背景:苯甲醇在油漆和其他应用中用作剥离剂,苯甲醇中毒是症状,比如意识受损,呼吸抑制,低血压,代谢性酸中毒,肾功能不全.
方法:一名27岁的亚裔男子因接触含有苯甲醇的脱漆剂而严重意识障碍,被送往医院,乙二醇,和过氧化氢,他用来重新粉刷一座桥.患者在苯甲醇中毒镇静下接受治疗。住院第三天,他的腹部计算机断层扫描显示出麻痹性肠梗阻,所以他被转移到我们医院.多种物质的联合毒性,主要是苯甲醇,被认为是麻痹性肠梗阻的一个促成因素。抵达后,病人也有化学烧伤,高钠血症,和升高的生肌酶水平。入院时,他的尿马尿酸水平很高(14.9g/L)。我们对病人进行人工呼吸管理,同时避免高密度氧气,并通过胃管植入进行胃肠减压;还给予泻药。麻痹性肠梗阻在第4天好转,在第6天取出管子,患者在住院第11天出院。出院时未见明显并发症。
结论:据我们所知,这是第一例由苯甲醇引起的麻痹性肠梗阻,尽管多种因素可能影响了症状。通过吸入和皮肤吸收接触苯甲醇后,病人出现意识受损,代谢性酸中毒,麻痹性肠梗阻,尿马尿酸的升高导致了明确的诊断。
BACKGROUND: Benzyl alcohol is used as stripping agent in paints and other applications, and benzyl alcohol poisoning is indicated by symptoms, such as impaired consciousness, respiratory depression, hypotension, metabolic acidosis, and renal dysfunction.
METHODS: A 27-year-old Asian man was transported to a hospital for severe disturbance of consciousness following exposure to a paint stripper containing benzyl alcohol, ethylene glycol, and hydrogen peroxide, which he was using to repaint a bridge. The patient was treated under sedation for benzyl alcohol poisoning. On day 3 of hospitalization, his abdominal computed tomography scan revealed a paralytic ileus, so he was transferred to our hospital. The combined toxicity from multiple substances, mainly benzyl alcohol, was thought to be a contributing factor for the paralytic ileus. Upon arrival, the patient also had chemical burns, hypernatremia, and elevated myogenic enzyme levels. His urinary hippuric acid level was high (14.9 g/L) upon admission to the previous hospital. We treated the patient with artificial respiration management, while avoiding high-density oxygen, and with gastrointestinal decompression by gastric tube implantation; laxatives were also administered. The paralytic ileus improved on the 4th day, the tube was removed on the 6th day, and the patient was discharged on the 11th day of hospitalization. No apparent complications were observed at discharge.
CONCLUSIONS: To the best of our knowledge, this is the first
case report of paralytic ileus caused by benzyl alcohol, although multiple factors may have influenced the symptoms. After exposure to benzyl alcohol by inhalation and dermal absorption, the patient developed impaired consciousness, metabolic acidosis, and paralytic ileus, and the presence of elevated urinary hippuric acid led to a definitive diagnosis.