目的:测量视盘玻璃疣(ODD)患者的视神经鞘直径(ONSD)和眼睛的前后轴长度。
方法:共纳入43名健康志愿者和41名ODD患者。使用频率为10MHz的超声设备(E-ZScanAB5500)探头在后部位置测量ONSD和轴向长度。ONSD是在地球壁后面3毫米处测量的。使用ONSD进行受试者工作特征(ROC)曲线分析以确定ODD患者。<0.05的任何p值被接受以证明显著性。
结果:ONSD明显更高(5.2mm和4.8mm,p=0.006,分别),轴向长度较短(21.82±2.15mm和23.27±1.96mm,在ODD组中分别为p=0.002)。在ODD组中,球形等效物更常见于远视(1.00[-0.85至1.75])。在ROC分析中确定ODD诊断中的ONSD值,曲线下面积为0.6754(95%置信区间0.559~0.788,p=0.006).5.70mm的ONSD截断值对诊断ODD的敏感性为0.366,特异性为0.907。
结论:在这项研究中,ODD组的ONSD明显较高.ODD组的轴向长度较短。这项研究是文献中第一个评估视盘玻璃疣患者的ONSD。在这方面需要进一步研究。
OBJECTIVE: Measuring the optic nerve sheath diameter (ONSD) and the anteroposterior axial length of the eye in patients with optic disc drusen (ODD).
METHODS: A total of 43 healthy volunteers and 41 patients with ODD were included in the
study. The ONSD and axial length were measured in the posterior position using an ultrasound device (E-Z Scan AB5500 +) probe with a 10 MHz frequency. The ONSD was measured 3 mm behind the globe wall. Receiver operating characteristic (ROC) curve analysis was performed to determine patients with ODD using ONSD. Any p-value of < 0.05 was accepted to demonstrate significance.
RESULTS: The ONSD was significantly higher (5.2 mm and 4.8 mm, p = 0.006, respectively), and the axial length was shorter (21.82 ± 2.15 mm and 23.27 ± 1.96 mm, p = 0.002, respectively) in the ODD group. The spherical equivalent was more commonly seen as hypermetropic in the ODD group (1.00 [- 0.85 to 1.75]). In the ROC analysis to determine the ONSD value in ODD diagnosis, the area under the curve was 0.6754 (95% confidence interval 0.559-0.788, p = 0.006). ONSD cutoff of 5.70 mm had a sensitivity of 0.366 and a specificity of 0.907 to diagnose ODD.
CONCLUSIONS: In this
study, the ONSD was significantly higher in the ODD group. The axial length was shorter in the ODD group. This
study is the first in the literature to evaluate the ONSD in patients with optic disc drusen. Further studies are needed in this regard.