Peritoneal tuberculosis

腹膜结核
  • 文章类型: Case Reports
    背景:由于临床表现不明确,诊断腹膜结核具有挑战性,特别是在患有HIV/AIDS和结核病感染的免疫功能低下患者中。
    方法:一名印尼男子,26岁,主诉腹中绞痛和便秘。患者目前的状态表现出虚弱和苍白的症状,口腔念珠菌病,腹部臃肿,明显的不适,和变钝。腹水分析显示ADA增加(709U/L),并使用GeneXpertMTB/RIF检测结核分枝杆菌。腹部X射线和CT扫描的影像学检查显示小肠梗阻。他接受了肠道减压,疼痛控制,静脉液体复苏,和纠正电解质失衡的小肠梗阻,没有任何手术干预的指征。他还在密集阶段接受了2个月的一线ATD,在连续阶段接受了4个月的ATD。ATD给药后2周,患者开始每天服用抗逆转录病毒药物.他在6个月后表现出良好的预后。
    结论:腹膜结核的诊断具有挑战性,因为其表现不明确,一些病例在出现小肠梗阻等并发症时被发现。ADA测试和GenExpertMTB/RIF是及时诊断结核病的有用工具。建议在患有腹膜结核的HIV/AIDS患者中使用ARV治疗,ATD治疗后2周开始。
    结论:腹膜结核合并小肠梗阻和HIV/AIDS感染是一种罕见的病例,早期诊断和监测对成功治疗具有重要意义。
    BACKGROUND: Diagnosing peritoneal tuberculosis is challenging due to unspecific clinical manifestations, particularly in immunocompromised patients with HIV/AIDS and tuberculosis infections.
    METHODS: An Indonesian man, 26-years-old, complained of mid-abdominal colic and constipation. The patient\'s present state exhibited symptoms of weakness and paleness, oral candidiasis, a bloated abdomen, palpable discomfort, and shifting dullness. The ascitic fluid analysis showed increased ADA (709 U/L), and detected Mycobacterium tuberculosis using GeneXpert MTB/RIF. Radiographic examination from abdominal x-ray and CT scan revealed a small bowel obstruction. He received intestinal decompression, pain control, intravenous fluid resuscitation, and correction of electrolyte imbalance for small bowel obstruction without any indication for surgical intervention. He also receive first-line ATD for 2 months during intensive phase and 4 months for continuous phase. After a period of 2 weeks following the ATD administration, the patient began taking ARV medication on a daily basis. He showed a good prognosis 6 months following.
    CONCLUSIONS: The diagnosis of peritoneal tuberculosis is challenging due to its unspecific manifestation and some cases are identified when complications such as small bowel obstruction appear. The ADA test and GenExpert MTB/RIF are useful instruments for promptly diagnosing tuberculosis. It is suggested to use ARV treatment in individuals with HIV/AIDS who have peritoneal tuberculosis, starting 2 weeks following ATD treatments.
    CONCLUSIONS: Peritoneal tuberculosis with small bowel obstruction and HIV/AIDS infection is a rare case in which early diagnosis and monitoring play an important role in successful treatment.
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  • 文章类型: Case Reports
    结核病是一种最常影响肺部的传染病,由结核分枝杆菌在人与人之间传播引起的。腹膜结核是一种肺外形式的疾病,通常表现为腹水综合征,有或没有发烧,在总体状况改变的情况下,通常在流行地区。腹膜结核的诊断并不总是那么容易,因为临床症状通常是阴险且无特异性的。我们报告了一名18岁女性的腹膜结核病例,出现10天腹部体积逐渐增加并伴有呕吐和腹泻。
    Tuberculosis is an infectious disease that most often affects the lungs, caused by human-to-human transmission of Mycobacterium tuberculosis. Peritoneal tuberculosis is an extra-pulmonary form of the disease that usually manifests as an ascitic syndrome, with or without fever, in a context of altered general condition, often in endemic areas. The diagnosis of peritoneal tuberculosis is not always easy, as the clinical signs are often insidious and unspecific. We report a case of peritoneal tuberculosis in an 18-year-old female, who had presented for 10 days with a progressive increase in abdominal volume associated with vomiting and diarrhoea.
