重组蛋白为疾病治疗提供了新的手段,同时创造了可观的经济效益。使用商业作物（主要是烟草），谷类作物,豆类,和蔬菜作物生产具有药用价值的重组蛋白是“分子农业”研究的热点。尽管许多重组蛋白已在植物中表达,只有少数成功投入使用。为了克服严重阻碍植物重组蛋白生产发展的问题，研究人员改进了表达系统以提高重组蛋白的产量。从分析植物生产的重组蛋白产量低和/或生物活性低的问题出发，综述了解决这些问题的优化策略，并提出了提高植物产生的重组蛋白产量的未来研究方向。
Recombinant proteins provide new means for disease treatment, while creating considerable economic benefits. Using commercial crops (mainly tobacco), cereal crops, legumes, and vegetable crops to produce recombinant proteins with medicinal value is a hot-spot for research in \"molecular farming\". Although many recombinant proteins have been expressed in plants, only a small number have been successfully put into use. To overcome the problems that greatly hamper the development of recombinant protein production in plants, researchers have improved expression systems to increase the yield of recombinant proteins. Starting from analyzing the problems of low yield and/or low biological activity of recombinant proteins produced by plants, the optimization strategies to solve these problems were reviewed, and future research directions for improving the yield of recombinant proteins produced by plants were proposed.
