Sinus Floor Augmentation

窦底增强
  • 文章类型: Journal Article
    目的:这项研究的目的是提出一种综合的上颌窦(MS)轮廓分类系统,该系统基于锥形束计算机断层扫描(CBCT)检查的解剖特征进行评估,并研究鼻窦轮廓与窦底抬高(SFE)之间的关系。
    方法:分析了总共283例上颌骨后牙缺失并接受SFE的CBCT扫描。在每个牙齿位置对MS进行分类。对于颊腭评估,从A型到E的分类是窄锥度,锥度,卵形,正方形,不规则,分别。对于中远端评估,从类型1到类型4的分类是平的,斜坡,凹面,还有隔片,分别。评估的主要解剖参数是(1)残余骨高度(RBH),(2)窦宽度(SW),(3)上颌窦角(MSA),(4)颊倾角(BDA),(5)腭鼻隐窝(PNR),和(6)窦深度。
    结果:经过详细计算,对11组MS等高线进行分类。RBH的差异,MSA,BDA,不同组之间的SW差异有统计学意义。窄锥度和斜率MS(A2)组RBH最高(8.66±0.77mm),最大BDA(79.9°±3.18°),最小MSA(19.8°±2.01°),最窄SW(6.30±1.23mm)。最低的RBH在方形和凹窦(D3)组(5.11±2.70mm)。卵形和凹窦(C3)组的BDA最小(50.64±8.73mm),MSA最大(74.11°±11.52°)。方形和扁平MS(D1)组的SW最宽(19.13±3.69mm)。在SW和MSA之间观察到显着的正相关(r=0.67),在SW和BDA之间观察到显着的负相关(r=-0.65)。PNR的患病率(平均角度:104.06°±16.83°,平均身高:14.72±11.78mm)为38%,在卵形和斜坡MS(C2)组中经常观察到。
    结论:尽管在不同的牙齿部位有某些特征,相同的牙齿位置使用不同的分类系统进行不同的分类,指示MS的大的解剖变异。本文提出的分类系统允许基于单个牙齿部位的一般特征进行分类。旨在帮助外科医生改善术前评估。
    OBJECTIVE: The aim of this study was to propose a comprehensive maxillary sinus (MS) contour classification system based on the evaluation of anatomical characteristics from cone beam computed tomography (CBCT) examination and investigate the relationship between sinus contours and sinus floor elevation (SFE).
    METHODS: A total of 283 CBCT scans from patients who had single tooth loss in the posterior maxilla and underwent SFE were analyzed. The MS was classified at each tooth position. For buccal-palatal evaluation, the classification from Type A to E was narrow-taper, taper, ovoid, square, and irregular, respectively. For mesial-distal evaluation, the classification from Type 1 to 4 was flat, slope, concave, and septa, respectively. The major anatomical parameters evaluated were (1) residual bone height (RBH), (2) sinus width (SW), (3) maxillary sinus angle (MSA), (4) buccal dip angle (BDA), (5) palatonasal recess (PNR), and (6) sinus depth.
    RESULTS: Eleven groups of MS contour were classified after detailed calculation. Differences in the RBH, MSA, BDA, and SW among different groups were statistically significant. The narrow-taper and slope MS (A2) group had the highest RBH (8.66 ± 0.77 mm), largest BDA (79.9° ± 3.18°), smallest MSA (19.8° ± 2.01°), and narrowest SW (6.30 ± 1.23 mm). The lowest RBH was in the square and concave sinus (D3) group (5.11 ± 2.70 mm). The ovoid and concave sinus (C3) group had the smallest BDA (50.64 ± 8.73 mm) and largest MSA (74.11° ± 11.52°). The square and flat MS (D1) group had the widest SW (19.13 ± 3.69 mm). A strongly significant positive correlation was observed between the SW and MSA (r = 0.67) and a strongly negative correlation between the SW and BDA (r = - 0.65). The prevalence of PNR (mean angle: 104.06° ± 16.83°, mean height: 14.72 ± 11.78 mm) was 38% and frequently observed in the ovoid and slope MS (C2) group.