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  • 文章类型: Case Reports
    腹部结核(TB)仍然是全球重大的健康问题。特别是在北非和摩洛哥等地方性高的地区。尽管诊断方式有了进步,腹部结核的非特异性表现对及时诊断和治疗提出了挑战.这里,我们报告了一例来自摩洛哥的年轻人的腹部结核病,表现为急性腹痛和败血症的迹象。放射学检查显示提示肠穿孔并发腹膜结核的特征。紧急剖腹手术证实了诊断,然而,患者在术后死于晚期脓毒症。该病例强调了腹部结核诊断和治疗的复杂性,需要高度怀疑和多学科合作。随着外科技术的发展和持续的研究工作,优化早期发现和治疗腹部结核病的策略仍然势在必行,特别是在流行地区。
    Abdominal tuberculosis (TB) remains a significant health concern globally, particularly in regions with high endemicity such as North Africa and Morocco. Despite advances in diagnostic modalities, the nonspecific presentation of abdominal TB poses challenges for timely diagnosis and management. Here, we report a case of abdominal TB in a critically state of a young man from Morocco, presenting with acute abdominal pain and signs of sepsis. Radiological investigations revealed features suggestive of intestinal perforation complicating peritoneal TB. Urgent laparotomy confirmed the diagnosis, yet the patient succumbed to advanced sepsis postoperatively. This case underscores the complexity of abdominal TB diagnosis and management, necessitating a high index of suspicion and multidisciplinary collaboration. With evolving surgical techniques and ongoing research efforts, optimizing strategies for early detection and treatment of abdominal TB remains imperative, particularly in endemic regions.
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  • 文章类型: Journal Article
    已知腹膜结核(TB)模拟晚期卵巢癌。在这个案例报告中,我们描述了在国际妇产科联合会(FIGO)阶段IC1伴有肺和腹膜TB的卵巢癌(子宫内膜样癌3级)的独特病例,术前怀疑是晚期卵巢癌和肺结核并存。一名68岁的妇女表现出突出的腹部肿块和发烧。实验室调查,成像,痰液分析表明在FIGOIIIC期可能诊断为卵巢癌,以腹膜播散和主动脉旁淋巴结转移为特征,并发肺结核进一步复杂化。手术治疗包括全腹全子宫切除术,双侧输卵管卵巢切除术,和部分网膜切除术.术中,肿瘤位于右卵巢,腹膜明显增厚,粘连提示腹膜结核。手术完成无明显并发症。术后组织病理学评估证实右侧卵巢3级子宫内膜样癌以及腹膜结核的证据。考虑到结核病的粘连程度,淋巴结清扫分期被认为具有挑战性,因此没有进行。在术后第2天开始抗结核治疗导致术前确定的肺结节和主动脉旁淋巴结肿大明显消退。表明它们的炎症源于结核病。尽管IC1期子宫内膜样癌3级患者通常主张术后化疗,但患者选择不进行化疗。因此,未给予辅助治疗,患者仍在密切观察.
    Peritoneal tuberculosis (TB) is known to mimic advanced ovarian cancer. In this case report, we describe a unique case of ovarian cancer (endometrioid carcinoma grade 3) at the International Federation of Gynecology and Obstetrics (FIGO) stage IC1 with pulmonary and peritoneal TB, which was suspected preoperatively to be a coexistence of advanced ovarian cancer and pulmonary TB. A 68-year-old woman presented with a prominent abdominal mass and fever. Laboratory investigations, imaging, and sputum analysis indicated a probable diagnosis of ovarian cancer at FIGO stage IIIC, characterized by peritoneal dissemination and para-aortic lymph node metastasis, which was further complicated by coexisting pulmonary TB. Surgical management included total abdominal hysterectomy, bilateral salpingo-oophorectomy, and partial omentectomy. Intraoperatively, the tumor was localized to the right ovary with significant peritoneal thickening and adhesions indicative of peritoneal TB. The surgery was completed without apparent complications. Postoperative histopathological evaluation confirmed grade 3 endometrioid carcinoma in the right ovary along with evidence of peritoneal TB. Given the extent of adhesions attributed to TB, lymph node dissection for staging was deemed challenging and was thus not pursued. Initiation of anti-TB treatment on postoperative day 2 resulted in marked regression of the preoperatively identified pulmonary nodules and para-aortic lymph node enlargement, suggesting their inflammatory origin from TB. Although postoperative chemotherapy is typically advocated for patients with stage IC1 endometrioid carcinoma grade 3, the patient opted against it. Consequently, no adjuvant therapy was administered and the patient remained under close observation.
