PET-MRI

PET - MRI
  • 背景:肺气肿性骨髓炎(EO)是一种极为罕见的由气体形成细菌引起的骨感染,文献中记载的病例很少。我们的研究旨在突出特征性成像特征,包括正电子发射断层扫描-磁共振成像(PET-MRI)在这种潜在致命实体的诊断中的新用途。
    方法:一名有近期腹主动脉手术史的36岁男性因持续背痛而进行骨盆X线摄影和计算机断层扫描(CT)。进行骶髂关节抽吸,随后进行PET-MRI随访。
    结果:X线摄影和CT显示双侧骶髂关节炎,骨性骨盆中的骨坏死和EO。左骶髂关节误吸确定金黄色葡萄球菌为病原体。PET-MRI显示EO伴左髂腰肌脓肿和腹主动脉移植物感染。在抗生素治疗和图像引导脓肿引流后,患者的症状得以缓解。
    结论:EO是骨髓炎的一种致命变种,缺乏已发表的病例。EO在射线照相中的相关成像特性,这里讨论CT和PET-MRI,以及围绕这种罕见情况的文献综述。
    Emphysematous Osteomyelitis (EO) is an extremely rare bone infection caused by gas-forming bacteria with few documented cases in the literature. Our study aims to highlight characteristic imaging features, including the novel use of positron emission tomographymagnetic resonance imaging (PET-MRI) in diagnosing this potentially fatal entity.
    Radiography and computed tomography (CT) of the pelvis were performed due to complaints of persistent back pain in a 36-year-old male with a history of recent abdominal aorta surgery. Sacroiliac joint aspiration was performed, and a follow-up PET-MRI was subsequently performed.
    Radiography and CT demonstrated bilateral sacroiliitis, osteonecrosis and EO in the bony pelvis. Left sacroiliac joint aspiration identified Staphylococcus aureus as the causative organism. PET-MRI revealed EO with left iliopsoas abscess and abdominal aortic graft infection. The patient\'s symptoms resolved following antibiotic therapy and image-guided abscess drainage.
    EO is a lethal variant of osteomyelitis with a dearth of published cases. Pertinent imaging characteristics of EO on radiography, CT and PET-MRI are discussed here, along with a review of the literature surrounding this rare condition.
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  • 文章类型: Journal Article
    胶质瘤是脑最常见的原发性肿瘤。它们可以分为II-IV级星形细胞瘤和II-III级少突胶质细胞瘤,根据他们的组织分子特征。预后和治疗高度依赖于分级和充分鉴定的预后和/或预测性分子标志物。多参数MRI,包括弥散加权成像,灌注,和MR光谱学,在胶质瘤特定分子亚群的非侵入性表征中显示出越来越高的价值。放射性标记的氨基酸类似物,如18F-FET,在神经胶质瘤成像中也被证明是有价值的。这些示踪剂不仅通过检测弥漫性神经胶质瘤的去分化区域而有助于诊断过程,但是这种技术在神经胶质瘤的随访中也很有价值,因为它可以区分假性进展和真正的肿瘤进展。由于多参数MRI和18F-FETPET是互补的成像技术,PET-MRI成像在原发性脑肿瘤的神经肿瘤成像中可能具有协同作用.这对两个初级分期都有价值,以及在治疗和随访期间。
    Gliomas are the most frequent primary tumors of the brain. They can be divided into grade II-IV astrocytomas and grade II-III oligodendrogliomas, based on their histomolecular profile. The prognosis and treatment is highly dependent on grade and well-identified prognostic and/or predictive molecular markers. Multi-parametric MRI, including diffusion weighted imaging, perfusion, and MR spectroscopy, showed increasing value in the non-invasive characterization of specific molecular subsets of gliomas. Radiolabeled amino-acid analogues, such as 18F-FET, have also been proven valuable in glioma imaging. These tracers not only contribute in the diagnostic process by detecting areas of dedifferentiation in diffuse gliomas, but this technique is also valuable in the follow-up of gliomas, as it can differentiate pseudo-progression from real tumor progression. Since multi-parametric MRI and 18F-FET PET are complementary imaging techniques, there may be a synergistic role for PET-MRI imaging in the neuro-oncological imaging of primary brain tumors. This could be of value for both primary staging, as well as during treatment and follow-up.
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  • 文章类型: Case Reports
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