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  • 文章类型: Journal Article
    磁共振已成为各种临床场景中的一线成像模态。使用不同心血管装置的患者数量,包括心脏可植入电子设备,呈指数增长。尽管有报道称这些患者存在与磁共振暴露相关的风险,现在的临床证据支持在特定条件下进行这些研究的安全性,并遵循建议以最小化可能的风险.本文件由西班牙心脏病学会(SEC-GTCRMTC)心脏磁共振成像和心脏计算机断层扫描工作组撰写,西班牙心脏病学会心律协会(SEC-心律协会),西班牙医学放射学会(SERAM),和西班牙心胸成像学会(SEICAT)。该文件回顾了该领域可用的临床证据,并建立了一系列建议,以便具有心血管设备的患者可以安全地使用此诊断工具。
    Magnetic resonance has become a first-line imaging modality in various clinical scenarios. The number of patients with different cardiovascular devices, including cardiac implantable electronic devices, has increased exponentially. Although there have been reports of risks associated with exposure to magnetic resonance in these patients, the clinical evidence now supports the safety of performing these studies under specific conditions and following recommendations to minimize possible risks. This document was written by the Working Group on Cardiac Magnetic Resonance Imaging and Cardiac Computed Tomography of the Spanish Society of Cardiology (SEC-GT CRMTC), the Heart Rhythm Association of the Spanish Society of Cardiology (SEC-Heart Rhythm Association), the Spanish Society of Medical Radiology (SERAM), and the Spanish Society of Cardiothoracic Imaging (SEICAT). The document reviews the clinical evidence available in this field and establishes a series of recommendations so that patients with cardiovascular devices can safely access this diagnostic tool.
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  • 文章类型: Journal Article
    磁共振已成为各种临床场景中的一线成像模态。使用不同心血管装置的患者数量,包括心脏可植入电子设备,呈指数增长。尽管有报道称这些患者存在与磁共振暴露相关的风险,现在的临床证据支持在特定条件下进行这些研究的安全性,并遵循建议以最小化可能的风险.本文件由西班牙心脏病学会(SEC-GTCRMTC)心脏磁共振成像和心脏计算机断层扫描工作组撰写,西班牙心脏病学会心律协会(SEC-心律协会),西班牙医学放射学会(SERAM),和西班牙心胸成像学会(SEICAT)。该文件回顾了该领域可用的临床证据,并建立了一系列建议,以便具有心血管设备的患者可以安全地使用此诊断工具。英文全文可查阅:www.revespcardiol.org/en。
    Magnetic resonance has become a first-line imaging modality in various clinical scenarios. The number of patients with different cardiovascular devices, including cardiac implantable electronic devices, has increased exponentially. Although there have been reports of risks associated with exposure to magnetic resonance in these patients, the clinical evidence now supports the safety of performing these studies under specific conditions and following recommendations to minimize possible risks. This document was written by the Working Group on Cardiac Magnetic Resonance Imaging and Cardiac Computed Tomography of the Spanish Society of Cardiology (SEC-GT CRMTC), the Heart Rhythm Association of the Spanish Society of Cardiology (SEC-Heart Rhythm Association), the Spanish Society of Medical Radiology (SERAM), and the Spanish Society of Cardiothoracic Imaging (SEICAT). The document reviews the clinical evidence available in this field and establishes a series of recommendations so that patients with cardiovascular devices can safely access this diagnostic tool.
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  • 文章类型: Journal Article
    背景:Alemtuzumab是一种被欧洲药品管理局批准为用于治疗复发缓解型多发性硬化症的疾病缓解药物的高效药物。
    目的:起草了一份关于阿仑珠单抗在西班牙常规临床实践中的管理的共识文件。
    方法:一组多发性硬化症专家回顾了2017年12月之前发表的关于阿仑珠单抗治疗多发性硬化症患者的文章。纳入的研究评估了药物的疗效,有效性,和安全性;筛查感染和疫苗接种;以及管理和监测方面。最初提出的建议是由协调小组根据现有证据及其临床经验制定的。协商一致进程分两个阶段进行,集团协议的初始阈值百分比为80%。载有工作组商定的所有建议的最后文件已提交外部审查,协调小组对收到的意见进行了审议。
    结论:本文件旨在用作在常规临床实践中优化阿仑珠单抗管理的工具。
    BACKGROUND: Alemtuzumab is a highly effective drug approved by the European Medicines Agency as a disease-modifying drug for the treatment of relapsing-remitting multiple sclerosis.
    OBJECTIVE: A consensus document was drafted on the management of alemtuzumab in routine clinical practice in Spain.
    METHODS: A group of multiple sclerosis specialists reviewed articles addressing treatment with alemtuzumab in patients with multiple sclerosis and published before December 2017. The included studies assessed the drug\'s efficacy, effectiveness, and safety; screening for infections and vaccination; and administration and monitoring aspects. The initial proposed recommendations were developed by a coordinating group and based on the available evidence and their clinical experience. The consensus process was carried out in 2 stages, with the initial threshold percentage for group agreement established at 80%. The final document with all the recommendations agreed by the working group was submitted for external review and the comments received were considered by the coordinating group.
    CONCLUSIONS: The present document is intended to be used as a tool for optimising the management of alemtuzumab in routine clinical practice.