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  • 文章类型: Case Reports
    腹膜淋巴瘤病是一种罕见的淋巴瘤表现,可以模仿腹膜结核。两种情况下的计算机断层扫描结果都包括网膜结块,增厚,和结节。我们报告了一名41岁的男子,他出现间歇性腹痛和腹胀。腹部CT最初提示腹膜结核是由于腹膜增厚和大网膜伴多个结节。然而,18F-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(18F-FDGPET/CT)图像显示增厚的腹膜中弥漫性代谢活性增加,网膜,和肠系膜.在超声引导下进行网膜活检,组织病理学检查显示高度伯基特淋巴瘤。区分腹膜淋巴瘤和结核至关重要,因为这两种情况的预后和管理有很大的不同。
    Peritoneal lymphomatosis is a rare presentation of lymphoma that can mimic peritoneal tuberculosis. The computed tomography findings in both conditions include omental caking, thickening, and nodularity. We report the case of a 41-year-old man who presented with intermittent abdominal pain and distension. Abdominal CT initially suggested peritoneal tuberculosis due to the thickening of the peritoneum and greater omentum with multiple nodules. However, 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) images showed diffuse metabolic activity increase in the thickened peritoneum, omentum, and mesentery. An omental biopsy was performed under ultrasonography guidance, and histopathological examination revealed a high-grade Burkitt lymphoma. It is crucial to distinguish peritoneal lymphomatosis from tuberculosis, as the prognosis and management of the two conditions are vastly different.
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  • 文章类型: Case Reports
    腹膜结核是一种罕见的结核形式,具有非特异性临床表现,可与几种消化性病变混淆。它还可以在腹膜癌病阶段模仿卵巢癌,因此,有时会引起诊断性腹腔镜检查的兴趣,这使得可以通过解剖病理学研究进行诊断。这是我们最初被诊断为卵巢癌的患者的情况,腹腔镜检查后腹膜结核的诊断得到了纠正。
    Peritoneal tuberculosis is a rare form of tuberculosis which gives a non-specific clinical picture which can be confused with several digestive pathologies. It can also mimic ovarian cancer at the stage of peritoneal carcinomatosis, hence the interest sometimes of a diagnostic laparoscopy which makes it possible to make the diagnosis which is confirmed by an anatomo-pathological study. This is the case of our patient who was initially diagnosed with ovarian cancer and the diagnosis was corrected in peritoneal tuberculosis after a laparoscopy.
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  • 文章类型: Case Reports
    背景:当腹痛患者需要考虑进行结核病检测时,腹膜结核很少见。
    方法:一名印尼女性,19岁,主诉腹痛和肿大。实验室检查异常,包括687,000/uL的血小板增多和3483U/mL的Ca-125。腹部超声和CT扫描显示盆腔囊性病变,腹部淋巴结肿大,和腹水。她被诊断为卵巢癌。患者接受了手术并获得了结节如结核瘤。结节活检结果提示肉芽肿性炎症。患者接受1类抗结核药物(ATD)治疗2个月,继续2类治疗7个月(共9个月)。预后改善,体重增加了15公斤(从40公斤增加到55公斤)。
    结论:腹膜结核的挑战是没有特定的体征和症状。因此,如果根据已出现的体征和症状进行治疗时,腹痛患者的结核病是地方性的,并且预后不佳,则必须考虑进行结核病检查。
    结论:应该在地方性结核病中评估结核感染的嫌疑,因为一些结核感染,如腹膜结核,没有具体的体征和症状。
    BACKGROUND: Peritoneal tuberculosis is rare when patients with abdominal pain need to be considered for tuberculosis testing.
