Physical examination

体格检查
  • 文章类型: Journal Article
    文献中先前提出的评估肩袖相关肩痛患者的方法,基于特殊的骨科测试来精确识别导致肩部症状的结构最近受到了挑战。这开启了另一种体检方式的可能性。
    要分析肩部活动范围的差异,肩袖相关肩痛患者与无症状组之间的力量和胸椎后凸。
    本研究的方案已在国际前瞻性系统评价登记册(PROSPERO)(注册号CRD42021258924)中注册。在MEDLINE中进行了观察性研究的数据库搜索,EMBASE,WOS和CINHAL至2023年7月,与无症状组相比,评估肩部或颈部神经肌肉骨骼非侵入性体检。两名研究人员评估了资格和研究质量。采用纽卡斯尔渥太华量表评价方法学质量。
    选择8项研究(N=604)进行定量分析。荟萃分析显示,肩关节屈曲的影响较大(I2=91.7%,p<0.01,HG=-1.30),外旋转(I2=83.2%,p<0.01,HG=-1.16)和内部旋转运动范围(I2=0%,p<0.01,HG=-1.32)。关于肩部力量;只有内旋强度显示出统计学差异,影响很小(I2=42.8%,p<0.05,HG=-0.3)。
    有中度到有力的证据表明肩袖相关的肩痛患者肩关节屈曲较少,内部和外部旋转的运动范围和小于无症状个体的内部旋转强度。
    UNASSIGNED: The methods previously proposed in the literature to assess patients with rotator cuff related shoulder pain, based on special orthopedic tests to precisely identify the structure causing the shoulder symptoms have been recently challenged. This opens the possibility of a different way of physical examination.
    UNASSIGNED: To analyze the differences in shoulder range of motion, strength and thoracic kyphosis between rotator cuff related shoulder pain patients and an asymptomatic group.
    UNASSIGNED: The protocol of the present research was registered in the International Prospective Register of Systematic Review (PROSPERO) (registration number CRD42021258924). Database search of observational studies was conducted in MEDLINE, EMBASE, WOS and CINHAL until July 2023, which assessed shoulder or neck neuro-musculoskeletal non-invasive physical examination compared to an asymptomatic group. Two investigators assessed eligibility and study quality. The Newcastle Ottawa Scale was used to evaluate the methodology quality.
    UNASSIGNED: Eight studies (N = 604) were selected for the quantitative analysis. Meta-analysis showed statistical differences with large effect for shoulder flexion (I2 = 91.7%, p < 0.01, HG = -1.30), external rotation (I2 = 83.2%, p < 0.01, HG = -1.16) and internal rotation range of motion (I2 = 0%, p < 0.01, HG = -1.32). Regarding to shoulder strength; only internal rotation strength showed statistical differences with small effect (I2 = 42.8%, p < 0.05, HG = -0.3).
    UNASSIGNED: There is moderate to strong evidence that patients with rotator cuff related shoulder pain present less shoulder flexion, internal and external rotation range of motion and less internal rotation strength than asymptomatic individuals.
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  • 文章类型: Journal Article
    一氧化二氮在医学上用作麻醉剂;在食品工业中用作调味品的推进剂;并因其欣快感和解离作用而消遣。我们报告了三例一氧化二氮误用导致严重的,有症状的钴胺素(维生素B12)缺乏,其中一氧化二氮的迹象本身使用,以及毒性的迹象,被观察到,包括掌骨头上的特征性掌骨老茧,还有冻伤.这些体征可能有助于临床医生识别一氧化二氮的使用并及时诊断一氧化二氮的毒性。
    Nitrous oxide is used medically as an anesthetic agent; in the food industry as a propellant for condiments; and recreationally for its euphoric and dissociative effects. We report three cases of nitrous oxide misuse causing severe, symptomatic cobalamin (vitamin B12) deficiency in which signs of nitrous oxide use per se, as well as signs of toxicity, were observed, including characteristic palmar calluses over the metacarpal heads, and frostbite. These signs may assist clinicians in the recognition of nitrous oxide use and the timely diagnosis of nitrous oxide toxicity.
