Skin Transplantation

皮肤移植
  • 文章类型: Journal Article
    传统的皮瓣修复手术有几个缺点,包括操作复杂性,供体部位受损,和高风险。在这个系列中,作者探索了使用可吸收明胶海绵(AGSs)和自体大腿皮肤移植物修复外伤引起的外露肌腱伤口的替代方法.本报告介绍了伤口清创术后2例下肢皮肤坏死伴肌腱暴露。治疗方法包括早期清创,负压伤口治疗,并用0.9%氯化钠冲洗伤口。在获得控制的伤口感染后,将AGS应用于暴露的肌腱以防止变性并促进伤口愈合。随后,使用AGS和从大腿收获的0.25毫米厚的自体网状皮肤移植物修复肉芽组织无法覆盖肌腱的区域。在这两种情况下都实现了完全的伤口愈合,植皮后的第20天和第12天,分别。所提出的方法在修复暴露的肌腱伤口方面被证明是成功的,有效预防感染和坏死。
    UNASSIGNED: Conventional flap repair surgery has several drawbacks, including operational complexity, donor site damage, and high risk. In this case series, the authors explored an alternative approach for repairing exposed tendon wounds caused by trauma using absorbable gelatin sponges (AGSs) and autologous thigh skin grafts. This report presents two cases of lower-extremity skin necrosis with tendon exposure following wound debridement. The treatment approach involved early debridement, negative-pressure wound therapy, and wound irrigation with 0.9% sodium chloride. Upon achieving controlled wound infection, AGSs were applied to the exposed tendon to prevent degeneration and promote wound healing. Subsequently, areas where granulation tissue failed to cover the tendon were repaired using AGSs and 0.25-mm-thick autologous mesh skin grafts harvested from the thigh. Complete wound healing was achieved in both cases, on the 20th and 12th day after skin grafting, respectively. The proposed method proved successful in repairing exposed tendon wounds, effectively preventing infection and necrosis.
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  • 文章类型: Journal Article
    燃烧后脱发提出了复杂的医学挑战,涉及皮肤病和精神疾病。头发移植的使用已被证明是对这种情况的显着改善。然而,当前的管理涉及各种技术,每个都有优点和缺点。进行性皮肤扩张,手术疤痕减少,和含有毛囊的皮肤移植物产生不令人满意的美学效果,并且作为火灾受害者的一线治疗的适用性有限。到目前为止,在这种情况下,卵泡单位提取(FUE)已被证明是最通用的程序之一,有可能恢复与导致创伤性脱发的创伤前外观非常相似的自然解剖学轮廓。此外,它有助于改善相关的精神病合并症,促进适当的社会融合和提高整体生活质量。本报告重点介绍一例因三度烧伤导致严重精神合并症的烧伤后脱发和严重面部变形,在连续三次接受头皮和眉毛头发的FUE治疗后,这得益于适当的社会融合和生活质量的提高。
    Post-combustion alopecia presents a complex medical challenge with implications spanning dermatological and psychiatric disorders. The use of hair transplantation has proven to be a significant improvement for this condition. However, the current management involves various techniques, each with advantages and disadvantages. Progressive skin expansions, surgical scar reduction, and skin grafts containing hair follicles yield unsatisfactory aesthetic outcomes and have limited applicability as a first-line treatment for fire victims. So far, follicular unit extraction (FUE) has proven to be one of the most versatile procedures in such cases, having the potential to restore a natural anatomical profile closely resembling the pre-traumatic appearance that led to the traumatic alopecia. Additionally, it contributes to the improvement of associated psychiatric comorbidities, facilitating proper social reintegration and enhancing overall quality of life. This report focuses on a case of post-combustion alopecia and severe facial distortion due to third-degree burns resulting in severe psychiatric comorbidities, which benefited from a proper social reintegration and improvement of the quality of life after three consecutive sessions of FUE for scalp and eyebrow hair.
