Retroperitoneal space

腹膜后间隙
  • 文章类型: Journal Article
    目的:腹膜后筋膜的复杂解剖结构决定了疾病在腹膜后的传播,目前尚不完全清楚。相互矛盾的报告导致放射学文献中的解剖学概念不足和不正确。
    方法:这篇综述将讨论放射学文献中普遍存在的先前概念,并将重点介绍它们的缺点。从最近的解剖学和胚胎学研究的新见解,连同成像示例,将用于阐明这些概念无法解释的腹膜后疾病传播模式。
    结果:融合筋膜和肾筋膜特别是产生平面和空间,充当腹膜后疾病传播的载体。其中一些平面和结构,比如肾筋膜的尾部延伸,以前没有在放射学文献中描述过。
    结论:新见解,包括各种筋膜,潜在的空间和平面,被纳入一个更新的组合腹膜后筋膜概念。
    OBJECTIVE: Spread of disease in the retroperitoneum is dictated by the complex anatomy of retroperitoneal fasciae and is still incompletely understood. Conflicting reports have led to insufficient and incorrect anatomical concepts in radiological literature.
    METHODS: This review will discuss previous concepts prevalent in radiological literature and their shortcomings will be highlighted. New insights from recent anatomical and embryological research, together with imaging examples, will be used to clarify patterns of disease spread in the retroperitoneum that remain unexplained by these concepts.
    RESULTS: The fusion fascia and the renal fascia in particular give rise to planes and spaces that act as vectors for spread of disease in the retroperitoneum. Some of these planes and structures, such as the caudal extension of the renal fascia, have previously not been described in radiological literature.
    CONCLUSIONS: New insights, including the various fasciae, potential spaces and planes, are incorporated into an updated combined retroperitoneal fascial concept.
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  • 文章类型: Case Reports
    背景:支气管源性囊肿是一种罕见的发育异常,属于先天性肠源性囊肿。它们来自肺芽,并在出生时存在。胚胎前肠是它们的起源。通常,它们位于胸腔内,特别是在胸腔的腔内纵隔或滞留在肺实质中,被认为是一种肺芽畸形。
    方法:一名49岁男性患者因体格检查中发现腹膜后肿块而入院。入院前两周,患者接受了体格检查和常规实验室检查,显示腹膜后区域有一个占位性肿块。患者未报告任何症状(如腹痛,胀气,恶心,呕吐,高烧,或发冷)。计算机断层扫描(CT)显示腹膜后占位性病变,增强最小,CT值为约36Hounsfield单位。病变未从胰体边界划定,与腹膜后局部密切相关。
    结论:经过一系列测试,确认了一个腹部肿块,提示实施腹腔镜腹膜后肿块切除术。在调查过程中,在胰腺的上后部区域发现了一个8cm×7cm的囊性圆形肿块,有明显的分界。随后,对肿块进行了完全切除.术后病理检查发现囊性肿块,其特征是内壁光滑。发现囊性肿块含有白色,其胶囊内的粘性液体。
    BACKGROUND: Bronchogenic cysts are rare developmental anomalies that belong to the category of congenital enterogenous cysts. They arise from lung buds and are present at birth. The embryonic foregut is their origin. Typically, they are located within the chest cavity, particularly in the cavum mediastinale of the thoracic cavity or lodged in the pulmonary parenchyma, and are considered a type of lung bud malformation.
    METHODS: A 49-year-old male patient was admitted to the hospital due to the detection of a retroperitoneal mass during a physical examination. Two weeks before admission, the patient underwent a physical examination and routine laboratory tests, which revealed a space-occupying mass in the retroperitoneal region. The patient did not report any symptoms (such as abdominal pain, flatulence, nausea, vomiting, high fever, or chills). The computed tomography (CT) revealed a retroperitoneal space-occupying lesion with minimal enhancement and a CT value of approximately 36 Hounsfield units. The lesion was not delineated from the boundary of the pancreatic body and was closely related to the retroperitoneum locally.