    CONCLUSIONS: Despite certain characteristics at different tooth sites, the same tooth position was categorized differently using different classification systems, indicating large anatomical variations in the MS. The classification system proposed herein allows for classification based on general characteristics at a single tooth site, aiming to help surgeons in improving presurgical evaluation.
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  • 文章类型: Case Reports
    慢性上颌窦炎伴有窦粘膜严重增厚,阻塞口,患者报告的症状需要在上颌窦底增强术(MSFA)前由耳鼻喉科医师进行术前评估和治疗.抗生素处方和鼻腔盐水冲洗是治疗的首选;然而,当治疗效果有限且观察到耐药性时,应考虑鼻内镜手术。然而,据报道,在存在窦道病变的情况下进行的MSFA在正确管理病变时具有良好的结果。本报告介绍了两名需要MSFA但被诊断为慢性上颌窦炎的患者(病例1为鼻窦炎,病例2为牙齿窦炎)。抗生素治疗2周后,由于鼻窦病变的大小变化很小,因此建议进行内窥镜手术;然而,患者因自我报告症状改善而拒绝治疗.因此,计划口内手术引流作为替代治疗.在上颌窦的外侧壁处准备了一个大的骨窗,并进行了长时间的有意切口,以改善抽吸尖端在各个方向和深度进入窦腔的通道。通过该入口进行脓性渗出物的彻底抽吸和盐水冲洗。穿孔区域的大小随着施耐德膜从窦底的抬高而减小,并同时进行植骨与植入物放置。假体在6-8个月后交付。装载后1年随访,观察到植入物存活和维持骨高度增加的有利结果,术后无鼻窦炎复发。在本病例报告的限制范围内,上颌窦底扩张术中彻底的鼻窦引流和盐水冲洗解决了慢性上颌窦炎患者的鼻窦感染,具有短期临床结局.
    Chronic maxillary sinusitis accompanied by severe thickening of the sinus mucosa, blockage of the ostium, and patient-reported symptoms requires preoperative assessment and treatment by an otolaryngologist before maxillary sinus floor augmentation (MSFA). Prescription of antibiotics and nasal saline irrigation are the first choice of treatment; however, endoscopic sinus surgery is considered when the treatment\'s effect is limited and drug resistance is observed. Nevertheless, MSFA performed in the presence of sinus pathologies have been reported to have favorable results when the lesions are managed properly. This report presents cases of two patients who required MSFA but were diagnosed with chronic maxillary sinusitis (case 1 with nasal sinusitis and case 2 with dental sinusitis). After 2 weeks of antibiotic therapy, endoscopic surgery was recommended due to minimal changes in the size of the sinus lesion; however, the patients refused because of improved self-reported symptoms. Therefore, intraoral surgical drainage was planned as an alternative treatment. A large bony window was prepared at the lateral wall of the maxillary sinus, and a long intentional incision was made to improve access for the suction tip in various directions and depths into the sinus cavity. Thorough suction of the purulent exudate and saline irrigation were performed through this access. The size of the perforated area was reduced along with the elevation of the Schneiderian membrane from the sinus floor, and simultaneous bone grafting with implant placement was performed. Prosthesis was delivered after 6-8 months. At 1-year follow-up after loading, favorable outcomes of implant survival and maintenance of augmented bone height were observed, with no recurrence of postoperative sinusitis. Within the limitations of the present case report, thorough sinus drainage and saline irrigation during maxillary sinus floor augmentation resolved sinus infection in patients with chronic maxillary sinusitis with short-term clinical outcomes.