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  • 文章类型: Journal Article
    SARS-CoV-2大流行的现状使我国许多医院的非紧急和/或肿瘤外科瘫痪,这对等待外科手术的公民的健康意味着什么。门诊手术可以提供在外科部门进行的超过85%的外科手术,并且目前被认为是可行且安全的替代方案,因为它不需要入院并明显降低了感染的风险。此外,这是应该推广的工具,以解决大流行正在产生的等待名单上的患者积累,因此,西班牙外科医生协会的门诊外科部门提出了一系列建议,以在我们必须生活的这些特殊情况下实施门诊手术。
    The current situation of the SARS-CoV-2 pandemic has paralyzed non-urgent and/or oncological surgery in many hospitals in our country with what it means for the health of citizens who are awaiting a surgical procedure. Outpatient Surgery can afford more than 85% of the surgical procedures that are performed in a surgical department and is presented as a feasible and safe alternative at the present time since it does not require admission and decreases clearly the risk of infection. In addition, it is the tool that should be generalized to solve the accumulation of patients on the waiting list that the pandemic is generating, so it seems appropriate that the Ambulatory Surgery section of the Spanish Association of Surgeons present a series of recommendations for the implementation of outpatient surgery in these exceptional circumstances that we have to live.
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  • 文章类型: Journal Article
    SARS-CoV-2大流行的现状使我国许多医院的非紧急和/或肿瘤外科瘫痪,这对等待外科手术的公民的健康意味着什么。门诊手术可以提供在外科部门进行的超过85%的外科手术,并且目前被认为是可行且安全的替代方案,因为它不需要入院并明显降低了感染的风险。此外,这是应该推广的工具,以解决大流行正在产生的等待名单上的患者积累,因此,西班牙外科医生协会的门诊外科部门提出了一系列建议,以在我们必须生活的这些特殊情况下实施门诊手术。
    The current situation of the SARS-CoV-2 pandemic has paralyzed non-urgent and/or oncological surgery in many hospitals in our country with what it means for the health of citizens who are awaiting a surgical procedure. Outpatient Surgery can afford more than 85% of the surgical procedures that are performed in a surgical department and is presented as a feasible and safe alternative at the present time since it does not require admission and decreases clearly the risk of infection. In addition, it is the tool that should be generalized to solve the accumulation of patients on the waiting list that the pandemic is generating, so it seems appropriate that the Ambulatory Surgery section of the Spanish Association of Surgeons present a series of recommendations for the implementation of outpatient surgery in these exceptional circumstances that we have to live.
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  • 文章类型: Journal Article
    Alemtuzumab是欧洲药品管理局批准的一种高效药物,可作为治疗复发缓解型多发性硬化症的疾病缓解药物。
    在西班牙的常规临床实践中起草了一份关于阿仑珠单抗管理的共识文件。
    一组多发性硬化症专家回顾了关于阿仑妥珠单抗治疗多发性硬化症患者的文章,并在2017年12月之前发表。纳入的研究评估了药物的疗效,有效性,和安全性;筛查感染和疫苗接种;以及管理和监测方面。最初提出的建议是由协调小组根据现有证据及其临床经验制定的。协商一致进程分两个阶段进行,集团协议的初始阈值百分比为80%。载有工作组商定的所有建议的最后文件已提交外部审查,协调小组对收到的意见进行了审议。
    本文件旨在用作在常规临床实践中优化阿仑单抗管理的工具。
    Alemtuzumab is a highly effective drug approved by the European Medicines Agency as a disease-modifying drug for the treatment of relapsing-remitting multiple sclerosis.
    A consensus document was drafted on the management of alemtuzumab in routine clinical practice in Spain.
    A group of multiple sclerosis specialists reviewed articles addressing treatment with alemtuzumab in patients with multiple sclerosis and published before December 2017. The included studies assessed the drug\'s efficacy, effectiveness, and safety; screening for infections and vaccination; and administration and monitoring aspects. The initial proposed recommendations were developed by a coordinating group and based on the available evidence and their clinical experience. The consensus process was carried out in 2 stages, with the initial threshold percentage for group agreement established at 80%. The final document with all the recommendations agreed by the working group was submitted for external review and the comments received were considered by the coordinating group.
    The present document is intended to be used as a tool for optimising the management of alemtuzumab in routine clinical practice.
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  • 文章类型: Journal Article
    BACKGROUND: The intravesical administration of hazardous drug products is a standard practice in the urology setting, which potentially exposing medical personnel to these drug products. It was deemed necessary to have a consensus document among the scientific societies involved (the Spanish Urological Association and the Spanish Society of Hospital Pharmacy) that collects the best available evidence on the safest handling possible of dangerous drug products in the setting of urology departments.
    METHODS: We reviewed the legislation and recommendations on the handling of dangerous drug products, both at the national and international level.
    RESULTS: There is national legislation and regulations for protecting workers who handle dangerous drugs and products, as well as recommendations for handling to protect both the product and workers.
    CONCLUSIONS: Following the strategic lines of the European Parliament for 2014-2020 in the chapter on occupational safety and health, the Spanish Urological Association and the Spanish Society of Hospital Pharmacy proposed a series of actions that decrease the risks of exposure for practitioners and caregivers involved in the handling of these products.
    CONCLUSIONS: After this review, 19 recommendations were established for handling dangerous drug products, which can be summarised as the need to train all individuals involved (from management teams to patients and caregivers), adopt systems that prevent contaminating leaks, implement exposure surveillance programmes and optimise available resources.
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