    CONCLUSIONS: Following a series of tests, an abdominal mass was identified, prompting the implementation of a laparoscopic retroperitoneal mass excision procedure. During the investigation, an 8 cm × 7 cm cystic round-shaped mass with a distinct demarcation was identified in the upper posterior region of the pancreas. Subsequently, full resection of the mass was performed. Postoperative pathological examination reveled a cystic mass characterized by a smooth inner wall. The cystic mass was found to contain a white, viscous liquid within its capsule.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Systematic Review
    背景:化疗和放疗被认为是II期精原细胞瘤患者的标准治疗方法;然而,这些疗法与长期毒性有关.最近,腹膜后淋巴结清扫术已成为一种替代策略,前三项II期试验于2023年发表,结果有希望.本研究进行了系统回顾和荟萃分析,以评估该手术作为IIA/B期精原细胞瘤患者的替代治疗方法。
    目的:精原细胞瘤是最常见的睾丸肿瘤,经常影响年轻的成年男性。II期精原细胞瘤的标准治疗包括化疗和放疗,但是这些疗法与长期毒性有关。因此,确定替代策略是至关重要的。在这里,我们进行了系统评价和荟萃分析,以评估腹膜后淋巴结清扫术(RPLND)治疗该疾病的有效性和安全性.
    方法:我们系统地搜索了PubMed,Embase,和Cochrane数据库,用于评估RPLND作为IIA/B期精原细胞瘤的主要治疗方法。使用随机效应模型,我们计算了单一比例和均值,以及合并的2年无复发生存率,风险率和95%CI.
    结果:纳入了7项研究,包括331名男性患有II期精原细胞瘤。在汇总分析中,复发率为17.69%(95%CI12.31-24.75),2年RFS率为81%(95%CI0.77-0.86)。并发症发生率为9.16%(95%CI6.16~13.42),Clavien-Dindo>2并发症发生率为8.83%(95%CI5.76-13.31),逆行射精率为7.01%(95%CI3.54~13.40)。中位手术时间为174.68分钟(95%CI122.17-249.76分钟),中位失血量为105.91mL(95%CI46.89-239.22mL),无淋巴结受累证据的患者为0-16%。
    结论:用于治疗IIA/B期精原细胞瘤的原发性RPLND具有良好的RFS率,并发症和复发率低。这些发现提供了证据,表明该手术是这些患者的可行替代疗法。
    BACKGROUND: Chemotherapy and radiation therapy are considered standard treatments for stage II seminoma patients; however, these therapies are associated with long-term toxicities. Recently, retroperitoneal lymph node dissection has emerged as an alternative strategy, and the first three phase II trials were published in 2023 with promising results. The present study conducted a systematic review and meta-analysis to evaluate this surgery as an alternative treatment for stage IIA/B seminoma patients.
    OBJECTIVE: Seminomas are the most common testicular tumors, often affecting young adult males. Standard treatments for stage II seminomas include chemotherapy and radiation therapy, but these therapies are associated with long-term toxicities. Thus, identifying alternative strategies is paramount. Herein, we conducted a systematic review and meta-analysis to appraise the efficacy and safety of retroperitoneal lymph node dissection (RPLND) for treating this condition.
    METHODS: We systematically searched the PubMed, Embase, and Cochrane databases for studies evaluating RPLND as a primary treatment for stage II A/B seminomas. Using a random-effects model, single proportion and means and pooled 2-year recurrence-free survival rates with hazard rates and 95% CI were calculated.
    RESULTS: Seven studies were included, comprising 331 males with stage II seminomas. In the pooled analysis, the recurrence rate was 17.69% (95% CI 12.31-24.75), and the 2-year RFS rate was 81% (95% CI 0.77-0.86). The complication rate was 9.16% (95% CI 6.16-13.42), the Clavien-Dindo > 2 complication rate was 8.83% (95% CI 5.76-13.31), and the retrograde ejaculation rate was 7.01% (95% CI 3.54-13.40). The median operative time was 174.68 min (95% CI 122.17-249.76 min), median blood loss was 105.91 mL (95% CI 46.89-239.22 mL), and patients with no evidence of lymph node involvement ranged from 0-16%.