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  • 文章类型: Case Reports
    复杂和严重的下肢损伤的管理是骨科医生具有挑战性。当缺陷的主要或次要闭合不可行时,需要使用移植物(厚度分开或全厚度)或皮瓣(带蒂或游离)的复杂程序。这些手术由专业整形外科医生进行,有很高的不良反应风险,甚至在供体和受体部位的发病率都很高。此外,分裂厚度的皮肤移植物(STSGs)往往导致不满意的结果在机械稳定性方面,灵活性,和美学由于缺乏潜在的真皮组织。因此,真皮替代品,例如MatriDerm(MedSkinSolutions博士SuwelackAG,Billerbeck,德国),已被提出并进一步开发为解决与STSG结合的全层伤口缺陷的管理的治疗选择。我们的目的是介绍一例用MatriDerm联合自体STSG治疗的手指创伤性截肢后左脚创伤后全层伤口缺损的病例。此外,我们对文献进行了系统回顾,以描述MatriDerm联合STSGs在骨科病例中的应用效果.
    The management of complex and severe lower-extremity injuries is challenging for the orthopedic surgeon. When the primary or secondary closure of the defect is not feasible, complex procedures with graft (split-thickness or full-thickness) or flap (pedicled or free) are required. These procedures are performed by specialized plastic surgeons and are at high risk for adverse effects, even high morbidity among both the donor and acceptor sites. Furthermore, split-thickness skin grafts (STSGs) often lead to unsatisfactory results in terms of mechanical stability, flexibility, and aesthetics due to the lack of underlying dermal tissue. Consequently, dermal substitutes, such as MatriDerm (MedSkin Solutions Dr Suwelack AG, Billerbeck, Germany), have been proposed and further developed as a treatment option addressing the management of full-thickness wound defects in conjunction with STSGs. We aimed to present a case of post-traumatic full-thickness wound defect of the left foot after traumatic amputation of the digits that was treated with MatriDerm combined with autologous STSG. In addition, we performed a systematic review of the literature to delineate the efficacy of the use of MatriDerm combined with STSGs in orthopedic cases exclusively.
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  • 文章类型: Journal Article
    全层皮肤移植物是重建手术的重要工具。矩形或方形继发性缺损通常在进行交叉指皮瓣或同指岛状皮瓣后发生。采用传统的梭形椭圆设计,修剪多余的移植组织是必要的。双直角三角形全层皮肤移植物旨在纠正问题。
    Full-thickness skin grafts are essential tools for reconstructive surgery. Rectangular or square secondary defect usually occurs after performing a cross-finger flap or homodigital island flap. With the traditional fusiform ellipse design, trimming out excess graft tissue is necessary. Double right triangular shape full-thickness skin grafts are designed to correct the problem.
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  • 文章类型: Journal Article
    指床重建在指尖创伤后至关重要,影响功能和美学。在这篇文章中,作者描述了一例食指远端指骨部分截肢并甲床剩余部分裂伤的病例。一个创伤升高的皮肤脂肪皮瓣覆盖了指尖上暴露的骨头,保持手指的长度和灵敏度在径向侧。前臂的全层皮肤移植物闭合了指腹上的继发性缺损。甲床缝合可防止疤痕和指甲畸形,和临时人造塑料指甲替代品保持甲床的形状。临时人工指甲置换保护再生指尖床,促进愈合,防止指甲畸形。适当适应撕裂的甲床边缘,由患者自己的指甲或临时人造指甲支撑,对于最佳的指尖恢复至关重要,包括适当的指甲形状。
    Nail bed reconstruction is crucial after fingertip trauma, impacting both function and aesthetics. In this article, the authors describe a case of partial distal phalanx amputation of the index finger with laceration of the nail bed\'s remaining part. A traumatically elevated skin-fat flap covered the exposed bone on the fingertip, preserving finger length and sensitivity on the radial side. A full-thickness skin graft from the forearm closed a secondary defect on the finger pulp. Nail bed suturing prevented scarring and nail deformity, and a temporary artificial plastic nail replacement maintained the nail bed\'s shape. Temporary artificial nail replacements protect the regenerating fingertip bed, promote healing, and prevent nail deformities. Proper adaptation of lacerated nail bed edges, supported by either the patient\'s own nail or a temporary artificial nail, is crucial for optimal fingertip restoration, including proper nail shape.
