Osteoma, Osteoid

骨瘤,骨样
  • 文章类型: Case Reports
    方法:一名15岁男性患者,有3周的活动引起的左大腿内侧疼痛病史,偶尔在休息时经历。病人否认夜间疼痛,发烧,或发冷。实验室调查显示以下正常值:血红蛋白水平为15.6g/dL(正常范围,13-16g/dL),血小板计数为240×103/微升(正常范围,140-440×103/微升),和7100个细胞/微升的白细胞总数(正常范围,4500-11000个细胞/微升)。中性粒细胞的百分比被认为是低的44%(正常范围,54%-62%),嗜酸性粒细胞的百分比略高,为3.7%(正常范围,0%-3%)。显示了左髋关节的前后X线照片。物理治疗开始了,治疗2周后无改善。患者被转介给骨科医生进行进一步评估。在体检时,患者认可明显的左髋关节疼痛,髋关节屈曲至90°,有限的内部和外部旋转(5°和15°,分别),和有利于左腿的止痛药步态。髋关节MRI和进一步的血清学分析需要进一步评估。尽管血清学检测是在外部实验室进行的,医生报告免疫球蛋白G莱姆滴度阳性,C反应蛋白水平正常,和正常的红细胞沉降率。要求盆腔CT。患者接受了一个疗程的强力霉素(100mg,每天两次,共28天),治疗开始后2周报告症状缓解。三周后,到我们科室就诊的病人反复出现左髋部疼痛,与最初的报告相比,严重程度相似。初次就诊后4个月,对左髋关节进行了第二次MRI检查。
    A 15-year-old male patient presented with a 3-week history of inner left thigh pain provoked by activity and experienced occasionally at rest. The patient denied nighttime pain, fever, or chills. Laboratory investigation revealed the following normal values: hemoglobin level of 15.6 g/dL (normal range, 13-16 g/dL), platelet count of 240 × 103/µL (normal range, 140-440 × 103/µL), and total leukocyte count of 7100 cells/µL (normal range, 4500-11 000 cells/µL). The percentage of neutrophils was considered low at 44% (normal range, 54%-62%), and the percentage of eosinophils was slightly high at 3.7% (normal range, 0%-3%). An anteroposterior radiograph of the left hip is shown. Physical therapy was initiated, with no improvement after 2 weeks of therapy. The patient was referred to an orthopedist for further evaluation. At physical examination, the patient endorsed marked left hip pain with hip flexion to 90°, limited internal and external rotation (5° and 15°, respectively), and antalgic gait favoring the left leg. Hip MRI and further serologic analysis were requested for further evaluation. Although the serologic testing was performed at an outside laboratory, the physician reported positive immunoglobulin-G Lyme titers, normal C-reactive protein level, and normal erythrocyte sedimentation rate. Pelvic CT was requested. The patient was prescribed a course of doxycycline (100 mg twice daily for 28 days), with reported resolution of symptoms 2 weeks after initiation of treatment. Three weeks later, the patient presented to our department with recurrent left hip pain, which was similar in severity compared with the initial presentation. A second MRI examination of the left hip was performed 4 months after the initial presentation.
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  • 文章类型: Review
    背景:骨样骨瘤(OO)是一种良性病变,其特征是骨髓中的纤维成分增加,髓腔内存在骨样结构,和周围的硬化骨缘。关于位于胫骨近端后部的OO的报道很少。
    方法:这里,我们报道了一个18岁男性的病例,入院评估右膝疼痛。右膝疼痛在6个月前开始,没有任何明显的原因,晚上特别严重,影响睡眠,并在爬楼梯或承重时加剧。患者还经历了屈曲疼痛。三维计算机断层扫描和磁共振成像显示,右胫骨后内侧平台的皮质骨下方有结节性病变,并且异常信号集中在右胫骨平台的后外侧,并伴有广泛的骨髓水肿。右膝关节囊中存在少量液体。患者随后接受了OO的关节镜切除。术后,疼痛明显减轻,膝盖的活动范围恢复正常.
    结论:尽管胫骨近端后部的OO很少发生,它可以通过微创关节镜可视化有效地切除。
    BACKGROUND: Osteoid osteoma (OO) is a benign lesion characterized by an increased fibrous component in the bone marrow, presence of bone-like structures within the medullary cavity, and a surrounding sclerotic bone rim. Reports on OO located in the posterior proximal tibia are rare.