    CONCLUSIONS: Primary RPLNDs for treating stage IIA/B seminomas have favorable RFS rates, with low complication and recurrence rates. These findings provide evidence that this surgery is a viable alternative therapy for these patients.
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  • 文章类型: Review
    背景:腹膜后分化脂肪肉瘤(RPDDL)是一种罕见的恶性肿瘤,由于在腹膜后腔中具有足够的空间并且在疾病的早期阶段缺乏临床表现,因此通常多年未被发现。外科手术通常作为治疗的首选。然而,手术后容易局部复发,导致不良预后。我们的目的是从新病例中吸取有益的教训,为疾病的管理提供一些经验。
    方法:我们描述了一名55岁的男性患者,他因3周的左腰持续隐痛而入院。在体格检查中触诊了左上腹部的大肿块。此外,影像学检查显示肿块直径约21厘米,一些邻近的重要器官被侵入,这给完成手术切除带来了很大的挑战。
    方法:术后病理证实肿块为RPDDL,浸润胰腺等周围重要结构,脾,脾左肾上腺,左肾,和有肿瘤栓子的脉管系统。
    方法:我们的多学科团队进行了肿块的手术切除。患者术后1个月接受化疗。
    结果:化疗的效果似乎不令人满意。手术后约2个月考虑肿瘤的局部多灶性复发。最后,他放弃了任何治疗,死于这种疾病。
    结论:定期体检和超声筛查可以尽早发现疾病,特别是对于60-70岁的高危人群,应该推广。不完全切除,血管浸润,中断术后治疗可能导致不良预后。因此,我们认为这种疾病的患者可能受益于完整的手术切除和不间断的辅助治疗.
    BACKGROUND: Retroperitoneal dedifferentiated liposarcoma (RPDDL) is an uncommon malignancy, which often remains undetected for many years due to having adequate space in the retroperitoneal cavity and lacking clinical manifestations in the early stage of the disease. Surgical procedure is usually used as the first choice for treatment. However, it is prone to local recurrence after the operation, resulting in an unfavorable prognosis. Our aim is to draw useful lessons from the new case and provide some experience for management of the disease.
    METHODS: We describe a 55-year-old male patient who was admitted for a 3-week history of persistent dull ache of the left waist. A large mass of the left upper abdomen was palpated in physical examination. Moreover, the imaging examination revealed that the diameter of the mass was about 21 cm, and some adjacent vital organs were invaded, which brought great challenges to complete surgical resection.
    METHODS: The postoperative pathological results confirmed that the mass was RPDDL with invasion of the surrounding vital structures including pancreas, spleen, left adrenal gland, left kidney, and vasculature with tumor emboli.
    METHODS: Surgical resection of the mass was performed by our multidisciplinary team. The patient received chemotherapy 1 month after surgery.
    RESULTS: The effect of chemotherapy seemed to be unsatisfactory. Local multifocal recurrence of the tumor was considered about 2 months after surgery. Finally, he gave up any treatments and died of the disease.
    CONCLUSIONS: Regular physical examination and ultrasound screening may detect the disease as early as possible, especially for high-risk group aged 60 to 70, which should be popularized. Incomplete resection, vascular invasion, and interruption of postoperative treatment may lead to an unfavorable prognosis. Therefore, we think that patients with the disease may benefit from complete surgical resection and uninterrupted adjuvant therapy.
