Odontogenesis

牙本质发生
  • 文章类型: Journal Article
    背景:以前对牙齿发育异常(不是犬类异位)的幼儿的正骨图进行的一项研究表明,下颌犬齿的牙芽,与稳定的纵向犬轴相比,可以正常定位,前面或后面,与第一颗前磨牙有密切关系。
    目的:本研究的目的是分析正像图中的犬轴是否可以显示异位下颌犬齿开始形成牙齿的位置。
    方法:该材料包括47例(9-21岁29例,年龄不详18例)的异位下颌犬和原发性下颌犬的正位图。初级犬从轻微的根尖吸收到更严重的根尖吸收。
    方法:基于犬的成熟度,犬轴的位置以及恒牙和第一前磨牙的根之间的相互关系,确定了犬齿开始形成牙齿的位置。犬成熟。一半根长以下的成熟期和一半根长以上的成熟期显示,11例异位犬的根长小于一半,36例根长超过一半。犬齿轴。犬轴,穿过初级犬齿的长度,使用跟踪程序Inkscape®将其插入到正像图上。根之间的相互关系。通过目视检查,犬齿和第一前磨牙之间的距离被指定为近距离,正常距离和延伸距离。
    结果:结果分为3组。第1组:永久性异位犬的初始部位位于犬轴内(6例)。第2组:永久性异位犬的初始部位位于犬轴后方(36例)。第3组:永久性异位犬的初始部位位于犬轴前方(5例)。
    结论:该研究解释说,犬轴可以根据牙齿形成开始的位置将异位犬科病例分为三组。为了更接近异位犬喷发的模式,有必要分析几年来从同一个人身上拍摄的一系列正像图。
    BACKGROUND: A former study on orthopantomograms from young children with abnormal dental development (not canine ectopia) demonstrated that the tooth bud of the mandibular canine, compared to a stable longitudinal canine axis, could be located normally, anteriorly or posteriorly, with close relation to the first premolar.
    OBJECTIVE: The aim of the present study is to analyse on orthopantomograms if the canine axis can demonstrate where the ectopic mandibular canine started tooth formation.
    METHODS: The material consists of orthopantomograms with ectopic mandibular canines and presence of primary mandibular canines from 47 cases (29 cases 9-21 years old and 18 cases with unknown ages). The primary canines demonstrated from minor apical resorption to more severe apical resorption.
    METHODS: Based on canine maturity, location of the canine axes and the interrelationships between the roots of the permanent canine and first premolar, the location from where the canine started tooth formation was determined. Canine maturity. Maturity stage below half root length and maturity stage above half root length revealed that 11 ectopic canines had less than half root length and 36 cases more than half root length. Canine axes. The canine axis, through the length of the primary canines Ax, is inserted on drawings of the orthopantomograms using the tracing programme Inkscape®. Interrelationship between roots. By visual inspection, the distance between the canine and first premolar was designated close distance, normal distance and extended distance.
    RESULTS: The results are divided into 3 groups. Group 1: The initial site of the permanent ectopic canine is located within the canine axis (6 cases). Group 2: The initial site of the permanent ectopic canine is located posterior to the canine axis (36 cases). Group 3: The initial site of the permanent ectopic canine is located anterior to the canine axis (5 cases).
    CONCLUSIONS: The study explained that the canine axis could divide cases of ectopic canines into three groups according to the location from where tooth formation starts. For getting closer to the pattern of the ectopic canine eruption, it is necessary to analyse series of orthopantomograms taken from the same individual over several years.
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  • 文章类型: Case Reports
    鼻腔中存在多余牙齿(SNT)是一种罕见的情况,文献数据有限。我们报告了2例有鼻塞和呼吸困难史的病例。在这两种情况下,临床和放射学检查证实鼻内SNT。在全身麻醉中使用Rochester-Pean仪器经鼻进行提取。此外,对鼻内SNT进行了文献综述.从1970年到2020年,数据库搜索共检索到50例病例。患者平均年龄为22.5岁。最常见的症状是单侧呼吸阻塞和头痛。建议手术拔除鼻内SNT以消除症状。
    The presence of supernumerary tooth (SNT) in the nasal cavity is a rare condition with limited literature data. We report two cases with a history of nasal obstruction and difficulty breathing. In both cases, clinical and radiological examination confirmed intranasal SNT. Extractions were executed in general anesthesia using Rochester-Pean instruments transnasally. In addition, a literature review of intranasal SNT was performed. The database search retrieved a total number of 50 cases in time period from 1970 to 2020. Mean age of patients was 22.5 years. Most common symptoms were unilateral obstruction of breathing and headache. Surgical extraction of intranasal SNT is recommended to eliminate the symptoms.
