■我们的研究旨在评估老年人膝骨关节炎(KOA)患者股四头肌肌肉参数的差异。
■该研究包括KOA组(KG)中40例诊断为单侧膝骨关节炎的患者和对照组(CG)中40例无症状的老年人。肌肉超声平均回波强度和剪切模量,以及股直肌(RF)的音调和刚度,中肌(VM),和股外侧肌(VL)进行分析。此外,进行了临床相关性。
■在KG组中,回波强度有显著差异,剪切模量,以及受影响侧和不受影响侧之间的射频音调(p=0.003,0.019,0.014),而VM在剪切模量和色调方面表现出显著差异(p=0.006,0.002)。此外,VL在回波强度方面表现出显著差异,剪切模量,和刚度(p=0.007,0.006,0.010)。与CG组相比,KG组患者患侧射频回波强度存在显著差异(p=0.001).VM在回波强度和剪切模量方面表现出统计学上的显着差异(p<0.001,p=0.008),而VL在回波强度方面表现出统计学上的显著差异,tone,和刚度(p<0.001,p=0.028,p<0.001)。相关性结果显示,单侧KOA患者,VM,VL回波强度与K-L分级相关(r=0.443,p=0.004;r=0.469,p=0.002)。VL的音调与VAS和WOMAC相关(r=0.327,p=0.039;r=0.344,p=0.030)。
■在单侧KOA患者中,股四头肌的参数在受影响侧和未受影响侧之间表现出不对称,以及健康老年人的优势侧和KOA的受影响侧之间的差异。
UNASSIGNED: Our study aims to evaluate differences in muscle parameters of the quadriceps muscles in patients with knee osteoarthritis (KOA) in older adults.
UNASSIGNED: The study included 40 patients diagnosed with unilateral knee osteoarthritis in the KOA group (KG) and 40 asymptomatic elderly individuals in the control group (CG). Muscle ultrasonic mean echo intensity and shear modulus, as well as tone and stiffness of the rectus femoris (RF), vastus medialis (VM), and vastus lateralis (VL) were analyzed. Additionally, clinical correlations were performed.
UNASSIGNED: In the KG group, there were significant differences in echo intensity, shear modulus, and tone between the affected and unaffected sides for RF (p=0.003, 0.019, 0.014), while VM showed significant differences in shear modulus and tone (p=0.006, 0.002). Additionally, VL exhibited significant differences in echo intensity, shear modulus, and stiffness (p=0.007, 0.006, 0.010). Compared to the CG group, the KG group showed significant differences in echo intensity of the affected side RF (p=0.001). VM exhibited statistically significant differences in echo intensity and shear modulus (p < 0.001, p=0.008), while VL showed statistically significant differences in echo intensity, tone, and stiffness (p < 0.001, p=0.028, p < 0.001). The correlation results showed that patients with unilateral KOA, VM, and VL echo intensity were correlated with K-L grade (r = 0.443, p=0.004; r = 0.469, p=0.002). The tone of VL was correlated with VAS and WOMAC (r = 0.327, p=0.039; r = 0.344, p=0.030).
UNASSIGNED: The parameters of the quadriceps femoris muscle exhibit asymmetry between the affected and unaffected sides in patients with unilateral KOA, as well as a difference between the dominant side of healthy older individuals and the affected side of KOA.