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  • 文章类型: Review
    背景:怀孕期间腹膜后良性囊肿极为罕见,并且通常在达到非常大的尺寸之前一直无症状。诊断通常依赖于病理组织活检。进行1步或2步手术治疗的决定应针对每个病例而不是一概而论。
    方法:本病例报告介绍了一名孕妇的独特情况,该孕妇证实妊娠并伴有大的腹膜后囊肿。该患者在初次怀孕期间患有腹膜后囊肿,在第一次剖腹产时未被发现。然而,这是在她第二次怀孕时发现的,当时它已经长到13.0厘米×15.0厘米×25.0厘米,并从肝脏边缘延伸到右卵巢盆腔盆底漏斗韧带。因此,在她第二次剖腹产时顺利切除。
    方法:术后病理提示:巨大的腹膜后黏液性囊腺瘤。
    方法:再次剖宫产术中顺利切除巨大腹膜后囊肿,进行1步手术治疗。
    结果:在腰硬联合麻醉下,一名活女婴在383/7孕周分娩,新生儿体重为3200g。在气管插管全身麻醉下,腹膜后巨大囊肿顺利切除,无并发症。
    结论:本病例报告的发现有助于理解诊断模式,与妊娠相关的巨大腹膜后囊肿的手术方法和术后考虑。
    BACKGROUND: Retroperitoneal benign cysts during pregnancy are extremely rare and often remain asymptomatic until they attain a very large size. Diagnosis typically relies on a pathological tissue biopsy. The decision to pursue 1-step or 2-step surgical treatment should be tailored to each individual case rather than generalized.
    METHODS: This case report presents the unique scenario of a pregnant woman with a confirmed pregnancy complicated by a large retroperitoneal cyst. The patient had a retroperitoneal cyst during her initial pregnancy, which went undetected during the first cesarean section. However, it was identified during her second pregnancy by which time it had grown to 13.0 cm × 15.0 cm × 25.0 cm, and extended from the liver margin to right ovarian pelvic infundibulopelvic ligament. Consequently, it was removed smoothly during her second cesarean section.
    METHODS: Postoperative pathology results indicated a massive retroperitoneal mucinous cystadenoma.
    METHODS: The giant retroperitoneal cyst was smoothly excised during the second cesarean delivery for 1-step surgical treatment.
    RESULTS: Under the combined spinal and epidural anesthesia, a live female infant was delivered at 38 3/7 gestational weeks and the neonatal weight was 3200g. Under general anesthesia with endotracheal intubation, the giant retroperitoneal cyst was excised smoothly without complications.
    CONCLUSIONS: The findings of this case report contribute to the understanding of the diagnostic modalities, surgical approaches and postoperative considerations of giant retroperitoneal cysts associated with pregnancy.
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  • 文章类型: Meta-Analysis
    评价原发性腹膜后淋巴结清扫术(RPLND)治疗临床期(CS)II型精原细胞睾丸生殖细胞瘤(TGCT)的疗效和安全性。使用PubMed进行文献检索,Scopus,和Cochrane图书馆于2023年7月进行,以根据系统评价和荟萃分析(PRISMA)指南的首选报告项目确定相关研究。使用随机效应模型计算合并复发率和治疗相关并发症。在1997年至2023年之间发表的总共8项研究,包括355名患者被选择进行系统评价和荟萃分析,总体中位随访时间为38个月。总体复发率和内部复发率分别为0.14(95%CI:0.08-0.22)和0.04(95%CI:0.00-0.11),分别。≥ClavienDindoIII级并发症的总合并率为0.04(95%CI:0.01-0.10);没有明显的异质性(I^2=35.10%,P=0.19)。顺行射精保留,总体合并率为0.98(95%CI:0.95-1.00);卡方和I2检验无明显异质性(I^2=0.00%,P=0.58)。原发性RPLND是CSII型精原细胞瘤TGCT患者的一种安全有效的治疗选择,具有非常有希望的治愈率和较低的治疗相关不良事件。中期随访。然而,由于缺乏对当前护理标准的比较研究和有限的随访,个体决策必须由知情患者与多学科团队在共同决策过程中共同做出.
