food has previously occurred, there has been a substantial upsurge in suicide intoxication in recent years.
METHODS: We present
case reports of 2 patients who attempted suicide by sodium nitrite after ordering a \"suicide powder\" on the internet market. They were brought to the emergency department after attempting suicide by ingesting sodium nitrite. They experienced dyspnea, cyanosis, and mild nausea.
METHODS: Based on their history and blood tests, methemoglobinemia was initially diagnosed.
RESULTS: The patients received methylene blue antidotal therapy in the emergency department. The patients were discharged after neuropsychiatric evaluation and treatment for mental illness, suicidal ideation, and suicide attempts. They informed us of how simple and easy it was for them to buy sodium nitrite for suicidal purposes.
CONCLUSIONS: With widely shared information on the usage of sodium nitrite for suicide and the absence of proper regulation, the incidence of acute poisoning will increase. This increases physicians\' chances of encountering unexplained cyanosis and methemoglobinemia. Clinical suspicion of sodium nitrite intoxication is warranted in cases of unexplained cyanosis or methemoglobinemia. We want to highlight how simple and easy it is to buy sodium nitrite for suicidal purposes.