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  • 文章类型: Journal Article
    背景:所有新生儿都要接受新生儿的全面检查和筛查(CESoN),以验证新生儿的总体健康和福祉,并筛查疾病和重大先天性疾病的体征和症状。通常在出生后72小时内。为了健康,足月妊娠新生儿,这种检查通常由合格的保健医生进行,助产士,刚从产妇服务机构出院前的护士或医生。作为修改和调整医疗专业人员测量CESoN性能质量的仪器的先驱,这篇综述旨在确定,评估,综合并绘制支撑当前实践的证据和理论以及CESoN的程序要素。
    方法:本综述将遵循JoannaBriggsInstitute的范围审查方法以及CampbellCollaboration关于系统证据映射的建议。基于研究问题,人,概念,背景框架将用于制定纳入审查的资格标准。合格信息应通过搜索包括PubMed、护理和相关健康文献的累积指数,还有Scopus,以及专家机构发布的新生儿检查和筛查指南(例如,国家健康与护理卓越研究所,美国儿科学会,皇家儿科与儿童健康学院)和灰色文献。这项研究将包括主要和次要研究论文,循证指南,以及2013年至2023年9月以英文发表的专家文本和意见。
    背景:本范围审查和系统证据映射不需要伦理批准。这项研究的结果将通过同行评审的形式传播,也就是说,会议记录和同行评审的医疗保健期刊。
    BACKGROUND: All newborns undergo a Complete Examination and Screening of the Neonate (CESoN) to verify the general health and well-being of the neonate and to screen for signs and symptoms of illness and significant congenital disorders, typically within 72 hours of birth. For healthy, term gestation neonates, this examination is usually performed by a qualified healthcare practitioner that is, a midwife, nurse or physician just prior to discharge from the maternity services. As a precursor to modifying and adapting an instrument that measures the quality of performance of the CESoN by healthcare professionals, this review aims to identify, evaluate, synthesise and map the evidence and theory underpinning current practice and the procedural elements of the CESoN.
    METHODS: This review will be guided by the Joanna Briggs Institute methodology for scoping reviews and also the recommendations of the Campbell Collaboration for systematic evidence mapping. Based on the research question, the Person, Concept, Context framework will be used to develop eligibility criteria for inclusion in the review. Eligible information shall be sourced by searching electronic databases including PubMed, Cumulative Index of Nursing and Allied Health Literature, and Scopus, and the published guidance from expert bodies on newborn examination and screening (eg, National Institute for Health and Care Excellence, American Academy of Pediatrics, Royal College of Paediatrics and Child Health) and the grey literature. This study will include primary and secondary research papers, evidence-based guidelines, and expert text and opinions published in English from 2013 to September 2023.
    BACKGROUND: Ethical approval is not required for this scoping review and systematic evidence mapping. The results from this study will be disseminated through peer-reviewed format, that is, conference proceedings and peer-reviewed healthcare journals.
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  • 文章类型: Journal Article
    背景:模拟是一种在医疗保健教育中越来越多地使用的技术,它提供了评估护理熟练程度的机会。使用有效和可靠的工具被认为是可靠评估的基础,然而,研究生护士基于能力的健康评估课程可以成为衡量熟练程度的简化者。
    目标:具体的复习问题是:在基于模拟的教育中,评估研究生护理学生获得健康史和患者评估表现的能力的标准是什么?
    方法:本综述纳入了11项研究。论文通过JoannaBriggs研究所准实验研究清单进行了严格评估。布卢姆的分类法被用来构建这篇叙述性评论。
    结果:七篇论文通过问卷评估认知,两篇论文使用李克特量表来确定自我感知知识。六篇论文用行为清单评估了精神运动技能。在测试情感技能时,应用的多样性被纳入研究。三篇论文使用了李克特量表来评估准备情况,六篇论文使用Likert量表来评估自信心,一篇论文使用Likert量表来评估自主性。三篇论文使用清单来评估专业水平。四篇论文使用了教职员工/标准化的患者反馈。
    结论:还原论评估工具在评估能力时会造成障碍。仿真中评估仪器的有效性和可靠性有限,以及情感技能评估缺乏标准化,对仿真研究提出了挑战。情感技能包括态度,行为和沟通能力,由于其主观性,这对标准化评估构成了重大挑战。对仿真文献的回顾强调了情感领域评估中缺乏鲁棒性。本文提出模拟评估工具应包括情感领域熟练程度的标准化,例如:适应患者的认知功能,解释和综合相关信息的能力,证明临床判断的能力,准备采取行动,对专业局限性和教师/标准化模拟患者反馈的认识。将情感领域纳入标准化评估工具对于确保对模拟进行全面评估非常重要,特别是在健康史和身体评估熟练程度的发展中。在模拟评估期间注意Blooms分类法中的所有领域,有可能为患者护理环境更好地准备专业人员。
    BACKGROUND: Simulation is a technique being used increasingly in healthcare education which offers opportunities to evaluate nursing proficiencies. The use of valid and reliable instruments is recognised as the foundation for a robust assessment, however competency-based health assessment courses for graduate nurses can consequently become reductionist in measuring proficiencies.