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  • 文章类型: Case Reports
    上颌窦底部强化术(MSA)后发生的并发症可分为早期和晚期并发症。早期并发症是在MSA手术期间或在初始愈合期间发生的副作用。通常,晚期并发症是指MSA治疗3周后出现的副作用.然而,从长远来看,有些病例发生在假体交付后的随访期间,他们中的大多数都有种植体周围炎。在目前的两种情况下,假体移植后1-2年发生了鼻窦移植并发症,但与种植体周围炎无关,并且具有不典型的特征,显示无症状的结果。虽然感染源的途径尚不清楚,据推测,病变是由口腔细菌浸润上颌窦植骨区域的缓慢和迟发性炎症引起的。在目前病例报告的限制范围内,骨缺损通过引导骨再生(GBR)手术成功治疗,包括彻底的缺损脱颗粒,暴露植入物的表面去污,和回归。为了检测鼻窦增强部位的异常鼻窦移植物并发症,需要定期监测放射线图像。
    Complications that occur after maxillary sinus floor augmentation (MSA) can be divided into early and late complications. Early complication is a side effect that occurs during the MSA procedure or during the initial healing period. Usually, late complication refers to a side effect that occurs after 3 weeks of MSA. However, in the longer term, there are cases that occur during the follow-up period after the prosthesis is delivered, and most of them present with peri-implantitis. In the present two cases, sinus graft complications occurred 1-2 years after prosthesis delivery but were independent of peri-implantitis and had atypical features showing asymptomatic results. Although the route of the infection source is unclear, the lesions were presumed to be caused by slow and delayed inflammation of oral bacteria infiltrating the bone graft area of the maxillary sinus. Within the limitations of present case reports, bone defects were successfully managed with a guided bone regeneration (GBR) procedure that included thorough defect degranulation, surface decontamination of exposed implant, and regrafting. Periodic monitoring of radiographic images is required for the detection of unusual sinus graft complications in sinus-augmented sites.
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  • 文章类型: Journal Article
    已经描述了几种用于上颌窦移植物增强的技术,包括侧窗技术和带骨块或骨致密化的椎弓根入路。富含血小板的纤维蛋白由于其加速软组织和硬组织愈合的能力而被用于上颌窦提升手术。这项研究的目的是评估PRF与合成羟基磷灰石NanoBone®结合使用侧窗技术增强窦底抬高骨再生的潜力。在CESPU-Famalicão临床单位的术前评估访视中筛选并在2023年1月至2023年12月期间进行干预的50名患者中,只有6名符合研究纳入标准的患者同意参加。在一项裂口研究中,进行了12次鼻窦移植手术。我们的观察表明,对于测试组(NanoBone®/PRF),有一个27.5±4.9%增加新的重要骨骼,惰性骨颗粒增加23.0±3.7%,结缔组织增加49.4±2.8%。同时,对于对照组(NanoBone®),新的重要骨骼增加19.5±3.0%,惰性骨颗粒增加23.4±5.7%,结缔组织增加57.0±3.5%。结果强烈表明,将液体PRF与NanoBone®混合不会对活骨形成量产生负面影响,与单次使用NanoBone®相比,使用外侧窗技术的鼻窦植骨手术中的新骨形成和血运重建似乎略有增加。
    Several techniques have been described for maxillary sinus graft augmentation, including the lateral window technique and crestal approach with osteotomes or osseodensification. Platelet-rich fibrin has been used in maxillary sinus lift procedures due to its ability to accelerate soft and hard tissue healing. The aim of this study was to evaluate the potential of PRF in combination with the synthetic hydroxyapatite NanoBone® to enhance bone regeneration in sinus floor elevation with the lateral window technique. Out of the 50 individuals screened in a preoperative assessment visit from the CESPU-Famalicão clinical unit and intervened upon between January 2023 and December 2023, only 6 patients who met the study\'s inclusion criteria consented to participate. In a split-mouth study, twelve sinus graft surgeries were carried out. Our observations reveal that for the test group (NanoBone®/PRF), there is a 27.5 ± 4.9% increase new vital bone, 23.0 ± 3.7% increase in inert bone particles, and 49.4 ± 2.8% increase in connective tissue. Meanwhile, for the control group (NanoBone®), there is a 19.5 ± 3.0% increase in new vital bone, 23.4 ± 5.7% increase in inert bone particles, and 57.0 ± 3.5% increase in connective tissue. The results strongly indicate that mixing liquid PRF with NanoBone® does not have a negative influence on the amount of viable bone formation, and it seems to slightly increase the amount of new bone formation and revascularization in sinus bone graft procedures with the lateral window technique compared to the single use of NanoBone®.
