Risk assessments

风险评估
  • 文章类型: Journal Article
    社区护理包括客户和医疗保健提供者的固有风险。为提供护理服务保持安全的环境可确保将无意或故意人身伤害的风险降至最低。此范围审查的目的是(a)通过总结当前文献来提供现有知识的概述,以及(b)确定与理解和管理社区护理环境风险有关的差距。在人口/概念/背景方法和PRISMA指南的指导下,本文使用两个问题来回答如何开发基于评分的社区护理服务对象适用性评估工具,以及环境筛查工具如何帮助降低社区护理工作者的风险.CINAHL的文献检索,PubMed(Medline),WebofScience和PsychINFO数据库是在2023年9月至2023年11月之间进行的。我们收录了2018年至2023年发表的全文文章。以下四个广泛领域被确定为环境筛选工具结构中的关键组成部分:环境因素,健康因素,社会经济因素和文化因素。这项审查的结果提供了有价值的信息,可以被护理组织用来开发和/或完善工具,以确保社区护理部门工人的安全和福祉。
    Community care encompasses inherent risks for both clients and healthcare providers. Maintaining a safe environment for the delivery of care services ensures that any risk of unintentional or intentional personal harm is minimised. The aim of this scoping review is to (a) provide an overview of existing knowledge by summarising the current literature and (b) identify gaps pertaining to understanding and managing environmental risk in community care settings. Guided by the Population/Concept/Context approach and PRISMA guidelines, this paper used two questions to answer how a score-based tool for assessing client suitability in community care is developed and how an environmental screening tool assists with reducing risk to community care workers. Literature searches of CINAHL, PubMed (Medline), Web of Science and PsychINFO databases were conducted between September 2023 and November 2023. We included full text articles published from 2018 to 2023. The following four broad areas were identified as key components in the structure of an environmental screening tool: environmental factors, health factors, socioeconomic factors and cultural factors. The results of this review provide valuable information which can be utilised by care organisations to develop and/or refine tools to ensure the safety and wellbeing of workers within the community care sector.
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  • 文章类型: Journal Article
    生物碱已被人类利用多年。它们在药物中具有不同的应用。它们已被证明可有效治疗多种疾病。它们也是人类常规饮食的重要组成部分,因为它们存在于食品中,食品补充剂,饮食成分和食物污染物。尽管它们明显的重要性,这些生物碱对人类是有毒的。它们的毒性取决于一系列因素,例如特定剂量,暴露时间和个人属性。轻微的毒性作用包括恶心,瘙痒和呕吐,而慢性影响包括瘫痪,致畸性和死亡。这篇综述总结了已发表的关于毒性的研究,分析方法,存在于食物中的六个主要生物碱组的发生和风险评估,即,麦角,配糖生物碱,嘌呤,吡咯烷嗪,喹啉嗪和托烷生物碱。
    Alkaloids have been utilized by humans for years. They have diverse applications in pharmaceuticals. They have been proven to be effective in treating a number of diseases. They also form an important part of regular human diets, as they are present in food items, food supplements, diet ingredients and food contaminants. Despite their obvious importance, these alkaloids are toxic to humans. Their toxicity is dependent on a range of factors, such as specific dosage, exposure time and individual properties. Mild toxic effects include nausea, itching and vomiting while chronic effects include paralysis, teratogenicity and death. This review summarizes the published studies on the toxicity, analytical methods, occurrence and risk assessments of six major alkaloid groups that are present in food, namely, ergot, glycoalkaloids, purine, pyrrolizidine, quinolizidine and tropane alkaloids.