    OBJECTIVE: The specific review question was: In simulation-based education, what are the criteria that evaluate graduate nursing student\'s competence in obtaining a health history and performance of patient assessment?
    METHODS: Eleven studies were included in the review. Papers were critically appraised with The Joanna Briggs Institute quasi-experimental studies checklist. Bloom\'s taxonomy was used to structure this narrative review.
    RESULTS: Seven papers evaluated cognition through questionnaires and two papers used a Likert-scale to determine self-perceived knowledge. Six papers evaluated psychomotor skills with a behavioural checklist. Diversity of application was factored into the studies when testing affective skills. Three papers used Likert-scales to evaluate preparedness, six papers used Likert-scales to evaluate self-confidence and one used a Likert-scale to evaluate autonomy. Three papers used a checklist to evaluate professionalism. Four papers used faculty member/ standardised patient feedback.
    CONCLUSIONS: Reductionist evaluation instruments create a barrier when evaluating competency. The limited validity and reliability of assessment instruments in simulation, as well as the lack of standardisation of affective skills assessment, presents a challenge in simulation research. Affective skills encompass attitudes, behaviours and communication abilities, which pose a significant challenge for standardised assessments due to their subjective nature. This review of the simulation literature highlights a lack of robustness in the evaluation of the affective domain. This paper proposes that simulation assessment instruments should include the standardisation of affective domain proficiencies such as: adaptation to patients\' cognitive function, ability to interpret and synthesise relevant information, ability to demonstrate clinical judgement, readiness to act, recognition of professional limitations and faculty/standardised-simulated patient feedback. The incorporation of the affective domain in standardised assessment instruments is important to ensure comprehensive assessment of simulation particularly in the development of health history and physical assessment proficiencies. Attention to all of the domains in Blooms taxonomy during simulation assessment has the potential to better prepare professionals for the patient care setting.
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  • 文章类型: Review
    目的:本研究旨在系统回顾评估成人呼吸功能失调(DB)的结局指标的心理测量特性。
    方法:包括关于开发和评估测量特性以评估DB的研究。该研究调查了1990年至2022年2月之间发表的实证研究,并于2023年5月在Cochrane图书馆系统评价数据库和Cochrane中央对照试验登记册中进行了更新搜索。OvidMedline(完整),OvidExcertaMedica数据库,奥维德联合药物和补充药物数据库,护理和相关健康文献的Ebscohost累积指数和物理治疗证据数据库。纳入研究的方法学质量采用基于CONCEN的健康测量指标选择标准(COSMIN)偏倚风险检查表进行评估。数据分析和综合遵循COSMIN方法,以审查结果测量工具。
    结果:16项研究符合纳入标准,并确定了10项结果指标。使用COSMIN评估了这些结果测量的心理测量特性。奈梅亨问卷(NQ)是唯一对内容有效性有“足够”评级的结果衡量标准,内部一致性,信度和结构效度。所有其他结局指标均未报告患者组的内容有效性特征。
    结论:NQ在评估DB时显示出高质量的有效性和可靠性证据。我们的评论表明,使用NQ评估支气管哮喘和过度换气综合征患者的DB是有帮助的。在考虑将其用于临床之前,需要对其余结果指标进行进一步的心理测量特性评估。
    CRD42021274960。
    OBJECTIVE: This study aimed to systematically review the psychometric properties of outcome measures that assess dysfunctional breathing (DB) in adults.
    METHODS: Studies on developing and evaluating measurement properties to assess DB were included. The study investigated the empirical research published between 1990 and February 2022, with an updated search in May 2023 in the Cochrane Library database of systematic reviews and the Cochrane Central Register of Controlled Trials, the Ovid Medline (full), the Ovid Excerta Medica Database, the Ovid allied and complementary medicines database, the Ebscohost Cumulative Index to Nursing and Allied Health Literature and the Physiotherapy Evidence Database. The included studies\' methodological quality was assessed using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) risk of bias checklist. Data analysis and synthesis followed the COSMIN methodology for reviews of outcome measurement instruments.