    To evaluate the oncological outcomes and safety of primary retroperitoneal lymph node dissection (RPLND) in patients with clinical stage (CS) II seminomatous testicular germ cell tumor (TGCT). A literature search using PubMed, Scopus, and Cochrane Library was conducted on July 2023 to identify relevant studies according to the Preferred Reporting Items for Systematic Review and Meta Analysis (PRISMA) guidelines. The pooled recurrence rate and treatment-related complications were calculated using a random effects model. Overall 8 studies published between 1997 and 2023 including a total of 355 patients were selected for systematic review and meta-analysis with the overall median follow-up of 38 months. The overall and infield recurrence rate were 0.14 (95% CI: 0.08-0.22) and 0.04 (95% CI: 0.00-0.11), respectively. The overall pooled rate of ≥ Clavien Dindo grade III complications was 0.04 (95% CI: 0.01-0.10); there was no significant heterogeneity (I^2 = 35.10%, P = 0.19). Antegrade ejaculation was preserved with the overall pooled rate of 0.98 (95% CI: 0.95-1.00); there was no significant heterogeneity on Chi-square and I2 tests (I^2 = 0.00%, P = 0.58). Primary RPLND is a safe and effective treatment option for patients with CS II seminomatous TGCT resulting highly promising cure rates combined with low treatment-associated adverse events, at medium-term follow-up. However, owing to the lack of comparative studies to the current standard of care and the limited follow-up, individual decision must be made with the informed patient in a shared decision process together with a multidisciplinary team.
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  • 文章类型: Review
    Femoral nerve damage, especially in proximal retroperitoneal space, is rare. Therefore, surgical strategy is still unclear for these patients. Various specialists discuss repair with autografts or neurotization by the obturator nerve or its muscular branch.
    OBJECTIVE: To demonstrate the diagnostic algorithm for proximal femoral nerve injury and favorable outcomes after repair with long autografts.
    METHODS: We assessed movements and sensitivity using a five-point scale, as well as ultrasound, magnetic resonance imaging and electroneuromyography data in a patient with extended iatrogenic femoral nerve damage before and after repair with long autografts (10.5 cm).
    CONCLUSIONS: The patient had complete femoral nerve interruption in proximal retroperitoneal space with 10-cm defect that required repair with five autografts from two sural nerves. Postoperative ultrasound and magnetic resonance imaging revealed signs of graft survival and no neuroma within the nerve suture lines. The first signs of motor recovery occurred after 10 months. After 14 months, strength of quadriceps femoris muscle comprised 4 points, and electroneuromyography confirmed re-innervation.
    CONCLUSIONS: Femoral nerve repair with autografts for complete proximal anatomical interruption can provide sufficient restoration of movements and sensitivity. Therefore, this surgical option should be preferred instead of neurotization. Ultrasound, MRI and ENMG are valuable to clarify the diagnosis and state of the autografts.
    В связи с редкостью повреждений бедренного нерва с большим его дефектом, особенно в его проксимальном забрюшинном пространстве, вариант операции в данных случаях не определен — обсуждается вопрос об аутопластике, невротизации запирательным нервом или его мышечной ветвью.
    UNASSIGNED: Продемонстрировать алгоритм диагностики при повреждении бедренного нерва в его проксимальном забрюшинном пространстве и возможность благоприятного исхода при аутопластике трансплантатами большой длины.
    UNASSIGNED: Работа основана на оценке движений и чувствительности в зоне бедренного нерва по 5-балльной шкале, данных ультразвукового исследования (УЗИ), магнитно-резонансной томографии (МРТ) и электронейромиографии (ЭНМГ) у пациентки с его ятрогенным повреждением, до и после аутопластики большого дефекта нервного ствола трансплантатами большой длины (10,5 см).
    UNASSIGNED: В приведенном клиническом случае у пациентки был выявлен полный перерыв бедренного нерва в его проксимальном забрюшинном пространстве с дефектом в 10 см, что потребовало аутопластики пятью трансплантатами, сформированными из двух икроножных нервов. После операции при динамическом УЗИ и МРТ были определены признаки «выживания» трансплантатов и отсутствие невромы на линиях шва нерва. Через 10 мес были обнаружены первые признаки восстановления движений, а на 14-м месяце сила четырехглавой мышцы бедра была оценена в 4 балла, ЭНМГ подтвердила ее реиннервацию.