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  • 文章类型: Case Reports
    上颌骨后段的长期部分性牙本质症是一种具有挑战性的治疗方法,通常涉及广泛而侵入性的窦底增强术。各种方法已被用于窦底抬高,包括使用气球技术的液压应用。该病例报告描述了一种改良的膨胀技术,该技术使用Foley导管升高窦底,以在放置骨移植物和骨内植入物之前应用液压方法升高Schneiderian膜。在拔出的左第一上颌磨牙区域出现萎缩性牙槽脊高度为3.0mm的37岁男性患者。使用Foley导管的窦底抬高导致窦底抬高7mm,牙槽骨高度增加7.8mm。在假体植入物装载后的一年随访期间,患者无症状,植入物稳定。
    Longstanding partial edentulism in the posterior segment of the maxilla is a challenging treatment and typically involves extensive and invasive sinus floor augmentation. Various methods have been employed for sinus floor elevation, including the application of hydraulic pressure using the balloon technique. This case report describes a modified ballooning technique to elevate the sinus floor using a Foley catheter to apply the hydraulic pressure method to elevate the Schneiderian membrane prior to the placement of bone grafts and an endosseous implant in a 37-year-old male patient who presented with an atrophic alveolar ridge height of 3.0 mm in the area of the extracted left first maxillary molar. Sinus floor elevation using the Foley catheter led to a sinus floor elevation of 7 mm and a gain in alveolar bone height of 7.8 mm. The patient was asymptomatic with a stable implant during the one-year follow-up period after prosthetic implant loading.
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  • 文章类型: Journal Article
    自体牙本质基质(ADM),从病人拔下的牙齿中提取出来,可以在重建牙科中用作自体移植材料。提取的牙齿为ADM提供了来源,以其低拒绝率而著称,骨诱导能力和易于制备。因此,它提供了一个可行的替代自体骨。动物研究证实了其有效的骨诱导特性,虽然其临床应用包括提取后部位保存,上颌窦底增强术,并引导骨组织再生。然而,ADM应用于骨再生的长期疗效仍未得到充分开发,并且在制备过程中缺乏标准化。本文全面探讨了作文,骨诱导性的潜在机制,制备方法,和ADM的临床应用,目的是为该主题的未来研究建立基本参考。
    Autogenous dentin matrix (ADM), derived from a patient\'s extracted tooth, can be repurposed as an autologous grafting material in reconstructive dentistry. Extracted teeth provide a source for ADM, which distinguishes itself with its low rejection rate, osteoinductive capabilities and ease of preparation. Consequently, it presents a viable alternative to autogenous bone. Animal studies have substantiated its effective osteoinductive properties, while its clinical applications encompass post-extraction site preservation, maxillary sinus floor augmentation, and guided bone tissue regeneration. Nevertheless, the long-term efficacy of ADM applied in bone regeneration remains underexplored and there is a lack of standardization in the preparation processes. This paper comprehensively explores the composition, mechanisms underlying osteoinductivity, preparation methods, and clinical applications of ADM with the aim of establishing a fundamental reference for future studies on this subject.