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  • 文章类型: Systematic Review
    目的:磨牙切牙畸形(MRIM)是一种很少报道的疾病,其特征是第一恒磨牙的根部发育受到干扰。本系统综述旨在整理诊断为MRIM的个体的临床特征。
    方法:使用PubMed的系统搜索策略,Embase,WebofScience,和SCOPUS数据库一直进行到2023年3月。纳入标准是病例报告或病例系列,包括与MRIM一致的诊断。使用JoannaBriggsInstitute(JBI)病例报告和病例系列关键评估清单对所有纳入研究进行关键评估,并在JBI统一管理系统中对临床特征进行整理。评估和审查信息计划。
    结果:搜索确定了157项研究,其中35项符合纳入标准。经过全文审查,共有23篇论文描述了MRIM牙齿异常,并被纳入本文.共检索到130例报告病例,年龄在3-32岁之间,男性影响1.16:1女性。神经疾病的存在,早产史,药物,合成并描述了生命最初几年内的手术。
    结论:MRIM的病因尚未确定,但生命最初几年的重要病史的表观遗传变化可能会影响该根畸形的发展。第一恒磨牙最常见,但是临床医生应该意识到永久性中央切牙,乳牙和其他恒牙也可能受到影响。
    Molar-root incisor malformation (MRIM) is a seldom reported condition characterised by disturbances in root development of first permanent molars. This systematic review aimed to collate the clinical characteristics of individuals diagnosed with MRIM.
    A systematic search strategy using PubMed, Embase, Web of Science, and SCOPUS databases was performed through to March 2023. Inclusion criteria were case reports or case series including a diagnosis consistent with MRIM. Critical appraisal for all included studies utilised the Joanna Briggs Institute (JBI) critical appraisal checklist for case reports and case series and collation of clinical characteristics was performed in JBI System for the Unified Management, Assessment and Review of Information program.
    The search identified 157 studies from which 35 satisfied the inclusion criteria. After full-text review, a total of 23 papers described the MRIM dental anomaly and were included in this paper. A total of 130 reported cases were retrieved, with age ranging 3-32 years, and males affected 1.16:1 females. Presence of neurological conditions, premature birth history, medication, and surgery within first years of life were synthesised and described.
    The aetiology of MRIM is yet to be determined but epigenetic changes from significant medical history in the first years of life are likely to influence the development of this root malformation. First permanent molars were most commonly affected, but clinicians should be aware that permanent central incisors, primary teeth and other permanent teeth may also be affected.
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  • 文章类型: Case Reports
    背景:婴儿口腔残割(IOM),在东非广泛使用,涉及挖出未拔出的牙齿以据称治愈儿童疾病。在IOM期间经常使用非无菌器械,导致即时和长期并发症,包括牙齿缺陷,感染,和死亡。
    方法:这是一个案例报告,描述了IOM如何影响一名4岁的索马里女孩的牙齿发育和口腔健康,三年前,接受了她的原发性下颌犬的IOM。在4岁时从患者中提取了两个受影响的原发性下颌犬(表示为M*和R*),因为它们是畸形的,无功能,并有进一步病理的风险。牙齿M*受到中度影响,根长减少,根尖变钝,虽然牙釉质和牙本质厚度,密度,显微计算机断层扫描显示,组织组织在正常范围内。牙齿R*的大小急剧减小,并严重变形。根据组织学,在受影响的犬科动物中,牙本质小管在正常参数范围内,无细胞牙骨质薄,但矿物质密度未减少,组织学外观正常。永久性犬科动物在X射线照片中似乎未受影响。
    结论:此病例表明IOM影响了初级犬齿的发生,虽然牙釉质的形成,尽管有创伤,牙本质和牙骨质仍在继续。进一步调查国际移民组织及其对口腔和全身健康的影响,有助于开展消除这种做法的宣传工作。
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  • 文章类型: Case Reports
    Dens invaginatus (DI) is a developmental anomaly as a result of a deepening or invagination of the enamel organ into the dental papilla during tooth development. In addition, DI is a malformation with varying anatomical features, which poses numerous challenges to treatment. Endodontic treatment of dens in dente is one of the most complica-ted cases of DI. Herein, an immature lateral incisor that employed regenerative endodontic treatment was presented. The mentioned tooth was diagnosed with DI, pulp necrosis, and chronic apical periodontitis. Hence, a favorable prognosis has been shown by a 2-year review with cone beam computed tomography. The tooth was functional with normal periodontal parameters and exhibited a normal response to the electric pulp sensibility test. Thus, regenerative endodontic treatment can also be recommended to endodontists for teeth with DI.