    METHODS: Herein, we report the case of an 18-year-old male, admitted for the evaluation of right knee pain. The right knee pain had started 6 months prior without any apparent cause, which was notably severe at night, affecting sleep, and was exacerbated while climbing stairs or bearing weight. The patient also experienced pain on flexion. Three-dimensional computed tomography and magnetic resonance imaging revealed a nodular lesion beneath the cortical bone of the posterior medial plateau of the right tibia and an abnormal signal focus on the posterior lateral aspect of the right tibial plateau associated with extensive bone marrow edema. A small amount of fluid was present in the right knee joint capsule. The patient subsequently underwent arthroscopic excision of the OO. Postoperatively, there was significant relief of pain, and the knee range of motion returned to normal.
    CONCLUSIONS: Although OO in the posterior proximal tibia is a rare occurrence, it can be effectively excised through minimally invasive arthroscopic visualization.
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    文章类型: Review
    Ribbing\'s disease is a rare form of sclerosing bone dysplasia characterized by exuberant yet benign endosteal bone, and periosteum formation in the diaphysis of long bones. Diagnosis relies on exclusionary criteria, as the primary clinical manifestations entail progressive pain unresponsive to analgesic therapy, accompanied by serological markers within normal ranges. Pain management constitutes the cornerstone of treatment, with surgery appearing to offer the most efficacious approach, despite the absence of a standardized therapeutic algorithm. The diagnostic and therapeutic delays associated with Ribbing\'s disease, reaching up to 16 years, exert a profound impact on patients\' quality of life. Hence, the purpose of our work is to present a case report of Ribbing\'s disease and conduct a comprehensive literature review on the subject matter.
    La enfermedad de Ribbing es una forma rara de displasia ósea esclerosante caracterizada por una formación exuberante, aunque benigna, de hueso endóstico y periostio en la diáfisis de los huesos largos. El diagnóstico se basa en criterios de exclusión, ya que las manifestaciones clínicas principales implican dolor progresivo que no responde a analgésicos, acompañado de marcadores serológicos normales. El manejo del dolor constituye la piedra angular del tratamiento y la cirugía parece ofrecer el enfoque más efectivo, a pesar de no contar con un algoritmo terapéutico estandarizado. Los retrasos diagnósticos y terapéuticos asociados con la enfermedad de Ribbing, que pueden alcanzar hasta 16 años, impactan profundamente en la calidad de vida de los pacientes. Por lo tanto, el propósito de nuestro trabajo es presentar un reporte de caso de la enfermedad de Ribbing y realizar una revisión bibliográfica exhaustiva sobre el tema.
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  • 文章类型: Case Reports
    背景:骨样骨瘤是一种相对常见的良性骨形成性病变,通常发生在患有下肢和脊柱的年轻人中。它的特点是类骨组织的形成,骨头的前兆,并可在受影响地区引起疼痛和活动受限。手部和手指的骨样骨瘤很少见,因此代表了诊断挑战。患者的父亲提供了一份书面知情同意书,以发表并分享有关患者的所有图像和临床数据。
    方法:我们报告一例11岁女孩,她的左手食指持续疼痛和肿胀,以及有限的机动性,在1年的过程中。非甾体抗炎药缓解了疼痛,但一旦停药,它就会重新出现。
    方法:一系列调查,显示第二近端指骨颈部有溶解性病变,具有骨样骨瘤的特征。
    方法:切除植骨作为确定性治疗,病理证实骨样骨瘤诊断。然而,该患者在2年后因以前的症状复发而返回,进一步的测试表明骨样骨瘤复发。为了解决复发,使用了改良的开放式热消融技术.热消融是一种微创手术,利用热量破坏肿瘤细胞,它已被证明对治疗骨样骨瘤有效。改良的开放方法包括制作一个小切口以进入肿瘤,并通过先前CT引导的插入的克氏针直接将热量传递到受影响的区域。
    结果:患者报告术后1个月和1年无疼痛,没有复发的放射学迹象,表明病变完全切除。
    结论:总体而言,这个案例突出了诊断和治疗手和手指骨样骨瘤的挑战。需要进一步的研究来更好地了解根本原因,潜在风险因素,骨样骨瘤复发的最佳治疗方法。
    BACKGROUND: Osteoid osteoma is a relatively common benign bone-forming lesion that often occurs in young adults with a predilection for the lower limbs and spine. It is characterized by the formation of osteoid tissue, a precursor to bone, and can cause pain and restricted mobility in affected areas. Osteoid osteoma of the hand and fingers is rare, thus representing a diagnostic challenge. A written informed consent was provided from the patient\'s father for the publication and sharing all images and clinical data concerning the patient.
    METHODS: We are reporting a case of an 11-year-old girl who presented with persistent pain and swelling in her left index finger, as well as limited mobility, over the course of 1 year. Nonsteroidal anti-inflammatory drugs eased the pain, but it resurfaced once the medication was discontinued.
