Stephanoascusciferrii,自然界中普遍存在的条件致病真菌,在免疫力低下的患者中更常见。然而,文献很少报道在腹膜透析患者中由Stephanoascusciferrii引起的感染。这里,我们详细介绍了一例66岁的肾衰竭女性在腹膜透析期间发生导管相关性感染的病例.透析液浊度促使通过微生物培养物检测腹膜透析液和试管中的Stephanocciferrii。随后的治疗涉及抗真菌药物和过渡到血液透析,导致腹膜炎症状消失,患者出院。近年来,真菌感染,尤其是透析相关的感染,正在上升。这标志着首例由Stephanoascusciferrii引起的导管相关性腹膜炎感染。与细菌感染相比,由于药物选择有限,真菌感染构成了挑战,显著的副作用,和延长治疗持续时间。因此,及时的病原体诊断和药物敏感性测试对于有效的临床治疗至关重要。实质上,这份科学病例报告强调了在一名患有肾衰竭的腹膜透析患者中,罕见的导管相关性腹膜炎的发生率,强调独特的管理挑战,并强调在这种情况下及时诊断和适当干预的关键意义。
Stephanoascus ciferrii, a conditional pathogenic fungus prevalent in nature, is more frequently encountered in patients with compromised immunity. However, the literature rarely
reports infections caused by Stephanoascus ciferrii in peritoneal dialysis patients. Here, we detail the
case of a 66-year-old female suffering from renal failure who experienced catheter-related infection during peritoneal dialysis. Dialysate turbidity prompted the detection of Stephanoascus ciferrii in both peritoneal dialysate and tubes through microbiological cultures. Subsequent treatment involved antifungal drugs and a transition to hemodialysis, resulting in the disappearance of peritonitis symptoms and the patient\'s discharge. In recent years, fungal infections, particularly dialysis-related infections, are on the rise. This marks the first reported
case of catheter-related peritonitis infection caused by Stephanoascus ciferrii. Compared to bacterial infections, fungal infections pose challenges due to limited drug options, significant side effects, and prolonged treatment durations. Hence, prompt pathogen diagnosis and drug sensitivity testing are crucial for effective clinical treatment. In essence, this scientific
case report underscores the uncommon occurrence of catheter-related peritonitis attributed to Stephanoascus ciferrii in a peritoneal dialysis patient with renal failure, emphasizing the distinctive management challenges and underscoring the critical significance of prompt diagnosis and suitable intervention in such instances.