■脾EB病毒(EBV)阳性的炎性滤泡树突状细胞肉瘤(FDCS)很少见,影像学征象尚不清楚。COVID-19已被证实是肺炎的病因,可引起包括心肌炎在内的多种疾病。然而,尚未报道它是EBV阳性炎性FDCS加重或激活的原因.
■目的是提取脾脏中EBV阳性炎性FDCS的影像学特征,并分析该病例特殊特征的原因。
■通过分析患者的治疗过程和影像学检查(一名77岁女性因全身不适和疼痛症状入院。一年前,当她因COVID-19肺炎入院时,胸部CT扫描显示她患有脾肿瘤。在这次录取期间,CT扫描显示脾脏内有两个不规则形状和不均匀致密的软组织密度肿块,在固体组件内和沿边缘的对比度增强的调整上不均匀增强。PET/CT扫描显示肿块中葡萄糖代谢升高。术后病理诊断为脾EBV阳性炎性FDCS。),阅读文献,梳理疾病的认知过程,流行病学,EBV阳性炎性FDCS的病理资料,我们讨论了该疾病的影像学表现和可能的鉴别诊断。
■患者最终被诊断为脾EBV阳性炎性FDCS。
■脾脏中EBV阳性炎性FDCS的影像学特征包括出血和坏死的高发生率,固体部分的持续适度增强,肿瘤边缘的“囊状增强”结构,以及可能具有高标准化摄取值(SUV)的活跃葡萄糖代谢。COVID-19感染和长期的COVID-19后遗症可能会加剧和激活脾脏中EBV阳性的炎性FDCS,机制有待进一步研究。
UNASSIGNED: Spleen Epstein-Barr Virus (EBV)-positive inflammatory follicular dendritic cell sarcoma (FDCS) is rare, and the imaging signs are unclear. The COVID-19 has been confirmed to be the cause of pneumonia and can cause a variety of diseases including myocarditis. However, it has not been reported to be the cause of the exacerbation or activation of EBV-positive inflammatory FDCS.
UNASSIGNED: The objective is to extract the imaging features of EBV-positive inflammatory FDCS in the spleen and analyze the reasons for the special features of this
case.
UNASSIGNED: By analyzing the patient\'s treatment process and imaging examinations (A 77-year-old female was admitted to the hospital due to generalized discomfort and pain symptoms. When she was admitted to the hospital a year earlier with COVID-19 pneumonia, a chest CT scan showed that she had a splenic tumor. During this admission, CT scans showed two irregularly shaped and unevenly dense soft tissue density masses within the spleen, with uneven enhancement on contrast-enhanced im-aging within the solid components and along the edges. PET/CT scans revealed elevated glucose metabolism in the masses. Postoperative pathological diagnosis confirmed splenic EBV-positive inflammatory FDCS.), reading the literature, sorting out the disease cognitive process, epidemiology, and pathological data of EBV-positive inflammatory FDCS, we discussed the imaging manifestations and possible differential diagnosis of the disease.
UNASSIGNED: The patient was finally diagnosed with splenic EBV-positive inflammatory FDCS.
UNASSIGNED: Imaging features of EBV-positive inflammatory FDCS in the spleen include a high incidence of hemorrhage and necrosis, persistent moderate enhancement of the solid portion, a \"capsular-like enhancement\" structure at the tumor edge, and possibly active glucose metabolism with high Standardized Uptake Values (SUVs). COVID-19 infection and long-term COVID-19 sequelae may exacerbate and activate EBV-positive inflammatory FDCS in the spleen, and the mechanism remains to be further studied.