当大多数真核细胞经历活化或凋亡时,膜微粒从这些细胞的质膜脱落。并释放到细胞外环境中。它们的组成取决于细胞起源和触发它们形成的过程。一些证据表明,膜微粒可能能够促进细胞间的交叉对话,并在调节存活中起重要作用。扩散,分化,造血细胞的粘附和趋化性。这里,组件,综述了膜微粒的形成机制及其在造血中的调控作用。
Membrane microparticles are shed from the plasma membrane of most eukaryotic cells when these cells were undergone activation or apoptosis, and released into the extracellular environment. Their composition depends on the cellular origin and processes triggering their formation. Several lines of evidence suggest that membrane microparticles might be able to facilitate cell-cell cross-talk and play an important roles in the regulation of survival, proliferation, differentiation, adhesion and chemotaxis of hematopoietic cells. Here, the components, mechanism of formation and the regulatory roles of membrane microparticles in hematopoiesis were reviewed.