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  • 文章类型: Journal Article
    这项系统综述和荟萃分析旨在提供详细的见解,以了解与骨增强同时放置的较短和较长的牙科植入物的临床表现。
    在MEDLINE(PubMed)上进行了文献搜索,ScienceDirect和Cochrane图书馆数据库,遵守特定的选择标准和系统审查和荟萃分析(PRISMA)指南的首选报告项目。只有2014年至2024年之间以英文发表的文章才被考虑用于数据收集。主要结果是生存率(SR),边缘骨丢失(MBL)和并发症。临床结果如下:探查出血(BOP),牙周袋深度(PPD),和植入物稳定性商(ISQ)。通过JoannaBriggs研究所开发的随机对照试验的关键评估清单工具评估偏倚评估的质量和风险。
    共筛选了14678篇文章,9符合纳入标准,并被用于本系统综述和荟萃分析。共有495名患者使用984个植入物(491个短植入物和493个较长植入物),短植入物的SR为93.91%,较长植入物的SR为91.83%。荟萃分析显示,同时放置牙槽骨增强的短植入物和长植入物与MBL之间存在统计学上的显着差异(-0.513mm,95%CI=-0.93至-0.096;P=0.02),和PPD(-0.247,95%CI=-0.515至0.022;P=0.07)。
    当比较短和更长的牙科植入物结合牙槽骨增强的治疗结果时,短植入物在存活率参数方面显示出更好的临床结果,边缘骨丢失和并发症。
    UNASSIGNED: This systematic review and meta-analysis aim to provide detailed insights into the clinical performance of short and longer dental implants placed simultaneously with bone augmentation.
    UNASSIGNED: The search for literature was performed across MEDLINE (PubMed), ScienceDirect and the Cochrane Library databases, adhering to specific selection criteria and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Only articles published in English between 2014 and 2024 were considered for data collection. Primary outcomes were survival rate (SR), marginal bone loss (MBL) and complications. Clinical outcomes were as follows: bleeding on probing (BOP), periodontal pocket depth (PPD), and implant stability quotient (ISQ). Quality and risk of bias assessment were evaluated by the Critical Appraisal Checklist tool for randomized controlled trials developed by the Joanna Briggs Institute.
    UNASSIGNED: A total of 14678 articles were screened, with 9 meeting the inclusion criteria and being utilized for this systematic review and meta-analysis. A total of 495 patients with 984 implants (491 short and 493 longer implants) showing a SR of 93.91% for the short implants and 91.83% for the longer implants. Meta-analysis revealed statistically significant difference between short implants and longer implants simultaneously placed with alveolar bone augmentation in relation to MBL (-0.513 mm, 95% CI = -0.93 to -0.096; P = 0.02), and in PPD (-0.247, 95% CI = -0.515 to 0.022; P = 0.07).
    UNASSIGNED: When comparing the results of treatment with short and longer dental implants combined with alveolar bone augmentation, short implants showed better clinical results regarding the parameters of survival rate, marginal bone loss and complications.
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  • 文章类型: Journal Article
    背景:由于骨骼质量差以及垂直骨高度的损失,上颌骨后部对植入物插入提出了挑战。当需要增加几毫米的高度时,建议采用间接的经齿窦提升技术。这项研究旨在评估窦膜球囊技术与Densahburs在同时放置植入物的情况下进行经颌骨上颌窦提升的临床和影像学结果。
    方法:这项随机临床试验是对22例患者进行的,这些患者接受了32次牙种植体,用于在上颌窦抬升后替换错过的上颌后牙。将患者随机分为两组。第1组,患者使用窦膜球囊技术同时进行植入植入,同时进行窦底抬高。第2组,患者使用Densahburs同时进行植入物植入,同时进行了窦底抬高。立即定期使用锥形束计算机断层扫描(CBCT)对患者进行临床和影像学评估,术后6个月和12个月。对所有临床和影像学参数进行统计分析。
    结果:所有牙种植体均成功,随访12个月。关于植入物的主要稳定性,有统计学上的显著差异,有利于Densah组(P=0.004),6个月后差异无统计学意义(P=0.07)。射线照相,球囊组术后即刻垂直骨高度有统计学意义(P<0.0001),6个月后垂直骨高度显著降低(P<0.0001)。Densah组骨密度显著增加(P≤0.05)。
    结论:两种技术均显示出成功的临床和影像学结果。窦膜球囊组表现出更好的术后即刻垂直骨增益,而DensahBurs具有较高的种植体初级稳定性和骨密度。
    背景:本研究已在Clinical-Trials.govPRS(https://register。
    结果:gov),ID号为NCT05922592,日期为2023年6月28日。
    BACKGROUND: The posterior maxilla presents challenges for implant insertion because of the poor bone quality as well as the loss of vertical bone height. Indirect transcrestal sinus lift techniques are advised when a few millimeters of additional height are needed. This study aimed to evaluate the clinical and radiographic outcomes of antral membrane balloon technique versus Densah burs for transcrestal maxillary sinus lifting with simultaneous implant placement.