    METHODS: An Indonesian female, 19 years old, complained of abdominal pain and enlargement. Laboratory examination is abnormal, including thrombocytosis of 687,000/uL and Ca-125 of 3483 U/mL. Ultrasound and CT scan of the abdomen showed cystic lesions in the pelvic cavity, enlargement of the abdominal lymph nodes, and ascites. She was diagnosed with ovarian carcinoma. The patient underwent surgery and obtained nodules such as tuberculoma. Nodule biopsy results showed granulomatous inflammation. The patient was given anti-tuberculosis drug (ATD) category 1 for 2 months and continued with category 2 for 7 months (total 9 months of treatment). The prognosis showed improvement, and weight increased by 15 kg (from 40 kg to 55 kg).
    CONCLUSIONS: The challenge of peritoneal tuberculosis is the absence of specific signs and symptoms. Therefore, tuberculosis testing must be considered if tuberculosis is endemic in patients with abdominal pain who do not show a good prognosis when treated according to the developed signs and symptoms.
    CONCLUSIONS: Suspicion of tuberculosis infection should be evaluated in endemic tuberculosis because some tuberculosis infections, such as peritoneal tuberculosis, do not have specific signs and symptoms.
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  • 文章类型: Case Reports
    腹膜结核(PTB)是一种罕见的临床疾病,经常无法诊断。PTB病例的稀缺强调了在临床环境中提高警惕性以检测其存在的必要性。值得注意的是,近年来,PTB发病率明显增加。结核分枝杆菌是引起PTB的病原体,影响多个胃肠道成分,如腹膜和肝胆系统。腹膜是结核病的罕见部位,具有广泛的非特异性症状。它可以是无症状的周期性症状或模仿积极的腹膜炎检查像我们的情况。
    方法:我们报道了一例19岁男性进行性腹痛。由于怀疑腹膜炎,广泛性压痛和体格检查的警惕促使我们进行紧急剖腹手术。在手术过程中,我们观察到腹膜表现出广泛的结节,类似于散布的播种模式,伴随着轻度腹水,这引起了我们对腹膜结核的怀疑.随后,腹水的细胞学分析和病变的组织病理学检查证实了我们对腹膜结核的诊断。
    我们分享了我们面对PTB的经验,并回顾了最近的论文,以找到更多相关信息。常见的介绍,可能的原因,讨论了影像学在诊断和管理中的作用,以获得更好的管理策略和最佳的手术决策。
    结论:腹膜结核是一种具有挑战性诊断的罕见疾病。主要症状包括呕吐,腹痛,腹水,减肥,和发烧。及时的识别和治疗对于取得更好的结果至关重要。
    UNASSIGNED: Peritoneal tuberculosis (PTB) is an infrequent clinical condition that frequently eludes diagnosis. The scarcity of PTB cases underscores the necessity for heightened vigilance within clinical settings to detect its presence. Notably, there has been a noticeable increase in PTB incidence in recent years. Mycobacterium tuberculosis is the causative agent responsible for PTB, affecting multiple gastrointestinal components such as the peritoneum and hepatobiliary system. Peritoneum is a rare site for TB with broad unspecific symptoms. It can be asymptomatic to periodic signs or mimic the positive peritonitis examinations like our case.
    METHODS: We have reported a case of 19-year-old male experiencing progressive abdominal pain. The presence of generalized tenderness and guarding on physical examination prompted us to perform an urgent laparotomy due to suspicion of peritonitis. During the surgery, we observed the peritoneum exhibiting widespread nodularity, resembling a disseminated seeding pattern, along with mild ascites, which raised our suspicion of peritoneal tuberculosis. Subsequently, cytological analysis of the ascitic fluid and histopathological examination of the lesions confirmed our diagnosis of peritoneal TB.
    UNASSIGNED: We have shared our experience in facing PTB and reviewed recent papers to find further relevant information. The common presentations, probable causes, the role of imaging in diagnosis and the management are discussed for better management strategy and the best surgical decision.
    CONCLUSIONS: Peritoneal tuberculosis is a rare condition with challenging diagnosis. Key symptoms include vomiting, abdominal pain, ascites, weight loss, and fever. Prompt recognition and treatment are vital for better outcomes.
