香雷醇,从草药和风味植物鼠尾草(SalviasclareaL.)中分离出的二萜醇,作为丹参精炼油中的主要成分而闻名(L.).丹参的经验医学专注于各种疾病,比如关节炎,口腔炎症,消化系统疾病,而香雷醇具有更广泛和特征性的生物活性,包括抗肿瘤,抗炎和抗病原微生物,甚至抗糖尿病和高血压。然而,根据有据可查的研究,缺乏文献来整合和阐明香雷酚的药理特性。有趣的是,克拉雷醇最近被认为是对抗COVID-19和帕金森病的潜在候选药物。因此,克拉雷醇在癌症中的生物活性属性,炎症,甚至对药物化学和给药系统进行了综述,以全面剖析其在医学中的潜在应用。
Sclareol, a diterpene alcohol isolated from the herbal and flavor plant clary sage (Salvia sclarea L.), is far-famed as the predominant ingredient in the refined oil of Salvia sclarea (L.). The empirical medicine of Salvia sclarea L. focused on various diseases, such as arthritis, oral inflammation, digestive system diseases, whereas the
sclareol possessed more extensive and characteristic bioactivities, including anti-tumor, anti-inflammation and anti-pathogenic microbes, even anti-diabetes and hypertension. However, there is a deficiency of literature to integrate and illuminate the pharmacological attributes of
sclareol based on well-documented investigations. Interestingly,
sclareol has been recently considered as the potential candidate against COVID-19 and Parkinson\'s disease. Accordingly, the bioactive attributes of
sclareol in cancer, inflammation, even pharmacochemistry and delivery systems are reviewed for comprehensively dissecting its potential application in medicine.