    牙内陷是由牙发育时期成釉器过度卷叠或局部过度增殖,深入到牙乳头中而导致的牙齿形态异常,因其复杂的解剖结构,给常规的牙髓治疗带来困难和挑战。牙中牙的牙髓治疗为牙内陷最复杂的一种情况,本文报道1例上颌侧切牙年轻恒牙牙中牙伴根尖周炎的牙髓血运重建治疗的病例,结合锥形束CT的辅助诊断,对其治疗及预后进行评估。随访2年,牙根继续发育,根尖周炎症消失。本病例为年轻恒牙牙中牙的牙髓病及根尖周病提供了新的治疗策略。.
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  • 文章类型: Case Reports
    成釉细胞癌是一种恶性牙源性肿瘤,在兽医中很少有报道。提出了一个16岁的阿拉伯杂交母马,用于评估下颌骨上的硬块,X光片上有骨质溶解的证据.切开活检显示一种侵袭性肿瘤,由具有高有丝分裂计数和部分双重细胞角蛋白-波形蛋白免疫反应性的梭状样上皮细胞组成。由于出现后3个月的快速肿瘤进展,将马安乐死。尸检评估显示下颌骨部分消失,从公司到公司,棕褐色,局部破坏性和侵袭性肿块,无转移的大体或组织学证据。尸检组织学显示低分化的上皮肿瘤,具有不同的突出特征,提示牙源性组织发生:丛状带状结构,不常见的基底动脉与反基底动脉核,罕见的基底细胞质清除,上皮下基质透明化,和部分双重细胞角蛋白-波形蛋白免疫反应性。恶性肿瘤的特征包括坏死区域,明显的细胞异型,高的有丝分裂计数,广泛的组织侵入和局部组织破坏,肿瘤细胞延伸到下颌骨边缘之外。总的来说,这些特征与下颌成釉细胞癌最为一致。包括我们这里描述的案例,据报道,成釉细胞癌只有5匹马。报道最一致的微观特征是双重细胞角蛋白-波形蛋白免疫反应性,高的有丝分裂计数,和基底栅栏。成釉细胞癌应被视为快速生长的鉴别诊断,来自马齿状下颚的局部侵入性肿块。
    Ameloblastic carcinoma is a malignant odontogenic neoplasm that has been reported only rarely in veterinary species. A 16-y-old Arabian crossbred mare was presented for evaluation of a hard mass on the body of the mandible, with evidence of osteolysis on radiographs. Incisional biopsies revealed an invasive neoplasm comprised of spindloid epithelial cells with a high mitotic count and partial dual cytokeratin-vimentin immunoreactivity. The horse was euthanized because of rapid tumor progression 3 mo after presentation. Postmortem evaluation revealed partial obliteration of the mandible by a large, firm-to-hard, tan, locally destructive and invasive mass with no gross or histologic evidence of metastasis. Postmortem histology revealed a poorly differentiated epithelial neoplasm with variably prominent features suggestive of odontogenic histogenesis: a plexiform ribbon architecture, infrequent basilar palisading with antibasilar nuclei, rare basilar cytoplasmic clearing, subepithelial matrix hyalinization, and partial dual cytokeratin-vimentin immunoreactivity. Features of malignancy included regions of necrosis, pronounced cellular atypia, a high mitotic count, extensive tissue invasion and local tissue destruction, and extension of neoplastic cells beyond the margins of the mandibular bone. Collectively, these features are most consistent with mandibular ameloblastic carcinoma. Including our case described here, ameloblastic carcinoma has been reported in only 5 horses. The microscopic features reported most consistently are dual cytokeratin-vimentin immunoreactivity, a high mitotic count, and basilar palisading. Ameloblastic carcinoma should be considered as a differential diagnosis for rapidly growing, locally invasive masses arising from the dentate jaw of horses.