    RESULTS: Sixteen studies met the inclusion criteria, and 10 outcome measures were identified. The psychometric properties of these outcome measures were evaluated using COSMIN. The Nijmegen Questionnaire (NQ) is the only outcome measure with \'sufficient\' ratings for content validity, internal consistency, reliability and construct validity. All other outcome measures did not report characteristics of content validity in the patients\' group.
    CONCLUSIONS: The NQ showed high-quality evidence for validity and reliability in assessing DB. Our review suggests that using NQ to evaluate DB in people with bronchial asthma and hyperventilation syndrome is helpful. Further evaluation of the psychometric properties is needed for the remaining outcome measures before considering them for clinical use.
    UNASSIGNED: CRD42021274960.
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  • 文章类型: Journal Article
    婴儿髋关节脱位的延迟诊断可能导致复杂的儿童手术,家庭生活中断,和过早的骨关节炎。
    评估临床检查在识别婴儿髋关节脱位方面的诊断准确性。
    CINAHL的系统搜索,Embase,MEDLINE,和Cochrane图书馆从每个数据库开始到2023年10月31日。
    纳入的9项研究报告了3个月或更小的婴儿的临床检查(指数测试)和诊断性髋关节超声(参考测试)的诊断准确性。使用超声评估的Graf方法对髋关节异常进行分类。
    使用合理临床检查量表来分配证据水平,并使用诊断准确性研究的质量评估工具来评估偏倚。使用个体髋部作为分析单位提取数据;当通过3个或更多的纳入研究评估临床检查时,数据被合并。
    灵敏度,特异性,并计算识别髋关节脱位的似然比(LRs)。
    在5项研究中通过临床检查和诊断超声筛查的婴儿中,髋关节脱位(n=37859髋)的患病率为0.94%(95%CI,0.28%-2.0%).有8项研究(n=44827髋)评估了Barlow动作和Ortolani动作(脱臼和重新定位不稳定的髋关节)的使用;动作的敏感性为46%(95%CI,26%-67%),特异性为99.1%(95%CI,97.9%-99.6%),正LR为52(95%CI,21-127),负LR为0.55(95%CI,0.37-0.82)。有3项研究(n=22472髋)评估了有限的髋关节外展,敏感性为13%(95%CI,3.3%-37%),特异性为97%(95%CI,87%-99%),正LR为3.6(95%CI,0.72-18),负LR为0.91(95%CI,0.76-1.1)。一项研究(n=13096臀部)评估了咔嗒声,灵敏度为13%(95%CI,6.4%-21%),特异性为92%(95%CI,92%-93%),正LR为1.6(95%CI,0.91-2.8),负LR为0.95(95%CI,0.88-1.0)。
    在对所有婴儿臀部进行髋关节发育不良筛查的研究中,髋关节脱位的患病率为0.94%.Barlow和Ortolani动作的正LR是与髋关节脱位可能性增加最相关的发现。髋关节外展受限或咔嗒声没有明确的诊断效用。
    Delayed diagnosis of a dislocated hip in infants can lead to complex childhood surgery, interruption to family life, and premature osteoarthritis.
    To evaluate the diagnostic accuracy of clinical examination in identifying dislocated hips in infants.
    Systematic search of CINAHL, Embase, MEDLINE, and the Cochrane Library from the inception of each database until October 31, 2023.
    The 9 included studies reported the diagnostic accuracy of the clinical examination (index test) in infants aged 3 months or younger and a diagnostic hip ultrasound (reference test). The Graf method of ultrasound assessment was used to classify hip abnormalities.
    The Rational Clinical Examination scale was used to assign levels of evidence and the Quality Assessment of Diagnostic Accuracy Studies tool was used to assess bias. Data were extracted using the individual hip as the unit of analysis; the data were pooled when the clinical examinations were evaluated by 3 or more of the included studies.
    Sensitivity, specificity, and likelihood ratios (LRs) of identifying a dislocated hip were calculated.
