背景:加拿大武装部队中超过85%的活跃成员已暴露于与创伤后应激障碍(PTSD)发展有关的潜在创伤事件。在向平民生活过渡的时候,八分之一的退伍军人可能被诊断为PTSD。鉴于PTSD在军人和退伍军人人群中的高患病率,考虑到他们独特的挑战和经验,提供有效的治疗对于这些人群的心理健康支持和福祉至关重要。
目的:本文提出了一项荟萃分析和系统评价方案,该方案将研究军事相关PTSD的治疗方法的有效性。
方法:本PROSPERO预注册的荟萃分析是根据PRISMA(系统评价和荟萃分析的首选报告项目)和Cochrane指南进行的。使用PsycInfo数据库对文献进行了全面搜索,Medline,Embase,CINAHL,和ProQuest论文和论文。使用验证的PTSD量表,将根据研究中PTSD症状评分随时间的变化来计算效果大小。多层次荟萃分析将检查总体效果,研究之间的影响,以及军事人群PTSD治疗的现有证据的研究内效果。效果大小将在药物治疗之间进行比较,心理治疗,和替代/新兴治疗干预措施。最后,荟萃回归和亚组分析将探讨临床特征的调节作用(例如,创伤后应激障碍症状群),治疗方法(例如,心理治疗和替代疗法的治疗方向以及药物治疗中的药物分类),以及治疗特征(例如,干预时间)对治疗结果的影响。
结果:文献检索于2021年4月14日完成。删除副本后,共筛选了12,002项研究纳入.截至2021年7月,标题和摘要筛选已经完成,纳入12,002项研究中的1469项(12.23%)用于全文审查。全面审查预计将于2021年夏季完成,初步结果预计将于2021年初冬公布。
结论:本荟萃分析将提供有关军事相关PTSD的各种治疗方法的疗效和有效性的证据的当前状态的信息,并确定可能影响治疗结果的因素。结果将为服务提供商和服务用户提供临床决策。最后,研究结果将为未来的治疗发展和实践建议提供见解,以更好地支持军人和退伍军人人群的福祉。
背景:PROSPEROCRD42021245754;https://tinyurl.com/y9u57c59.
■DERR1-10.2196/33151。
BACKGROUND: Over 85% of active members of the Canadian Armed Forces have been exposed to potentially traumatic events linked to the development of
posttraumatic stress disorder (PTSD). At the time of transition to civilian life, as high as 1 in 8 veterans may be diagnosed with PTSD. Given the high prevalence of PTSD in military and veteran populations, the provision of effective treatment considering their unique challenges and experiences is critical for mental health support and the well-being of these populations.
OBJECTIVE: This paper presents the protocol for a meta-analysis and systematic
review that will examine the effectiveness of treatment approaches for military-related PTSD.
METHODS: This PROSPERO-preregistered meta-analysis is being conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and Cochrane guidelines. A comprehensive search of the literature was conducted using the databases PsycInfo, Medline, Embase, CINAHL, and ProQuest Dissertation & Theses. Effect sizes will be computed based on changes in PTSD symptom scores over time across studies using validated PTSD scales. A multilevel meta-analysis will examine the overall effects, between-study effects, and within-study effects of available evidence for PTSD treatments in military populations. Effect sizes will be compared between pharmacotherapeutic, psychotherapeutic, and alternative/emerging treatment interventions. Finally, meta-regression and subgroup analyses will explore the moderating roles of clinical characteristics (eg, PTSD symptom clusters), treatment approaches (eg, therapeutic orientations in psychotherapy and alternative therapies and classifications of drugs in pharmacotherapy), as well as treatment characteristics (eg, length of intervention) on treatment outcomes.
RESULTS: The literature search was completed on April 14, 2021. After the removal of duplicates, a total of 12,002 studies were screened for inclusion. As of July 2021, title and abstract screening has been completed, with 1469 out of 12,002 (12.23%) studies included for full-text
review. Full
review is expected to be completed in the summer of 2021, with initial results expected for publication by early winter of 2021.
CONCLUSIONS: This meta-analysis will provide information on the current state of evidence on the efficacy and effectiveness of various treatment approaches for military-related PTSD and identify factors that may influence treatment outcomes. The results will inform clinical decision-making for service providers and service users. Finally, the findings will provide insights into future treatment development and practice recommendations to better support the well-being of military and veteran populations.
BACKGROUND: PROSPERO CRD42021245754; https://tinyurl.com/y9u57c59.
UNASSIGNED: DERR1-10.2196/33151.