背景:消费品,例如电动剃须刀,以压力和剪切的形式在皮肤上施加动态载荷的组合。这种机械刺激可能导致不适和皮肤组织反应,其特征为“皮肤敏感性”。为了将剃须后的不适降至最低,需要使用光学相干断层扫描(OCT)等先进工具建立特定的刺激-反应关系.
目的:探讨电剃刮刺激后皮肤形态和微血管功能的时空变化。
方法:招募10名健康男性志愿者。这项研究包括对前臂进行60秒的电剃刺激,脸颊和脖子。在基线时记录皮肤参数,刺激后20分钟和刺激后24小时。使用OCT估计结构和动态皮肤参数,同时记录了经皮水分流失(TEWL),以提供皮肤屏障功能的参考值。
结果:在基线时,八个参数中的六个显示了前臂和面部部位之间的统计学差异,而颊部和颈部之间仅表面粗糙度(Rq)和反射率有统计学差异(p<0.05)。剃须后20分钟,TEWL值显着增加,伴随着血液灌注的增加,变化幅度取决于解剖部位。刺激后24小时观察到恢复特征,大多数参数恢复到基础值,强调刺激的短暂影响。
结论:OCT参数显示皮肤组织对电剃的反应在空间和时间上存在差异。这种方法可以告知剃须刀设计并防止皮肤敏感。
BACKGROUND: Consumer products such as electrical shavers exert a combination of dynamic loading in the form of pressure and shear on the skin. This mechanical stimulus can lead to discomfort and skin tissue responses characterised as \"Skin Sensitivity\". To minimise discomfort following shaving, there is a need to establish specific stimulus-response relationships using advanced tools such as optical coherence tomography (OCT).
OBJECTIVE: To explore the spatial and temporal changes in skin morphology and microvascular function following an electrical shaving stimulus.
METHODS: Ten healthy male volunteers were recruited. The
study included a 60-s electrical shaving stimulus on the forearm, cheek and neck. Skin parameters were recorded at baseline, 20 min post stimulus and 24 h post stimulus. Structural and dynamic skin parameters were estimated using OCT, while transepidermal water loss (TEWL) was recorded to provide reference values for skin barrier function.
RESULTS: At baseline, six of the eight parameters revealed statistically significant differences between the forearm and the facial sites, while only surface roughness (Rq) and reflectivity were statistically different (p < 0.05) between the cheek and neck. At 20 min post shaving, there was a significant increase in the TEWL values accompanied by increased blood perfusion, with varying magnitude of change dependent on the anatomical site. Recovery characteristics were observed 24 h post stimulus with most parameters returning to basal values, highlighting the transient influence of the stimulus.
CONCLUSIONS: OCT parameters revealed spatial and temporal differences in the skin tissue response to electrical shaving. This approach could inform shaver design and prevent skin sensitivity.