Neurogenic bladder

神经源性膀胱
  • 文章类型: Journal Article
    背景/目的:本研究旨在通过临床调查和尿动力学研究(UDSs)来确定颈椎或胸椎脊髓病患者的神经源性膀胱和相关症状的独特特征。方法:前瞻性招募计划进行减压手术的退行性颈椎(DCM)或胸(DTM)脊髓病和下尿路症状(LUTSs)患者。手术前一天进行UDS以评估术前泌尿系统功能。使用国际前列腺症状评分(IPSS)和日本骨科协会颈脊髓病评估问卷在手术前和术后一年评估主观症状。结果:纳入62例患者(DCM:50,DTM:12),平均年龄63.2岁(男性:30,女性:32)。UDS显示有5名(8.1%)患者,所有与DCM,表现出完全正常的UDS结果,其余57人至少有一个异常发现。根据国际连续性社会的分类,与DCM患者相比,DTM患者的膀胱活动不足明显更常见(75.0%vs.18.0%,p<0.001)。问卷结果显示排尿症状IPSS明显恶化,术前,在DTM患者中(5.0±4.4[DCM]vs.8.7±4.5[DTM];p=0.013)。术后一年,24.0%的DCM患者的IPSS等级得到改善,而只有1例(8.3%)DTM患者表现出改善。结论:与减压前DCM患者相比,DTM患者的排尿症状较差,并且在UDS上表现出更多的膀胱活动不足。术后一年,与DTM患者相比,DCM患者的排尿功能主观改善更多。
    Background/Objectives: This study aimed to identify the unique characteristics of neurogenic bladders and associated symptoms in patients with cervical or thoracic myelopathy using clinical surveys and urodynamic studies (UDSs). Methods: Patients with degenerative cervical (DCM) or thoracic (DTM) myelopathy and lower urinary tract symptoms (LUTSs) scheduled for decompressive surgery were prospectively enrolled. A UDS was performed one day preceding surgery to evaluate the preoperative urological function. Subjective symptoms were evaluated using the International Prostate Symptom Score (IPSS) and the Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire before surgery and one year postoperatively. Results: Sixty-two patients (DCM: 50, DTM: 12) with a mean age of 63.2 years (men: 30, women: 32) were enrolled. The UDS revealed that 5 (8.1%) patients, all with DCM, exhibited completely normal UDS results, and the remaining 57 had at least one abnormal finding. Based on the International Continence Society classification, an underactive bladder was significantly more common in patients with DTM compared to patients with DCM (75.0% vs. 18.0%, p < 0.001). The results of the questionnaire showed that the voiding symptom IPSS were significantly worse, preoperatively, in patients with DTM (5.0 ± 4.4 [DCM] vs. 8.7 ± 4.5 [DTM]; p = 0.013). One year postoperatively, the IPSS grade of 24.0% of patients with DCM improved, whereas only one (8.3%) patient with DTM showed improvement. Conclusions: Patients with DTM reported worse voiding symptoms and exhibited more underactive bladders on UDS than patients with DCM before decompression. One year postoperatively, more patients with DCM showed subjective improvements in urinary function than those with DTM.
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  • 文章类型: Case Reports
    膀胱造口术是膀胱出口挑战者不符合导管插入条件的患者的临时解决方案。一名73岁的男子使用膀胱造口术成功控制了膀胱59年。脱垂和皮炎的并发症导致73岁时膀胱造口术闭合和膀胱造口术。膀胱造口术可以安全地用于终生保护膀胱和上尿路健康。
    Vesicostomy is a temporary solution for patients with bladder outlet challenger who are not eligible for catheterization. A 73 year-old man who has successfully managed his bladder using a vesicostomy for 59 years. Complications of prolapse and dermatitis led to vesicostomy closure and cystostomy placement at age 73. Vesicostomy can be safely used to preserve bladder and upper urinary tract health for a lifetime.
