背景:患有癌症的儿童在治疗和存活期间处于营养不良的风险中。客观测量的味觉感知和自我报告的食物享乐主义是可能影响食物摄入的2个因素。
目的:这项双臂系统评价研究了化疗和放疗是否影响儿童和儿童癌症幸存者的(1)味觉和(2)享乐体验。
方法:在Medline进行了双臂系统文献检索,CINAHL,Embase,和PsychInfo数据库,直到2022年6月。癌症治疗对客观味觉或食物享乐主义的影响(即,食物的喜好或厌恶和食欲)进行了检查。
方法:以英文发表的包括儿童(年龄<18岁)或儿童癌症幸存者(任何年龄)的研究的同行评审文章进行了回顾。使用营养与饮食学会的证据分析库确定偏倚风险。
方法:共鉴定了口味搜索臂中的1417篇文章和享乐主义者搜索臂中的3862篇文章。其中,9和4篇文章有资格审查,分别。癌症治疗在治疗期间和存活期间对味觉感知具有高度可变的影响。接受化疗的儿童经历了习得性的食物厌恶,癌症儿童对肉类和咸味食物的喜好受到影响。治疗对食欲的影响各不相同。
结论:癌症治疗并不一致地影响味觉。食物喜好可能会受到负面影响,并且在癌症治疗期间可能会产生对食物的厌恶。建立儿童癌症治疗对味觉感知和食物享乐主义的临床相关性,需要更多的研究。
背景:PROSPERO注册号。CRD42020207127。
BACKGROUND: Children with cancer are at risk of poor nutritional status during treatment and into survivorship. Objectively measured taste perception and self-reported food hedonics are 2 factors that may influence food intake.
OBJECTIVE: This 2-armed systematic
review examined whether chemotherapy and radiotherapy affect (1) taste perception and (2) hedonic experiences of children and survivors of childhood cancer.
METHODS: A 2-armed systematic literature search was conducted in the Medline, CINAHL, Embase, and PsychInfo database until June 2022. The effects of cancer treatment on objective taste perception or food hedonics (ie, food liking or aversion and appetite) were examined.
METHODS: Peer-reviewed articles published in English of studies that included children (aged <18 years) or survivors of childhood cancer (any age) were reviewed. Risk of bias was determined using the Evidence Analysis Library by the Academy of Nutrition and Dietetics.
METHODS: A total of 1417 articles in the taste search arm and 3862 articles in the hedonics search arm were identified. Of these, 9 and 4 articles were eligible for
review, respectively. Cancer treatment had highly variable effects on taste perception during treatment and into survivorship. Learned food aversions were experienced by children receiving chemotherapy treatment and liking of meats and salty foods by children with cancer was affected. The impact of treatment on appetite varied.
CONCLUSIONS: Cancer treatment did not uniformly affect taste perception. Food liking may be negatively affected, and learned food aversions may develop during cancer treatment. To establish the clinical relevance of childhood cancer treatment on taste perception and food hedonics, more research is required.
BACKGROUND: PROSPERO registration no.CRD42020207127.