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  • 文章类型: Review
    因为头部和颈部是烧伤最常见的部位之一,最重要的是,整形外科医生和整形外科护士了解治疗颈部挛缩的最有效的手术方法和每种病例所需的重建技术。我们介绍了一名42岁妇女的病例,该妇女表现出严重的烧伤后颈部挛缩,并用带蒂的枕颈背皮瓣重建。我们首先封闭了供体部位的伤口,并完全覆盖了缺损,效果良好。除了传统的皮肤移植,真皮基质,和显微外科技术,使用枕背皮瓣应考虑重建烧伤后颈部挛缩,因为它提供了良好的美学和功能结果,提供足够的组织和柔韧的皮肤,并导致最小的供体部位发病率。
    Because the head and neck are one of the most frequent locations of burns, it is of paramount importance that plastic surgeons and plastic surgical nurses understand the most effective surgical methods for treating neck contractures and the reconstructive technique required for each case. We introduce the case of a 42-year-old woman who presented with a severe postburn neck contracture that was reconstructed with a pedicled occipito-cervico-dorsal flap. We closed the donor-site wound primarily and completely covered the defect with good results. In addition to conventional skin grafts, dermal matrices, and microsurgical techniques, using an occipito-cervico-dorsal flap should be considered for reconstructing postburn neck contractures as it offers good aesthetic and functional outcomes, provides enough tissue and pliable skin, and results in minimal donor-site morbidity.
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  • 文章类型: Case Reports
    在感染性休克患者中,由于高剂量去甲肾上腺素(NE)引起的缺血性肢体坏死并不常见。不幸的是,坏死部位截肢是唯一可用的治疗方法。用自体皮肤移植物重建下肢截肢造成的缺损是具有挑战性的。在此,我们报告了一例感染性休克患者在服用高剂量NE>1μcg/kg/min后上肢和下肢手指坏死的病例。未检测到导致感染性休克的感染源。由于无法修复受损的脉管系统,并且患者的生命受到威胁,因此进行了手术截肢。患者大腿自体皮肤移植物覆盖较大缺损。所包括的数字显示了之前的四肢外观,截肢后,在皮肤移植期间和之后。
    Ischemic limb necrosis due to high dose of norepinephrine (NE) in a patient with septic shock is uncommon. Unfortunately, amputation of necrotic parts is the only available treatment. Reconstruction with skin autografts for defects resulting from the amputation of the lower limbs is challenging. Herein we report a case of digit necrosis in the upper and lower limbs after administration of a high dose of NE > 1 μcg/kg/min in a patient with septic shock. The source of infection that led to septic shock was not detected. Surgical amputation was performed as it was impossible to repair impaired vasculature and patients\' life was endangered. Large defects were covered with skin autografts from the patient\'s thighs. The included figures demonstrate the extremities\' appearance before, after amputation, during and after skin graft transplantation.
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  • 文章类型: Case Reports
    虽然筋膜切开术是筋膜室综合征的唯一紧急治疗选择,由此产生的开放性伤口为并发症留下了空间。伤口的闭合可以通过不同的技术来完成,包括厚薄的皮肤移植物,负压治疗,可吸收的倒刺缝合系统和电缆扎带系统。本文的目的是证明这些方法的组合应用如何减少它们各自的缺点。我们的联合方法在两名患者中尝试,一个胫骨开放性骨折,另一个接受了尺神经修复。两名患者在手术后3小时内开始表现出筋膜室综合征的迹象。首先,可吸收的倒钩缝合系统被定位与运行皮内技术。在此之后,插入电缆扎带,并将所讨论的肢体置于升高的位置。患者伤口在2周内完全闭合,无并发症。该结果证明了这些方法的组合与它们单独产生的结果相比的附加益处。
    While fasciotomy is the only urgent treatment option for compartment syndrome, the resulting open wound leaves room for complications. Closure of the wound can be done by different techniques, including split-thickness skin grafts, negative pressure therapy, an absorbable barbed suture system and a cable ties system. The aim of this paper is to demonstrate how a combined application of these methods can reduce their respective individual disadvantages. Our combined method was tried in two patients, one with an open tibial fracture and the other who underwent ulnar nerve reparation. Both patients started exhibiting signs of compartment syndrome within 3 hrs after surgery. Firstly, absorbable barbed suture systems were positioned with the running intradermal technique. Following this the cable ties were inserted and the limb in question was placed in an elevated position. Complete closure of the patient\'s wounds was achieved within 2 weeks without complications. This result is a testament to the added benefit of a combination of these methods in comparison with the results they produce individually.