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  • 文章类型: Case Reports
    由于功能原因导致的慢性尿潴留是一种难以治疗的病症。低压,低流量排尿功能障碍又称神经源性膀胱,是慢性尿潴留的常见功能原因。在这种情况下,传统的药物疗法并没有前途,对症治疗是通过定期导管插入术进行的。即使建议,由于其社会和医疗限制,导尿的停药率也很高。在这种情况下,在没有导尿的情况下,任何替代干预措施导致临床改善的可能性都伴随着对未来医学的希望。我们在这里介绍一个年轻女性由于神经源性膀胱而患有慢性尿潴留的病例,以前进行了几个月的定期间歇性导管插入术,随后通过旨在改善膀胱收缩力的阿育吠陀干预措施进行了治疗,以达到完全康复的程度,如果将此类观察结果带入认真的科学调查并转化为常规治疗策略,则对此类病例的治疗寄予厚望。针对类似的临床状况。
    Chronic urine retention due to functional reasons is a difficult to treat condition. Low-pressure, low-flow voiding dysfunction also called as neurogenic bladder is a common functional reason of chronic urinary retention. Conventional pharmacotherapy has not been promising in such conditions and the symptomatic management is done through regular catheterisation. Catheterisation due to its social and medical limitations has a high discontinuation rate even though if it is recommended. In this scenario, any possibility of alternative interventions leading to the clinical improvements without catheterisation comes with hope as a lead to the future medicine. We present here case of a young woman suffering with chronic urinary retention due to neurogenic bladder, previously on regular intermittent catheterisation for few months and subsequently treated through Ayurveda interventions aiming to improve bladder contractility to the extent of complete recovery raises a high hope for treating such cases if such observations are being brought to the serious scientific enquiry and are translated into regular treatment strategy for similar clinical conditions.
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  • 文章类型: Case Reports
    神经源性膀胱(NB)是中风后经常遇到的并发症,以症状为特征,如尿失禁,排尿困难,频率增加,和紧迫性。这里,我们介绍了一例75岁男性尿急,尿频,尿失禁,排尿时明显不适,中风后尿液中有难闻的气味。通过回顾患者以前的中风病历,排除膀胱功能障碍的其他潜在原因,可以建立NB的诊断。我们实施了传统的物理治疗,使用肌电图生物反馈装置进行盆底肌肉训练,和对对比区初级运动皮质区域的连续theta爆发刺激(cTBS)来管理膀胱功能。据我们所知,这是cTBS应用于卒中后NB管理的首例病例报告.我们的治疗在增强膀胱和肾功能方面表现出显著疗效,提高整体生活质量,并减轻该患者的焦虑和抑郁症状。本案例研究得出的结论是,当解决该特定患者群体时,非侵入性神经调节方法在临床领域显示出巨大的潜力。
    Neurogenic bladder (NB) is a frequently encountered post-stroke complication, characterized by symptoms, such as urinary incontinence, dysuria, increased frequency, and urgency. Here, we present a case of a 75-year-old male with urgent urination, frequent urination, urinary incontinence, conspicuous discomfort during urination, and an unpleasant smell in the urine following a stroke. By reviewing the patient\'s previous medical records of stroke and ruling out other potential causes for bladder dysfunction, a diagnosis of NB could be established. We implemented conventional physical therapy, pelvic floor muscle training with the electromyography biofeedback device, and continuous theta burst stimulation (cTBS) on the contralesional primary motor cortex area to manage bladder function. To the best of our knowledge, this is the first case report on cTBS applied to manage NB after stroke. Our treatment has demonstrated remarkable efficacy in enhancing bladder and kidney function, improving the overall quality of life, and alleviating anxiety and depression symptoms in this patient. This case study concludes that the noninvasive neuromodulation approach exhibits significant potential in the clinical field when addressing this specific patient population.
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  • 文章类型: Case Reports
    BACKGROUND: We present the first case of pediatric ileocystoplasty using a purely robotic approach in Spain.
    METHODS: 12-year-old male with neurogenic bladder of low capacity and high pressures. After failure of conservative treatment, bladder augmentation with ileum patch was decided upon. Surgery was carried out using a purely robotic approach with 4 robotic and 2 accessory ports. Surgery duration was 380 minutes in total, without intraoperative complications. He was discharged 2 weeks after cystographic control. During 32-months follow-up, he has remained continent.
    CONCLUSIONS: The minimal invasion, surgical precision and ergonomics made the robotic approach an optimal option for complex surgical techniques. Given the little availability of the robot and the low pediatric volume, its standardization is a challenge. Our accumulated experience is consistent with the current literature and shows promising surgical and esthetic results. We hope this case report will contribute to the divulgation and progressive introduction of robotic surgery in our daily lives.
    BACKGROUND: Presentamos el primer caso de abordaje robótico pediátrico puro en España.
    METHODS: Varón de 12 años con vejiga neurógena de escasa capacidad y altas presiones sin respuesta al tratamiento conservador, abogando por una ileocistoplastia de aumento. Se lleva a cabo un abordaje robótico puro con 4 puertos robóticos y 2 accesorios, de 380 minutos de duración total sin complicaciones intraoperatorias. Es dado de alta a las 2 semanas previo control cistográfico. Tras 32 meses de seguimiento continúa continente.