    Among infants screened with a clinical examination and a diagnostic ultrasound in 5 studies, the prevalence of a dislocated hip (n = 37 859 hips) was 0.94% (95% CI, 0.28%-2.0%). There were 8 studies (n = 44 827 hips) that evaluated use of the Barlow maneuver and the Ortolani maneuver (dislocate and relocate an unstable hip); the maneuvers had a sensitivity of 46% (95% CI, 26%-67%), a specificity of 99.1% (95% CI, 97.9%-99.6%), a positive LR of 52 (95% CI, 21-127), and a negative LR of 0.55 (95% CI, 0.37-0.82). There were 3 studies (n = 22 472 hips) that evaluated limited hip abduction and had a sensitivity of 13% (95% CI, 3.3%-37%), a specificity of 97% (95% CI, 87%-99%), a positive LR of 3.6 (95% CI, 0.72-18), and a negative LR of 0.91 (95% CI, 0.76-1.1). One study (n = 13 096 hips) evaluated a clicking sound and had a sensitivity of 13% (95% CI, 6.4%-21%), a specificity of 92% (95% CI, 92%-93%), a positive LR of 1.6 (95% CI, 0.91-2.8), and a negative LR of 0.95 (95% CI, 0.88-1.0).
    In studies in which all infant hips were screened for developmental dysplasia of the hip, the prevalence of a dislocated hip was 0.94%. A positive LR for the Barlow and Ortolani maneuvers was the finding most associated with an increased likelihood of a dislocated hip. Limited hip abduction or a clicking sound had no clear diagnostic utility.
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  • 文章类型: Systematic Review
    背景:腰骨盆感觉运动控制(SMC)受损被认为是下腰痛(LBP)复发和持续的潜在机制之一。因此,LBP患者的临床检查中经常包括腰盆腔SMC测试。
    目的:根据COSMIN指南,评估LBP患者临床评估的LumbopelvicSMC测试的收敛和已知组有效性。
    方法:系统评价方法:搜索了5个电子数据库,直到2023年12月。包括通过检查或触诊评估的LBP患者腰骨盆SMC测试的收敛或已知组有效性的研究。必须在LBP患者和无痛人群之间评估已知组的有效性。两名独立研究人员使用COSMIN偏见风险清单和修改后的分级方法评估了偏见和证据质量(QoE)的风险。分别。对于单个测试和测试集群,分别报告了已知组有效性的结果。
    结果:纳入12项研究(946名参与者)。三项研究调查了三个单一测试的收敛效度。关于已知群体的有效性,6项研究评估了6项单项测试,4项研究调查了2个测试群.只有一个测试,对趋同组和已知组进行了评估.显示足够收敛或已知群体有效性的测试的QoE(非常)低,而对于已知组有效性不足的单一测试或测试集群,QoE适中。
    结论:所有临床评估的具有足够收敛或已知组有效性的腰骨盆SMC测试的QoE(非常低)低。因此,应谨慎解释试验结果,目前不建议在临床决策中高度依赖这些结果.
    Impairments in lumbopelvic sensorimotor control (SMC) are thought to be one of the underlying mechanisms for the recurrence and persistence of low back pain (LBP). As such, lumbopelvic SMC tests are frequently included in the clinical examination of patients with LBP.
    To evaluate convergent and known-groups validity of clinically assessed lumbopelvic SMC tests in patients with LBP according to COSMIN guidelines.
    Systematic review METHODS: Five electronic databases were searched until December 2023. Studies examining convergent or known-groups validity of lumbopelvic SMC tests assessed via inspection or palpation in patients with LBP were included. Known-groups validity had to be assessed between patients with LBP and pain-free persons. Two independent researchers appraised risk of bias and quality of evidence (QoE) using the COSMIN Risk of Bias checklist and modified GRADE approach, respectively. Results for known-groups validity were reported separately for single tests and test-clusters.
    Twelve studies (946 participants) were included. Three studies investigated convergent validity of three single tests. Regarding known-groups validity, six studies evaluated six single tests and four studies investigated two test-clusters. For only one test, both convergent and known-groups were assessed. The QoE for tests showing sufficient convergent or known-groups validity was (very) low, whereas QoE was moderate for single tests or test-clusters with insufficient known-groups validity.
    All clinically assessed lumbopelvic SMC tests with sufficient convergent or known-groups validity had (very) low QoE. Therefore, test outcomes should be interpreted cautiously and strong reliance on these outcomes for clinical decision-making can currently not be recommended.
