阴茎硬化性脂肪肉芽肿是一种相对罕见的疾病,与注射非法异物增加阴茎有关。我们的目标是报告临床表现,诊断,治疗,以及患有这种疾病的患者的结果,并回顾目前最相关的文献。
■自古以来就一直在向阴茎的皮下组织中注射矿物油以进行扩张。并发症的可能性早已为人所知,大多数医生已经放弃了这个程序。然而,它仍然在世界的一些地方实行。并发症可能是毁灭性的,包括死于栓塞或败血症。受影响的区域可能不限于注射部位,可能涉及阴囊和耻骨上区域。手术完全切除受累组织,然后用移植物或皮瓣覆盖裸露区域是最好的治疗选择。
■文献检索涉及阴茎、增强,扩大,硬化,脂肪肉芽肿,阴茎注射,石蜡瘤,并从诸如PubMed之类的数据库的计算机搜索中获得,Google搜索和Scopus。还描述了主要作者(BS)的个人经验。我们试图任意地将我们的搜索限制在包括与我们的审查主题相关的≥5名患者的文章中,因此,排除单个病例报告。然而,还发现并包括了对PubMed和Scopus的单一系统搜索。
■选择的治疗方法是彻底切除所有病变,然后进行皮肤移植。考虑到这种前景,随机化,对照研究被认为很难进行,显然,进一步的工作将继续基于个别外科医生的病例系列。至关重要的是,建议患者将神话与事实分开,并通过意识和教育采取预防措施,以最大程度地减少此问题的弊端。
UNASSIGNED: Sclerosing lipogranuloma of the penis is a relatively rare disorder associated with injection of illicit foreign materials for penile augmentation. We aim to report the clinical presentation, diagnosis, treatment, and outcomes of patients with this condition, and to review the most relevant literature currently available.
UNASSIGNED: Injection of mineral oil into the subcutaneous tissues of the penis for augmentation has been practiced since ancient times. The potential for complications has long been known, and most doctors have abandoned the procedure. However, it is still practiced in some parts of the world. The complications may be devastating including death from embolism or sepsis. The affected area may not be restricted to the injection site, potentially involving the scrotal and suprapubic areas. Surgery with complete removal of the involved tissue followed by covering the denuded area with a graft or skin flap is the best therapeutic option.
UNASSIGNED: The literature search involved keywords such as penis, augmentation, enlargement, sclerosing, lipogranuloma, penile injection,
paraffinoma, and was obtained from computerized search of databases such as PubMed, Google Search and Scopus. Personal experience of the lead author (BS) is also described. We tried arbitrarily to limit our search to articles including ≥5 patients pertaining to the subject of our review and, therefore, excluded single case reports. However, a single systematic search of PubMed and Scopus was also found and included.
UNASSIGNED: The treatment of choice is radical excision of all the lesions followed by skin grafting. Bearing in mind that prospective, randomized, controlled studies are considered difficult to carry out, further work will continue apparently to be based on case series by individual surgeons. It is critical to advise patients to separate the myths from the facts and use preventive measures through awareness and education to best minimize the downsides of this problem.