鳞状细胞癌(SCC)是最常见的口咽(OP)恶性肿瘤。治疗OPSCC包括化疗,辐射,和/或手术。OPSCC可以通过直接扩展传播,淋巴管,或造血。虽然罕见,远处转移可发生在OPSCC中。最常见的转移部位包括肺,骨头,还有肝脏.其他不太常见的部位包括皮肤,骨髓,大脑,肾脏,眼睛,和心脏。存在远处转移的患者通常预后不良。从较常见到较少见的骨转移部位包括脊柱,头骨,肋骨,和轴骨。在这篇文章中,我们讨论了一名患有HPV+舌根SCC并转移到肺部和下颌骨联合的患者。舌根SCC转移到下颌骨联合是很少报道的转移位置。
Squamous cell carcinoma (SCC) is the most common malignancy of the oropharynx (OP). Treatment of OP SCC includes chemotherapy, radiation, and/or surgery. OP SCC can spread via direct extension, lymphatics, or hematogenously. Although rare, distant metastases can occur in OP SCC. The most common sites of metastasis include the lungs, bone, and liver. Other less common sites include the skin, bone marrow, brain, kidneys, eyes, and heart. Patients who present with distant metastases usually have a poor prognosis. Sites of bone metastases from more common to less common include the spine, skull, ribs, and axial bones. In this article, we discuss a patient who presents with HPV+ base of tongue SCC with metastases to the lungs and mandible symphysis. Base of tongue SCC metastasizing to the mandible symphysis is a rarely reported location of metastasis.