    METHODS: This randomized clinical trial was conducted on 22 patients received 32 dental implants for replacement of missed maxillary posterior teeth after crestal maxillary sinus lifting. The patients were randomly divided into two groups. Group 1, patients underwent crestal sinus floor elevation with simultaneous implant placement using antral membrane balloon technique. Group 2, patients underwent crestal sinus floor elevation with simultaneous implant placement using Densah burs. Patients were evaluated clinically and radiographically using cone beam computed tomography (CBCT) at regular time intervals immediately, 6 months and 12 months after surgery. All clinical and radiographic parameters were statistically analyzed.
    RESULTS: All dental implants were successful for 12 months of follow up. Regarding implant primary stability, there was a statistical significant difference between the study groups in favor of Densah group (P = 0.004), while there was no significant difference after 6 months (P = 0.07). Radiographically, balloon group showed a statistically significant immediate postoperative vertical bone height (P < 0.0001), and significant reduction in vertical bone height after 6 months (P < 0.0001). Densah group showed significant increase in bone density (P ≤ 0.05).
    CONCLUSIONS: Both techniques demonstrated successful clinical and radiographic outcomes for crestal sinus lift. The antral membrane balloon group demonstrated better immediate postoperative vertical bone gain, while Densah burs had higher implant primary stability and bone density.
    BACKGROUND: This study was registered in Clinical-Trials.gov PRS ( https://register.
    RESULTS: gov ) under identification number NCT05922592 on 28/06/2023.
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  • 文章类型: Journal Article
    目的:鼻窦膜穿孔是隆窦手术的常见并发症。这篇综述旨在研究解剖因素,如隔膜的存在和侧壁厚度,是否会影响膜穿孔的风险。
    方法:本研究注册于PROSPERO(CRD42023488259)。PubMed,Embase,搜索了截至2024年6月26日发表的相关研究。感兴趣的结果是基于隔片和侧壁厚度的穿孔风险。使用二元数据进行随机效应荟萃分析,以使用ReviewManager获得穿孔的比值比(OR)。
    结果:纳入了10项研究,其中1865例患者接受了2168个“外侧”鼻窦提升手术。Schneiderian膜穿孔的总发生率为19%(405例)。有鼻窦隔片169/425例(39.76%),无隔片184/1492例(12.33%)存在Schneider膜穿孔。Meta分析显示,隔片与穿孔风险增加显著相关(OR:4.0395%CI:1.77,9.19),异质性高(I2=87%)。证据的确定性很低。关于侧壁厚度和穿孔风险的数据在荟萃分析中过于异质。研究报告了基于侧壁厚度的穿孔风险的混合结果。
    结论:我们的结果表明,质量很低的证据,在上颌窦提升手术中,隔膜的存在显着增加了穿孔的风险。关于鼻窦提升手术中侧壁厚度与穿孔风险之间的关联的证据是相互矛盾的,现阶段还不能得出明确的结论。
    OBJECTIVE: Sinus membrane perforation is a common complication of sinus lift surgery. This review aimed to examine if anatomical factors such as the presence of septa and lateral wall thickness influence the risk of membrane perforation.