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  • 文章类型: Journal Article
    背景:预计未来初次和修正全膝关节置换术(TKA)病例的数量会增加。采用两种主要类型的茎固定方法中的任何一种都有各种优点和缺点-胶结或混合技术。这篇综述旨在通过比较放射学结果和重新修订率,研究修订TKAs的最佳固定方法。
    方法:自2010年以来,使用PubMed和CochraneLibrary进行了系统评价和荟萃分析,以确定明确比较骨水泥与混合固定翻修TKA技术之间结果的研究。至少随访24个月。本综述共纳入8项研究。Egger的测试和漏斗图的目视检查没有发现发表偏差。
    结果:放射学失败和松动没有统计学上的显着差异(OR0.79,CI0.37-1.66,I2=29%,p=0.22),重新修订的所有原因(OR1.03,CI0.73-1.44,I2=0%,p=0.56)和无菌修订(OR0.74,CI0.27-2.02,I2=0%,胶结技术和混合技术之间的p=0.41)。两种固定技术之间的功能和疼痛结果的比较在本荟萃分析中包括的研究中很大程度上相似。
    结论:尽管在修订TKA中倾向于杂交茎,目前的证据显示,骨水泥固定技术和混合固定技术的放射学结局和再修订率在很大程度上相似.
    BACKGROUND: The number of primary and revision Total Knee Arthroplasty (TKA) cases are expected to increase in future. There are various advantages and disadvantage to employing either of the two main types of stem fixation methods - cemented or hybrid technique. This review aimed to study the most optimal fixation method for revision TKAs by comparing radiological outcomes and re-revision rates.
    METHODS: A systematic review and meta-analysis was performed using PubMed and Cochrane Library from 2010 to identify studies explicitly comparing outcomes between cemented against hybrid fixation revision TKA techniques, with a minimum follow up of at least 24 months. A total of 8 studies was included in this review. Egger\'s test and visual inspection of the funnel plot did not reveal publication bias.
    RESULTS: There was no statistically significant difference in radiological failure and loosening (OR 0.79, CI 0.37-1.66, I2 = 29%, p = 0.22), all causes of re-revision (OR 1.03, CI 0.73-1.44, I2 = 0%, p = 0.56) and aseptic revision (OR 0.74, CI 0.27-2.02, I2 = 0%, p = 0.41) between cemented and hybrid techniques. Functional and pain outcomes compared between the two fixation techniques were largely similar across the studies included in this meta-analysis.
    CONCLUSIONS: Despite a trend favouring hybrid stems in revision TKA, current evidence revealed that radiological outcomes and re-revision rates are largely similar between cemented and hybrid fixation techniques.
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  • 文章类型: Meta-Analysis
    目的:主要目的是估计生活质量(QoL)的合并平均分(总计,精神和身体健康成分)在不安腿综合征(RLS)患者中。次要目的是评估:(I)RLS与QoL的差异控制组,(二)异质性和可能的来源;(三)调节变量。
    方法:PubMed中确定的研究,Scopus,WebofScience,包括2000年1月至2022年12月之间的ProQuest。采用纽卡斯尔渥太华量表评价方法学质量。协议是预先注册的(PROSPERO,CRD42023387318)。
    结果:27项研究(20121名参与者,包括12个国家)。QoL的校正汇总估计平均得分为47.92(27项研究,CI95%:43.11至52.72,范围为0-100,即低高QoL),并受出版年份的影响很小(每年增加0.89,p=0.12)。心理健康部分的校正汇总估计平均得分为47.32(17项研究,95%CI:43.12至51.51,范围0-100),并受RLS仪器的影响(最近版本有所下降,p=0.05)。身体健康部分的校正汇总估计平均得分为39.08(17项研究,95%CI:33.05至45.10,范围0-100),没有统计学上显著的主持人。与对照组相比,RLS患者的汇总估计QoL评分在统计学上显着降低,总QoL的标准化平均差(SMD)分别为-0.78,-0.57和-0.50(24项研究)。身体和心理健康组成部分(14项研究)。总QoLSMD受女性比例的影响。
    结论:RLS患者的生活质量较低,与对照组相比,统计学上显著降低。
    OBJECTIVE: The primary aim was to estimate the pooled mean score of quality of life (QoL) (total, mental and physical health components) among patients with Restless Legs Syndrome (RLS). Secondary aims were to assess: (I) QoL differences for RLS vs. control groups, (II) heterogeneity and possible sources; and (III) moderating variables.