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  • 文章类型: Case Reports
    方法:我们介绍了一名54岁男子的病例,该男子接受了选择性的髋关节脱节手术,并伴有需要皮肤移植的左肘前窝三度烧伤。经过仔细审查,确定电手术导致的“天线耦合”可能是原因。我们提出了一个实验来证明这种现象。
    结论:天线耦合是一种真实但罕见的术中烧伤原因,此前在骨科文献中没有描述过。应注意避免将bovie或其他电外科器械绳与其他金属绳或有绳器械缠绕或运行。
    METHODS: We present the case of a 54-year-old man who underwent elective hip disarticulation complicated by third-degree burn of the left antecubital fossa requiring skin graft. After careful review, it was determined that \"antenna coupling\" as a result of electrosurgery was the likely cause. We present an experiment demonstrating this phenomenon.
    CONCLUSIONS: Antenna coupling is a real but rare cause of intraoperative burns not previously described in the orthopaedic literature. Care should be taken to avoid coiling or running bovie or other electrosurgical device cords with other metallic cords or corded devices.
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  • 文章类型: Journal Article
    背景:皮肤烧伤通常用自体皮肤移植治疗。植皮后,许多患者抱怨捐赠部位疼痛。供体部位最常见于大腿外侧,由股外侧皮神经(LFCN)支配。LFCN阻断的使用应减少来自供体位点的伤害感受。
    方法:我们的团队于2019年开始使用LFCN模块。利用解剖标志,对所有接受自体皮肤移植的患者进行LFCN阻滞,以减轻围手术期疼痛。对所有接受自体皮肤移植的全身面积烧伤10%或以下的患者进行了回顾性队列研究。从2016年开始的类似队列,在使用任何局部或区域镇痛之前,被用作历史控制。在手术后的每一天至第5天或出院(以先到者为准)收集术后肠内和肠胃外麻醉镇痛药,并转换为吗啡毫克当量(MME)以量化手术后的镇痛。
    结果:图表回顾确定了2020年队列中的55名患者。来自2016年队列的55名患者根据皮肤移植物的大小进行匹配,全身表面积(TBSA)烧伤,性别,和年龄。两组移植物大小无统计学差异,TBSA烧毁,年龄,性别,或烧伤类型。在围手术期(第0-2天)检查麻醉剂使用情况时,我们发现两组的总MME(113vs133,p=0.28)或IVMME(38vs33,p=0.45)没有差异.在延长的术后期间(第1-5天),总MME(149vs.188,t=0.22)或IVMME(37与50,t=0.25)。检查每日麻醉药的使用也没有得出统计学上不同的值。
    结论:我们的数据表明,通过具有里程碑意义的技术使用LFCN阻断并没有减少接受植皮手术的患者的麻醉药使用。未来的研究应该考虑超声引导的LFCN块。
    BACKGROUND: Cutaneous burns are commonly treated with autologous skin grafts. Following skin grafting, many patients complain of pain at the donor site. Donor sites are taken most commonly from the lateral thigh, which is innervated by the lateral femoral cutaneous nerve (LFCN). Use of a LFCN blocks should decrease nociception from the donor site.
    METHODS: Our group began utilizing LFCN blocks in 2019. Utilizing anatomic landmarks, LFCN blocks were performed on all patients who received autologous skin grafts to reduce perioperative pain. A retrospective cohort study was performed on all patients with 10% or less total body surface areas burns who received an autologous skin graft. A similar cohort from 2016, prior to use of any local or regional analgesia, was used as a historical control. Post-operative enteral and parenteral narcotic analgesics were collected for each post-operative day up to day 5 or discharge (whichever came first) and converted to morphine milligram equivalents (MME) to quantify analgesia after surgery.
    RESULTS: Chart review identified 55 patients in the 2020 cohort. Fifty-five patients from the 2016 cohort were matched based upon size of skin graft, total body surface area (TBSA) burned, gender, and age. There were no statistically significant differences between the two groups in terms of size of graft, TBSA burned, age, gender, or type of burn. When examining narcotics usage in the immediate perioperative period (days 0-2), we found no difference between the two groups for total MME (113 vs 133, p = 0.28) or IV MME (38 vs 33, p = 0.45). Similar relationships existed in the extended post-operative period (days 1-5) for total MME (149 vs. 188, t = 0.22) or IV MME (37 vs. 50, t = 0.25). Examining daily narcotic usage also yielded no statistically different values.
    CONCLUSIONS: Our data shows that use of LFCN block by landmark technique did not reduce narcotic usage in patients that undergo skin grafting procedures. Future studies should consider ultrasound-guided LFCN blocks.
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