    UNASSIGNED: Аутопластика бедренного нерва при полном анатомическом перерыве в его проксимальном забрюшинном пространстве трансплантатами большой длины может обеспечить клинически достаточную степень восстановления движений и чувствительности, в связи с чем этому варианту оперативного лечения следует отдавать предпочтение перед операцией невротизации. Уточнить диагноз, состояние имплантированных аутотрансплантатов помогают УЗИ, МРТ и ЭНМГ.
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  • 文章类型: Case Reports
    背景:左侧前腹膜后入路是治疗腰骶部脊柱疾病的首选方法,因为血管损伤的风险降低。脊柱两侧存在多种罕见的静脉变异,像双侧下腔静脉复制(DIVC),可能会使这个地区的手术复杂化。目前的研究描述了两个罕见的双侧重复下腔静脉与髂内和性腺静脉相关的病例。
    方法:在常规人体解剖89例(男性45例,44名女性)个体。课程,检查并记录每个重复下腔静脉的关系和形态。
    结果:89人中有2人(2.2%)(1名男性,1名女性)解剖的个体显示下腔静脉的双侧重复肾下段。在这两种情况下,主动脉前干(静脉)最大,左下腔静脉最小。两例双侧DIVC均表现为异常的髂内交通静脉,髂内静脉,和左性腺静脉的引流部位。
    结论:重复的下腔静脉可能存在相关的静脉异常,如与性腺和髂内静脉相关的静脉异常。了解重复的下腔静脉及其相关的静脉异常对于准确识别和诊断血管功能障碍以及改善多种外科专业的放射学解释至关重要。
    BACKGROUND: The left side anterior retroperitoneal approach is preferred for the management of lumbosacral spine disorders as there is reduced risk for vascular injury. The presence of multiple and uncommon venous variations on either side of the spine, like the bilateral duplicated inferior vena cava (DIVC), may complicate surgery in this region. The current study describes two rare cases of bilateral duplicated inferior vena cava associated with internal iliac and gonadal veins.
    METHODS: The cases were identified during routine human dissections of the posterior abdominal wall of 89 (45 males, 44 females) individuals. The course, relations and morphometry of each duplicated inferior vena cava were examined and recorded.
    RESULTS: Two (2.2%) of the 89 (1 male, 1 female) dissected individuals showed the presence of bilateral duplicated infrarenal segments of the inferior vena cava. In both cases, the pre-aortic trunk (vein) was the largest and the left inferior vena cava was the smallest. Both cases of bilateral DIVC presented with anomalous interiliac communicating veins, internal iliac veins, and drainage sites of the left gonadal veins.
    CONCLUSIONS: The duplicated inferior vena cava may present with associated venous anomalies like those related to the gonadal and internal iliac veins. Knowledge of the duplicated inferior vena cava and its associated venous anomalies may be essential for accurately identifying and diagnosing vascular dysfunction and improving radiological interpretation across multiple surgical specialities.
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  • 文章类型: Review
    肾脓是一种严重的疾病,可以导致肾功能障碍,器官的丧失,甚至由于其并发症而致命的结局。潜在的病因包括结石,复发性尿路感染,输尿管狭窄,肾盂输尿管连接部梗阻,恶性肿瘤,和腹膜后纤维化.脓肾的罕见并发症之一是腹膜后破裂,与腹部自发连通,导致继发性腹膜炎。我们提出了这样一个案例,这是关于腹腔内腹膜破裂部位的第一个视频记录报告。
    Pyonephrosis is a serious condition that can lead to kidney dysfunction, loss of the organ, and even fatal end due to its complications. The underlying etiologic factors include lithiasis, recurrent urinary infections, ureter stricture, ureteropelvic junction obstruction, malignancy, and retroperitoneal fibrosis. One of the rare possible complications of pyonephrosis is a retroperitoneal rupture with spontaneous communication to the abdomen causing secondary peritonitis. We present such a case which is the first video-documented report of the peritoneal rupture site within the abdominal cavity.
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