    METHODS: Studies identified in PubMed, Scopus, Web of Science, and ProQuest between January 2000 and December 2022 were included. Methodological quality was assessed with Newcastle Ottawa Scale. The protocol was pre-registered (PROSPERO, CRD42023387318).
    RESULTS: Twenty-seven studies (20121 participants, 12 countries) were included. The corrected pooled estimated mean score of QoL was 47.92 (27 studies, CI 95 %: 43.11 to 52.72, range 0-100, i.e., low-high QoL) and was marginally affected by publication year (increased 0.89 by each year, p = 0.12). The corrected pooled estimated mean score of the mental health component was 47.32 (17 studies, 95 % CI: 43.12 to 51.51, range 0-100) and influenced by RLS instrument (decreased with recent versions, p = 0.05). The corrected pooled estimated mean score of the physical health component was 39.08 (17 studies, 95 % CI: 33.05 to 45.10, range 0-100), with no statistically significant moderator. The pooled estimated QoL scores were statistically significantly lower in RLS patients compared to control groups with standardized mean difference (SMD) of -0.78, -0.57 and -0.50 respectively for overall QoL (24 studies), physical and mental health components (14 studies). Total QoL SMD was affected by proportion of women.
    CONCLUSIONS: Low QoL was revealed among RLS patients, which was statistically significantly reduced compared to control groups.
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  • 文章类型: Journal Article
    这项研究的目的是提高对痴呆症不同类型和特征的理解,包括他们的症状,诊断和医疗,并针对每种特定类型的痴呆症提出各种基于证据的运动干预措施及其临床应用。理论综述包括对科学数据库PubMed/Medline中出版物的分析,Ebsco,Scielo,和Google。共发现177篇文章,其中84个进行了深入研究。由于各种形式的痴呆症的患病率预计将从2019年的5740万增加到2050年的1.528亿,因此需要个性化的治疗策略。这篇综述讨论了各种形式的痴呆症,包括他们的病理,诊断标准,和患病率。强调准确诊断和量身定制护理的重要性,以及体育锻炼改善痴呆患者认知功能的有效性。对于阿尔茨海默氏症,建议将药物疗法和运动相结合,以增强脑血流量和神经递质活性。改善路易体痴呆的认知和运动功能,建议采用药物和物理疗法相结合。为了治疗额颞叶痴呆,药物和运动的混合目的是情绪调节,包括有氧运动,和一个统一的协议,是建议的。对于轻度认知障碍,有氧运动和功能性运动对延缓认知能力下降和提高认知能力具有重要意义。总之,针对每种疾病类型的具体特征量身定制的个性化护理和治疗计划可以改善患有这种疾病的个人的生活质量,并有效管理这一日益严重的全球健康问题。
    The aim of this study is to enhance comprehension of the different types and features of dementia, including their symptoms, diagnosis and medical treatment, and to propose various evidence-based exercise interventions and their clinical applications tailored to each specific type of dementia. The theoretical review includes the analysis of publications in the scientific databases PubMed/Medline, Ebsco, Scielo, and Google. A total of 177 articles were found, of which 84 were studied in depth. With the prevalence of all forms of dementia projected to increase from 57.4 million in 2019 to 152.8 million in 2050, personalized treatment strategies are needed. This review discusses various forms of dementia, including their pathologies, diagnostic criteria, and prevalence rates. The importance of accurate diagnosis and tailored care is emphasized, as well as the effectiveness of physical exercise in improving cognitive function in dementia patients. For Alzheimer\'s, a combination of drug therapies and exercises is recommended to enhance cerebral blood flow and neurotransmitter activity. To improve cognitive and motor functions in Lewy body dementia, a combination of pharmacological and physical therapies is recommended. For managing frontotemporal dementia, a mix of medication and exercises aimed at emotion regulation, including aerobic exercises, and a unified protocol, is suggested. For mild cognitive impairment, aerobic and functional exercises are important in delaying cognitive decline and enhancing cognitive performance. In conclusion, individualized care and treatment plans tailored to the specific characteristics of each disease type can improve the quality of life for individuals with this condition and effectively manage this growing global health issue.
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