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  • 文章类型: Case Reports
    先天性颗粒细胞病变(CGCL)是婴儿罕见的良性口腔肿瘤。新生儿牙齿也是在生命的第一个月出现的罕见牙齿异常。本报告描述了CGCL手术切除后新生儿牙齿萌出的情况。令人惊讶的是,拔除新生儿牙齿后,残余的新生儿牙齿萌出。如果新生儿的牙齿是活动的,应小心地将它们拔除,刮除牙乳头的下层组织;如果不能刮除牙槽,可能会导致牙源性残留物的萌出。如果新生儿牙齿脱落,由于可能出现残留的新生儿牙齿,应告知父母需要定期与牙医进行检查。
    Congenital granular cell lesion (CGCL) is a rare benign oral cavity tumor in infants. Neonatal teeth are also rare dental anomalies that appear during the first month of life. This report describes a case of eruption of neonatal teeth after surgical excision of CGCL. Surprisingly, residual neonatal teeth erupted after extraction of the neonatal teeth. If neonatal teeth are mobile, they should be carefully extracted with curettage of the underlying tissues of the dental papilla; failure to curette the socket might result in eruption of odontogenic remnants. If neonatal teeth were exfoliated, parents should be informed of the need for regular checkups with a dentist due to possibility of development of residual neonatal teeth.
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  • 文章类型: Case Reports
    头痛是临床常见病,和适当的诊断和管理是口腔医生的一个挑战。鼻腔内任何微小的解剖变异都可能导致粘膜接触点,这可能是引起头痛的病因,并且在对头痛或面部疼痛患者进行初步评估时通常会被临床医生留下,导致误诊和不当治疗。本文试图介绍一例鼻源性接触点头痛,该头痛可能被误认为是牙痛,最初导致不正确的诊断和无关的治疗。一个彻底的,准确,全面的病史记录以及完整的临床和一般体检可正确诊断临床情况。
    Headache is a common clinical problem, and appropriate diagnosis and management are a challenge for oral physician. Any minor anatomical variation within the nasal cavity may lead to mucosal contact point, which may be an etiological factor for causing headache and often left behind by clinician during preliminary evaluation of patients with headache or facial pain, resulting in misdiagnosis and inappropriate treatment. This article is an attempt to present a case of rhinogenic contact point headache which may be mistaken for a toothache initially leading to incorrect diagnosis and irrelevant treatment. A thorough, accurate and comprehensive history taking and a complete clinical and general physical examination result in appropriate diagnosis of the clinical situation.
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  • 文章类型: Case Reports
    This study describes the clinical steps taken in the treatment of a patient who had an avulsed right upper central incisor that presented with incomplete root development and chronic apical periodontitis. A 7-year-old boy was referred from a private dentist to a dental office specializing in endodontics. The tooth had remained in a dry environment for 20 minutes, and tooth replantation was performed at an emergency appointment. After clinical and radiographic examinations, root canal decontamination was performed, followed by several changes in intracanal calcium hydroxide medication. Blood clot formation was attempted, but bleeding within the root canal was insufficient; therefore, we opted for an intracanal medication change to stimulate mineralized tissue formation in the apical region. Root obturation was performed 45 days after the last change of intracanal medication, and clinical, radiographic, and tomographic follow-up examinations were performed at 3, 6, 18, and 40 months after the endodontic intervention. The increase in thickness and length of the root structure and the absence of root resorption were verified through follow-up examinations. Therefore, it was concluded that the procedures used were successful for tooth replantation.
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  • 文章类型: Journal Article
    背景:在巴西,2015年10月,寨卡病毒(ZIKV)感染的爆发和小头畸形新生儿的增加表明母亲感染与儿童小头畸形之间存在关系。
    目标:首先,评估13名确诊为先天性ZIKV综合征的婴儿中牙芽的存在,母亲在怀孕期间感染了病毒;第二,在36个月的随访中评估这些儿童的牙齿发育。
    方法:基于案例的纵向研究。
    结果:第一学期的牙科X光片显示所有儿童都有牙芽。随着研究,这些人出现了各种牙齿紊乱。在评估期结束时,一些儿童仍然有不完整的乳牙。
    结论:感染ZIKV的小头畸形患儿的牙齿萌出和牙齿发育障碍的异常年代学表明,该病毒可能在牙齿发育中发挥作用。
    BACKGROUND: In Brazil, in October 2015, an outbreak of Zika virus (ZIKV) infection and an increase in newborns with microcephaly suggested a relationship between maternal infection and microcephaly in children.
    OBJECTIVE: First, to assess the presence of dental bud sin 13 infants with a confirmed diagnosis of congenital ZIKV syndrome, born to mothers infected with the virus during pregnancy; second, to evaluate the dental development of these children at a 36-month follow-up.
    METHODS: Case-based longitudinal study.
    RESULTS: Dental radiographs in the first semester showed that all children had dental buds. Along with the study, the individuals presented with various dental disturbances. At the end of the evaluation period, some children still had incomplete deciduous dentition.
    CONCLUSIONS: The abnormal chronology of dental eruption and dental development disturbances in children with microcephaly infected with ZIKV born to infected mothers indicate a possible role of the virus in odontogenesis.
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