    METHODS: A series of investigations, showed a lytic lesion at the second proximal phalangeal neck, with features indicative of osteoid osteoma.
    METHODS: Excision with bone grafting was performed as definitive therapy with pathological confirmation of the osteoid osteoma diagnosis. Nevertheless, the patient returned 2 years later with a recurrence of her previous symptoms, and further tests suggested a recurrence of osteoid osteoma. To address the recurrence, a modified open thermoablation technique was used. Thermoablation is a minimally invasive procedure that uses heat to destroy the tumor cells, and it has been shown to be effective in treating osteoid osteoma. The modified open approach involves making a small incision to access the tumor and delivering heat directly through a previously CT-guided inserted Kirschner wire to the affected area.
    RESULTS: The patient reported no pain at 1 month and 1 year after the surgery, with no radiological signs of recurrence, indicating complete excision of the lesion.
    CONCLUSIONS: Overall, this case highlights the challenges of diagnosing and treating osteoid osteoma in the hands and fingers. Further research is needed to better understand the underlying causes, potential risk factors, and optimal treatment for osteoid osteoma recurrence.
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  • 文章类型: Case Reports
    骨样骨瘤是一种发病率低的良性成骨性肿瘤。由于其罕见且经常令人困惑的临床表现,准确的诊断经常被显著延迟。我们报告了一例56岁的右撇子妇女,她的右肩胛骨(STT)关节和radial远屈腕肌(FCR)疼痛加重。由于其令人困惑的临床表现,诊断为舟骨骨旁骨样骨瘤和FCR破裂,表现为Manner感觉像病变,被推迟了1年。患者接受手术探查和切除治疗。在后续行动中,2周后,患者疼痛完全缓解,恢复了日常生活活动.高度怀疑仍然是诊断骨样骨瘤的关键点,当然是在这种情况下的异常临床表现和解剖定位的情况下。
    Osteoid osteoma is a benign osteoblastic tumor with a low incidence. Due to its uncommon and often confusing clinical presentation, accurate diagnosis is frequently significantly delayed. We report a case of a 56-year old right-handed woman with a history of increasing pain in her right scaphotrapeziotrapezoidal (STT) joint and distal flexor carpi radialis (FCR). Due to its confusing clinical presentation, the diagnosis of a parosteal osteoid osteoma in the scaphoid and a rupture of the FCR, presenting as a Mannerfelt like lesion, was delayed for 1 year. The patient was treated with surgical exploration and excision. At follow-up, the patient recovered with complete resolution of pain and resumed daily life activities after 2 weeks. A high index of suspicion remains the key point in the diagnosis of osteoid osteoma, certainly in cases of unusual clinical presentation and anatomic localization as presented in this case.
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  • 文章类型: Review
    楔形骨的骨样骨瘤是一种极为罕见且容易引起脚痛的原因。这种关节内骨样骨瘤的非特征性和非特异性X光片进一步增加了诊断的难度。迄今为止,在任何已发表的文献中,都没有关于中间楔形骨的关节内骨样骨瘤引起关节变性的描述。我们介绍了一例中间楔形骨的关节内骨样骨瘤,引起关节变性。接受刮宫的人,同种异体骨移植,和舟骨楔形关节固定术。患者表现为影像学骨愈合,在22个月的随访中,完全的运动功能恢复和无痛。此报告增加了现有文献。中间楔形骨的关节内骨样骨瘤导致关节变性是一种极为罕见且容易错过的脚痛原因。事实证明,识别关节内骨样骨瘤是一项复杂而具有挑战性的任务。临床医生应该特别小心,不要排除关节炎的可能性,因此,在选择手术时保持警惕。
    Osteoid osteoma of the cuneiform bone is an exceedingly rare and easily missed cause of foot pain. The uncharacteristic and nonspecific radiographs of such intra-articular osteoid osteoma further increase difficulty in making the diagnosis. To date, there has been no description of intra-articular osteoid osteoma of the intermediate cuneiform bone causing articular degeneration in any published literatures. We present a case of intra-articular osteoid osteoma of the intermediate cuneiform bone causing articular degeneration, who underwent curettage, allograft bone graft, and navicular-cuneiform arthrodesis. The patient presented with radiographic bone union, full motor function recovery and pain-free at the 22-month follow-up. This report adds to the existing literature. Intra-articular osteoid osteoma of the intermediate cuneiform bone causing articular degeneration is an exceedingly rare and easily missed cause of foot pain. It proves a complicated and challenging task to identify intra-articular osteoid osteoma. Clinicians should be particularly careful not to exclude the possibility of arthritis and, thus, vigilant when choosing the surgical option.