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  • 文章类型: Journal Article
    这项研究的目的是在全球范围内评估瓶装饮用水中无机和有机物质以及微生物污染物的含量。研究结果与世卫组织指南进行了比较,EPA标准,欧洲联盟(欧盟)指令,和国际瓶装水协会(IBWA)起草的标准。我们的评论显示,46%的研究集中在有机污染物上,25%的物理化学参数,12%的微量元素,7%对微生物质量、10%的微塑料(MPs)和放射性核素元素。总的来说,从54项针对有机污染物(OCs)化合物的研究中,11%的研究显示OCs浓度高于标准允许限值。根据本综述获得的结果,几个OC,无机污染物(IOC),包括CHCl3、CHBrCl2、DEHP、苯,苯乙烯,Ba,As,Hg,pb,Ag,F,一些国家的瓶装饮用水中的NO3和SO4高于国际准则值,这可能在很长一段时间内对人类健康造成风险。此外,一些具有已知或未知健康影响的有问题的污染物,如EDC,DBP,AA,议员们,某些放射性核素(40K和222Rn)缺乏国际准则规定的瓶装饮用水的最大允许值。OCs和IOCs的风险指数(HI)(CHBrCl2,Ba,As,和Hg)在成人和儿童中高于1,儿童CHCl3的HI值大于1。因此,需要进一步研究才能更好地了解瓶装饮用水中的所有污染物水平。
    The aim of this study was to evaluate the levels of inorganic and organic substances as well as microbial contaminants in bottled drinking water on a global scale. The findings were compared to WHO guidelines, EPA standards, European Union (EU) directive, and standards drafted by International Bottled Water Association (IBWA). Our review showed that 46% of studies focused on the organic contaminants, 25% on physicochemical parameters, 12% on trace elements, 7% on the microbial quality, and 10% on microplastics (MPs) and radionuclides elements. Overall, from the 54 studies focusing on organic contaminants (OCs) compounds, 11% of studies had higher OCs concentrations than the standard permissible limit. According to the obtained results from this review, several OCs, inorganic contaminants (IOCs), including CHCl3, CHBrCl2, DEHP, benzene, styrene, Ba, As, Hg, pb, Ag, F, NO3, and SO4 in bottled drinking water of some countries were higher than the international guidelines values that may cause risks for human health in a long period of time. Furthermore, some problematic contaminants with known or unknown health effects such as EDCs, DBP, AA, MPs, and some radionuclides (40K and 222Rn) lack maximum permissible values in bottled drinking water as stipulated by international guidelines. The risk index (HI) for OCs and IOCs (CHBrCl2, Ba, As, and Hg) was higher than 1 in adults and children, and the value of HI for CHCl3 in children was more than 1. Thus, further studies are required to have a better understanding of all contaminants levels in bottled drinking water.
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  • 文章类型: Journal Article
    Difficult airway is a clinical situation in which a trained anesthesiologist experiences trouble with facemask ventilation and/or laryngoscopy and/or intubation. Poor identification of at-risk patients has been identified as one of the causes of difficult airway management.
    We aimed to review the literature regarding the use of wristbands to identify adult patients with known or predicted difficult airway in hospitals.
    We searched Web of Science (WoS), Scopus, MEDLINE and OVID following the stages described by the PRISMA Extension for Scoping Reviews (PRISMA-ScR). We used a combination of MeSH terms and non-controlled vocabulary regarding the use of difficult airway wristbands in adults. Three researchers independently reviewed the full texts and selected the papers to be included based on the inclusion criteria.
    Our search generated 334 articles after removing duplicates. After reviewing full text articles, only seven studies were included. Here we found that most were from the United States, in which the authors report the use of in-patients\' wristbands in adults. According to the authors, the use of wristbands is being implemented as a measure of improved quality and safety of in-patients with difficult airway either known or suspected.
    The identification with wristbands of a difficult airway at an appropriate time is an identification strategy can have a low cost but a high impact on morbidity. It is pertinent to develop a methodology such as the use of wristbands, that allows a good classification and identification of patients with difficult airway in hospitals from Latin America.
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  • 文章类型: Journal Article
    2017年5月和12月,在长江(长江)的11条支流和三峡水库(TGR)的8个汇合带收集了永久淹没的沉积物样品(SS)。这项工作表明,王水消化是一个更简单的,与用氢氟酸(HF)完全消解相比,更可靠,更稳健的方法来测定沉积物中的痕量金属(TMs),以进行风险评估。我们的研究表明,在汇合处有大量的TM积累,并且有逐渐向该区域增加的趋势。铁和锰(氧)氢氧化物的存在与三峡大坝(TGD)产生的水动力条件及其运行被认为起着至关重要的作用。这项工作还发现,5月沉积物的[公式:见文字]浓度明显高于12月,这可能是由循环水动力条件和温暖的水引起的。沉积物中的TOC和TP都很低。尽管TN比安大略省环境部建议的最低影响水平高2倍,不确定它是否反映了自然背景水平或由于人为活动。通过比较使用不同的TM风险评估模型时获得的结论,进行了批判性讨论。在执行此练习时,强烈建议采取必要的预防措施。在这项研究中,未发现来自TMs或营养素的显著风险.
    Permanently submerged sediment samples (SS) were collected in the center stream of eleven tributaries of Changjiang (Yangtze River) and at eight confluence zones in the Three Gorges Reservoir (TGR) in May and December of 2017. The work showed that aqua regia digestion is a simpler, more reliable and robust method compared to total digestion with hydrofluoric acid (HF) for the determination of trace metals (TMs) in sediment for risk assessment purpose. Our study revealed a remarkable accumulation of TMs at the confluence zones and a trend of their gradual increase toward this zone. The presence of iron and manganese (oxy)hydroxides combined with hydrodynamic conditions created by the Three Gorges Dam (TGD) and its operation are believed to play a crucial role. This work also found that concentrations of [Formula: see text] in May sediment were significantly higher than those in December, which could have been caused by both the cyclic hydrodynamic conditions and the warmer water. TOC and TP were both very low in the sediment. Although TN was 2 times higher than the Lowest Effect Level suggested by the Ontario Ministry of Environment, it is uncertain if it reflects a natural background level or due to anthropogenic activities. A critical discussion is made by comparing the conclusions obtained when using different TMs risk assessment models. Necessary precautions are highly recommended when performing this exercise. In this study, no significant risk from either TMs or nutrients was identified.
