背景:目前尚无治疗中心性离心瘢痕性脱发(CCCA)的既定护理标准,治疗方法差异很大。
目的:就使用各种药物治疗CCCA成人达成共识。
方法:我们邀请了27位在头发和头皮疾病方面具有专业知识的皮肤科医生参加了2023年1月至3月之间的3轮改良Delphi研究。如果75%的受访者同意或不同意,则声明会达成强烈共识。如果55%或更多但不到75%同意或不同意,则声明达到中等共识。
结果:在第1轮中,33个陈述中的第5个(15.2%)达成了强烈共识,其次是第二轮28人中的9人(32.1%)。在最后的第3轮会议之后,70份总体声明中有20份(28.6%)达成了强烈共识。两个声明达成了适度的共识。
结论:这项研究仅包括讲英语的人,美国皮肤科医生,不考虑非药物治疗。
结论:尽管皮肤科医生意见不一,就帮助临床医师管理CCCA的若干声明达成共识.我们还强调缺乏专家共识的领域,以推进CCCA的研究和治疗方案为目标。
BACKGROUND: There is no established standard of care for treating central centrifugal cicatricial alopecia (CCCA), and treatment approaches vary widely.
OBJECTIVE: To develop consensus statements regarding the use of various pharmacological therapies in treating adults with CCCA.
METHODS: We invited 27 dermatologists with expertise in hair and scalp disorders to participate in a 3-round modified Delphi study between January and March 2023. Statements met strong
consensus if 75% of respondents agreed or disagreed. Statements met moderate
consensus if 55% or more but less than 75% agreed or disagreed.
RESULTS: In round 1, 5 of 33 (15.2%) statements met strong
consensus, followed by 9 of 28 (32.1%) in round 2. After the final round 3 meeting, strong
consensus was reached for 20 of 70 (28.6%) overall statements. Two statements achieved moderate
consensus.
CONCLUSIONS: This study included only English-speaking, US-based dermatologists and did not consider nonpharmacological therapies.
CONCLUSIONS: Despite varying opinions among dermatologists, consensus was reached for several statements to help clinicians manage CCCA. We also highlight areas that lack expert consensus with the goal of advancing research and therapeutic options for CCCA.