    METHODS: This study was registered on PROSPERO (CRD42023488259). PubMed, Embase, and Web of Science were searched for relevant studies published up to 26th June 2024. The outcome of interest was the risk of perforation based on presence of septa and lateral wall thickness. Random-effects meta-analysis was conducted with dichotomous data to obtain the odds ratio (OR) of perforation using Review Manager.
    RESULTS: Ten studies with 1865 patients undergoing 2168 \"lateral\" sinus lift procedures were included. The total incidence of Schneiderian membrane perforations was 19% (405 cases). Schneiderian membrane perforation was present in 169/425 cases (39.76%) with sinus septa and 184/1492 cases (12.33%) without septa. Meta-analysis showed that septa were significantly associated with an increased risk of perforation (OR: 4.03 95% CI: 1.77, 9.19) with high heterogeneity (I2 = 87%). The certainty of the evidence was very low. Data on lateral wall thickness and risk of perforation was too heterogeneous for a meta-analysis. Studies reported mixed results on the risk of perforation based on lateral wall thickness.
    CONCLUSIONS: Our results show, with very low-quality evidence, that the presence of septa significantly increases the risk of perforations during maxillary sinus lift surgery. Evidence on the association between lateral wall thickness and a risk of perforations during sinus lift surgery is conflicting, and no clear conclusions can be derived at this stage.
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  • 文章类型: Journal Article
    背景:抗血小板和抗凝药物对窦底扩张术结果的影响尚不清楚。
    方法:这项回顾性队列研究分析了在单个医疗中心接受窦底扩张术的连续患者的电子病历数据。患者分为三类:接受抗血小板药物治疗的患者,接受抗凝药物治疗的患者,和健康的个体。收集的数据包括吸烟,残余牙槽骨高度,植入物放置的时机,使用的材料,垂直骨增益,早期植入失败(EIF),和并发症如Schneiderian膜穿孔和术后出血。进行多变量分析以评估EIF的危险因素。统计显著性被认为低于5%。
    结果:在110例患者中,有305个植入物,EIF发生在10%的患者和4.65%的植入物中。研究组之间在术后出血或EIF方面没有发现显着差异。单变量和多变量分析强调吸烟(优势比[OR]=7.92),下残余牙槽脊高度(OR=0.81),分期植入(OR=4.64)是该队列中重要的EIF危险因素。
    结论:抗凝和抗血小板治疗并没有显著增加EIF或窦底扩张术后出血的风险。吸烟,在使用抗血小板或抗凝药物进行窦底扩张的患者中,残余牙槽沟高度和分期窦底扩张是发生EIF的危险因素.
    BACKGROUND: The effect of antiplatelet and anticoagulant medications on the outcomes of sinus floor augmentation remains unclear.
    METHODS: This retrospective cohort study analyzed data from electronic medical records of consecutive patients undergoing sinus floor augmentation at a single medical center. Patients were categorized into three categories: patients under antiplatelet medications, patients under anticoagulation medications, and healthy individuals. Data collected included tobacco smoking, residual alveolar bone height, timing of implant placement, materials used, vertical bone gain, early implant failure (EIF), and complications such as Schneiderian membrane perforation and postoperative bleeding. Multivariable analysis was performed to assess risk factors for EIF. Statistical significance was considered below 5%.
    RESULTS: Among 110 patients with 305 implants, EIF occurred in 10% of patients and 4.65% of implants. No significant difference in postoperative bleeding or EIF was found between study groups. Univariate and multivariable analyses highlighted tobacco smoking (odds ratio [OR] = 7.92), lower residual alveolar ridge height (OR = 0.81), and staged implant placement (OR = 4.64) as significant EIF risk factors in this cohort.
    CONCLUSIONS: Anticoagulant and antiplatelet therapies do not significantly elevate the risk of EIF or postoperative bleeding following sinus floor augmentation. Tobacco smoking, residual alveolar ridge height and staged sinus floor augmentation were risk factors for EIF in patients using antiplatelet or anticoagulation medications undergoing sinus floor augmentation.
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