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  • 文章类型: Case Reports
    方法:一名29岁男子表现为非创伤性弥漫性胸痛。脊柱磁共振成像显示皮质病变伴周围高强度,一个中央硬化性低性病变,和周围的椎旁炎症改变在T3椎体。临床和放射学检查结果与骨样骨瘤一致。患者成功接受了内窥镜部分椎体切除和肿块切除。在6个月的随访中,X光片显示肿瘤完全消退。
    结论:对于骨样骨瘤的完整切除,内镜切除是一种足够的微创技术。
    A 29-year-old man presented nontraumatic diffuse thoracic pain. Magnetic resonance imaging of the spine showed a cortical lesion with peripheral hyperintensity, a central sclerotic hypointense nidus, and surrounding paraspinal inflammatory changes at the T3 vertebral body. Clinical and radiologic findings were consistent with an osteoid osteoma. The patient successfully underwent an endoscopic partial corpectomy and mass resection. At the 6-month follow-up, radiographs showed complete tumor resolution.
    Endoscopic resection is an adequate and minimally invasive technique for the complete resection of osteoid osteomas.
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  • 文章类型: Case Reports
    方法:一名22岁的男子长期服用,病因不明的进行性颈部疼痛。调查显示颈椎骨样骨瘤影响右C4-5小关节。他接受了O-arm辅助三维导航的微创整块切除术,而没有引起医源性脊柱不稳定。手术后症状缓解,在2年的随访中没有复发或不稳定。
    结论:颈椎骨样骨瘤是一种存在诊断和治疗挑战的肿瘤。实现精确,采用微创入路完全切除肿瘤,同时避免脊柱内固定和关节固定术对于获得良好的手术效果至关重要.
    A 22-year-old man presented with long-standing, progressive neck pain of unknown etiology. Investigation revealed a cervical spine osteoid osteoma affecting the right C4-5 facet joint. He underwent minimally invasive en bloc resection with O-arm-assisted 3-dimensional navigation without introducing iatrogenic spinal instability. Symptoms resolved after surgery, without recurrence or instability at the 2-year follow-up.
    Cervical spine osteoid osteoma is a tumor that presents diagnostic and therapeutic challenges. Achieving precise, complete resection of the tumor with a minimally invasive approach while avoiding spinal instrumentation and arthrodesis is paramount to excellent surgical outcomes.
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  • 文章类型: Case Reports
    目的:本病例报告的目的是表明椎体骨样骨瘤的晚期诊断会导致结构性脊柱侧凸,有时需要长期治疗。
    方法:我们报告一例与结构性脊柱侧凸相关的胸椎骨样骨瘤。我们描述了一个14岁的男孩,他抱怨慢性夜间左背痛和脊柱侧弯。脊柱X线报告胸腰段脊柱侧凸,无骨病变。
    结果:MRI以及tech-99m全身骨扫描和计算机断层扫描显示T11椎骨左上关节有骨性病变,与OO的诊断一致。切除片的解剖病理学研究证实了OO的诊断。肿瘤的手术切除解决了疼痛,但是脊柱侧弯需要矫形治疗1年。
    结论:通过这个案例,已经证明,晚期诊断的椎体OO可能是结构性脊柱侧凸的原因。临床和放射学结果表明,OO切除术是一种有效且安全的治疗方法。
    方法:IV.
    The aim of this case report is to show that late diagnosis of vertebral osteoid osteoma gives rise to structural scoliosis which sometimes requires long-term management.
    We report a case of an osteoid osteoma in the thoracic spine associated with structural scoliosis. We describe a 14-year-old boy who complained chronic nightly left back pain and scoliosis. Spine\'s X-ray was reported thoraco-lumber scoliosis without bone lesion.
    MRI as well as technetium-99 m total body bone scan and a computed tomography scan revealed a bony lesion in the upper left joint of T11 vertebra consistent with the diagnosis of OO. Anatomopathological study of the resection piece confirmed the diagnosis of OO. Surgical excision of the tumor resolved pains, but scoliosis needed an orthopedic treatment for 1 year.
    Through this case, it has been demonstrated that late diagnosed vertebral OO can be the cause of structural scoliosis. Clinical and radiological results indicate that OO resection is an effective and safe method of treatment.
    IV.
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  • 文章类型: Case Reports
    骨样骨瘤是一种良性但疼痛的骨肿瘤,其治疗基于完全手术切除。我们在此通过文献综述报告一例年轻的桡骨上肢骨样骨瘤患者。
    Osteoid osteoma is a benign but painful bone tumor whose treatment is based on complete surgical resection. We here report the case of a young patient with osteoid osteoma of the upper extremity of the radius through a literature review.
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