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  • 文章类型: Case Reports
    腹膜结核(TB)是主要累及网膜的肺外结核类型之一,肝脏,肠道,脾,脾或女性生殖道。它有时会导致妇科相关的肿瘤学诊断,如晚期卵巢癌,由于其非特异性体征和症状,使得它很难被发现。本报告介绍了一例22岁的女性,该女性因排尿困难而出现了一个月的腹部疼痛和扩张的主要抱怨。进行了超声检查和磁共振成像,报告了一个大的单部位囊性盆腔腹部病变,可能是卵巢起源的,并考虑了双侧肾积水的肿瘤病因。为了确认诊断,进行了剖腹探查术,发现肺外腹部结核,并注册为直接观察治疗短程(DOTS),随后给予抗结核药物。总之,该病例报告强调了包膜腹膜结核作为卵巢肿瘤的伪装行为,以及它应该的事实,因此,在结核病仍然流行的地区的鉴别诊断中应该考虑,例如在发展中国家。因此,适当的诊断可以避免不必要的外科手术,适当的治疗可以挽救病人的生命。
    Peritoneal tuberculosis (TB) is one of the types of extrapulmonary TB that predominantly involves the omentum, liver, intestinal tract, spleen, or female genital tract. It can occasionally result in gynecological-related oncology diagnoses such as advanced ovarian cancer due to its non-specific signs and symptoms, making it very difficult to detect. This report presents a case of a 22-year-old female who presented with the chief complaints of pain and distension of the abdomen for one month with dysuria. Ultrasonography and magnetic resonance imaging was performed that reported a large uni-loculated cystic pelvic abdominal lesion likely to be of ovarian origin and suggestive of neoplastic etiology with bilateral hydroureteronephrosis. To confirm the diagnosis, an exploratory laparotomy was performed which revealed extrapulmonary abdominal TB, and was registered for Directly Observed Treatment Shortcourse (DOTS) following which anti-tubercular drugs were given. In conclusion, this case report highlighted the masquerading behavior of encysted peritoneal TB as an ovarian tumor, and the fact that it should, therefore, should be considered in the differential diagnosis in regions where TB remains endemic, such as in developing countries. Hence, an appropriate diagnosis can prevent the need for unnecessary surgical operations and adequate therapy can save the patient\'s life.
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  • 文章类型: Case Reports
    结核病在哥伦比亚是地方病,其肺形式在免疫活性宿主中的患病率很高,相反,腹膜受损是罕见且难以诊断的。
    一名住在农村地区的24岁女性患者出现体质和胃肠道症状到急诊科就诊,包括腹胀,腹泻,显著的体重减轻,夜间出汗,腹水逐渐发作并伴有腹痛。诊断检查,包括穿刺术,经阴道超声检查,腹部CT扫描,未提示恶性肿瘤或门脉高压。然而,诊断性腹腔镜检查显示,包括顶叶和盆腔腹膜,子宫,输卵管,大网膜提示腹膜结核。开始抗结核治疗,随后进行微生物学确认。
    结核病引起的腹部损害是一个诊断挑战,尤其是没有明显危险因素的患者。临床表现和临床旁数据可能没有特异性或不确定性,在明确确认之前需要腹膜活检和经验治疗。
    UNASSIGNED: Tuberculosis is endemic in Colombia, the prevalence of its pulmonary form in immunocompetent hosts is high, and peritoneal compromise instead is rare and difficult to diagnose.
    UNASSIGNED: A 24-year-old female patient living in a rural area presented to the emergency department with constitutional and gastrointestinal symptoms, including bloating, diarrhea, significant weight loss, nocturnal diaphoresis, and gradual onset of ascites with abdominal pain. Diagnostic workup, including paracentesis, a transvaginal ultrasound, and an abdominal CT scan, did not suggest malignancy or portal hypertension. However, diagnostic laparoscopy revealed a miliary pattern comprising the parietal and pelvic peritoneum, uterus, fallopian tubes, and major omentum suggestive of peritoneal tuberculosis. Anti-tuberculosis therapy was initiated with subsequent microbiological confirmation.
    UNASSIGNED: Abdominal compromise by tuberculosis is a diagnostic challenge, especially in patients with no apparent risk factors. The clinical manifestations and paraclinical data may be unspecific or inconclusive, requiring peritoneal biopsy and empirical treatment before definitive confirmation.
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