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  • 文章类型: Journal Article
    In recent years, the impact of Plant Protection Products (PPPs) on insect pollinator decline has stimulated significant amounts of research, as well as political and public interest. PPP residues have been found in various bee-related matrices, resulting in governmental bodies worldwide releasing guidance documents on methods for the assessment of the overall risk of PPPs to different bee species. An essential part of these risk assessments are PPP residues found in pollen and nectar, as they represent a key route of exposure. However, PPP residue values in these matrices exhibit large variations and are not available for many PPPs and crop species combinations, which results in inaccurate estimations and uncertainties in risk evaluation. Additionally, residue studies on pollen and nectar are expensive and practically challenging. An extrapolation between different cropping scenarios and PPPs is not yet justified, as the behaviour of PPPs in pollen and nectar is poorly understood. Therefore, this review aims to contribute to a better knowledge and understanding of the fate of PPP residues in pollen and nectar and to outline knowledge gaps and future research needs. The literature suggests that four primary factors, the crop type, the application method, the physicochemical properties of a compound and the environmental conditions have the greatest influence on PPP residues in pollen and nectar. However, these factors consist of many sub-factors and initial effects may be disguised by different sampling methodologies, impeding their exact characterisation. Moreover, knowledge about these factors is ambiguous and restricted to a few compounds and plant species. We propose that future research should concentrate on identifying relationships and common features amongst various PPP applications and crops, as well as an overall quantification of the described parameters; in order to enable a reliable estimation of PPP residues in pollen, nectar and other bee matrices.
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  • 文章类型: Journal Article
    Background: Forensic psychiatric care treats mentally disordered offenders who suffer mainly from psychotic disorders, although comorbidities such as personality disorders, neurodevelopmental disorders, and substance abuse are common. A large proportion of these patients have committed violent crimes. Their care is involuntary, and their caregivers\' mission is complex: not only to rehabilitate the patient, but also to consider their risk for reoffending and their risk to society. The objective of this overview of systematic reviews is to identify, appraise, and summarize the existing knowledge in forensic psychiatric care and identify knowledge gaps that require further research. Methods: We undertook a systematic literature search for systematic reviews in five defined domains considered important in daily clinical practice within the forensic psychiatric care: (1) diagnostic assessment and risk assessments; (2) pharmacological treatment; (3) psychological interventions; (4) psychosocial interventions, rehabilitation, and habilitation; and (5) restraint interventions. The target population was mentally disordered offenders (forensic psychiatric patients aged >15 years). Each abstract and full text review was assessed by two of the authors. Relevant reviews then were assessed for bias, and those with moderate or low risk of bias were included. Results: Of 38 systematic reviews meeting the inclusion criteria, only four had a moderate risk of bias. Two aimed to incorporate as many aspects of forensic psychiatric care as possible, one investigated non-pharmacological interventions to reduce aggression in forensic psychiatric care, and one focused on women with intellectual disabilities in forensic care. However, most of the primary studies included in these reviews had high risks of bias, and therefore, no conclusions could be drawn. All of our identified domains must be considered knowledge gaps. Conclusion: We could not answer any of our research questions within the five domains because of the high risk of bias in the primary studies in the included systematic reviews. There is an urgent need for more research on forensic psychiatric care since all of our studied domains were considered knowledge gaps.
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  • 文章类型: Journal Article
    Patients with type II diabetes (T2DM) have an elevated risk for cardiovascular disease (CVD), and it is considered to be a leading cause of morbidity and premature mortality in these patients. Many traditional risk factors such as age, male sex, hypertension, dyslipidemia, glycemic control, diabetes duration, renal dysfunction, obesity, and smoking have been studied and identified as independent factors for CVD. Quantifying the risk of CVD among diabetics using the common risk factors in order to plan the treatment and preventive measures is important in the management of these patients as recommended by many clinical guidelines. Therefore, several risk assessment tools have been developed in different parts of the world for this purpose. These include the tools that have been developed for general populations and considered T2DM as a risk factor, and the tools that have been developed for T2DM populations specifically. However, due to the differences in sociodemographic factors and lifestyle patterns, as well as the differences in the distribution of various CVD risk factors in different diabetic populations, the external applicability of these tools on different populations is questionable. This review aims to address the applicability of the existing CVD risk models to the Omani diabetic population.
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