    UNASSIGNED: La mínima invasión, mayor precisión y ergonomía del abordaje robótico, hacen de éste una opción óptima para técnicas quirúrgicas complejas. Dada la difícil disponibilidad del robot y el escaso volumen pediátrico, resulta un reto su normalización en este campo. Nuestra experiencia coincide con la literatura, mostrando resultados quirúrgicos y estéticos prometedores. Esperamos este reporte contribuya a la difusión e introducción progresiva de la cirugía robótica en nuestra rutina.
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  • 文章类型: Case Reports
    本研究旨在调查作为良性和恶性脊柱疾病的初始表现的情况。重点是诊断中的挑战以及彻底的神经系统评估的重要性。
    我们进行了回顾性病例系列研究,涉及3名表现出膀胱收缩症状的患者。详细的临床病史,尿动力学研究,并对腰骶磁共振成像(MRI)等成像技术进行了分析。还考虑了相关活检的组织病理学发现。
    案例1:一名14岁女性出现尿潴留,背痛,和膀胱的尿动力学研究。进一步检查,包括腰骶MRI和组织病理学,确诊为转移性尤因肉瘤。病例2:一名39岁的女性尿失禁和排尿后残留物升高,表现出膀胱感觉延迟。腰椎MRI显示手术切除后为I级神经鞘瘤。病例3:在尿动力学研究中,一名15岁的男性下尿路症状和逼尿肌强肌,在腰骶部MRI上发现Tarlov囊肿。
    无张力或膀胱活动不足综合征可能是严重脊柱疾病的初始表现。如果没有明显的临床原因,则必须进行完整的神经系统评估。
    UNASSIGNED: This study aims to investigate cases of acontractile bladder as the initial presentation of benign and malignant spinal conditions. The focus is on the challenges in making a diagnosis and the importance of a thorough neurological evaluation.
    UNASSIGNED: We conducted a retrospective case series involving three patients who exhibited symptoms of acontractile bladder. Detailed clinical histories, urodynamic studies, and imaging techniques such as lumbosacral magnetic resonance imaging (MRI) were analyzed. Histopathological findings from relevant biopsies were also taken into account.
    UNASSIGNED: Case 1: A 14-year-old female presented with urinary retention, back pain, and an acontractile bladder on urodynamic study. Further examination, including lumbosacral MRI and histopathology, confirmed a diagnosis of metastatic Ewing\'s Sarcoma. Case 2: A 39-year-old female with urinary incontinence and elevated post-void residual exhibited delayed bladder sensation. Lumbar spine MRI revealed a grade I Schwannoma after surgical resection. Case 3: A 15-year-old male with lower urinary tract symptoms and an acontractile detrusor on urodynamic study was found to have a Tarlov cyst on lumbosacral MRI.
    UNASSIGNED: Atonic or Underactive bladder syndrome may be the initial presentation of a serious spinal condition. Complete neurological evaluation is mandatory if no obvious clinical cause.
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  • 文章类型: Case Reports
    静脉的外部压迫是单侧腿部水肿的相对罕见但重要的原因。这里,我们介绍了一例由于膀胱明显扩张引起的右髂静脉外部压迫引起的单侧右腿水肿,继发于神经源性膀胱。患者最初患有与慢性心力衰竭相关的双侧腿部水肿。然而,右腿水肿恶化并持续疼痛数天.下肢超声和计算机断层扫描显示膀胱扩大。基于这些发现,进行静脉造影和血管内超声检查.外部压迫是腿部水肿的重要原因。重要的是要考虑腹部/骨盆内过程的可能性,这可能导致单侧甚至双侧下肢肿胀的患者静脉系统的外部压迫。
    External compression of a vein is a relatively rare but important cause of unilateral leg edema. Here, we present a case of unilateral right leg edema caused by external compression of the right iliac vein due to a markedly distended urinary bladder, secondary to a neurogenic bladder. The patient initially had bilateral leg edema associated with chronic heart failure. However, the right-leg edema worsened and remained painful for several days. Lower extremity ultrasonography and computed tomography revealed an enlarged bladder. Based on these findings, venous angiography and intravascular ultrasound were performed. External compression is a significant cause of leg edema. It is important to consider the possibility of intra-abdominal/pelvic processes that may lead to external compression of the venous system in patients with unilateral and even bilateral lower extremity swelling.
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  • 文章类型: Case Reports
    神经源性下尿路功能障碍是脊髓损伤后的常见症状。这里,一名45岁的男性患者在脊柱手术期间因T12胸椎的跌倒骨折损伤而接受留置导尿管治疗,与下肢肌肉力量下降有关,被描述。在康复科住院期间,常规抗凝治疗,并在患者排尿时通过增加腹压拔除导尿管。拔除导尿管后第8天,该患者被发现左眼有轻微的结膜下出血,逐渐发展为双眼结膜下大量出血。重新留置导尿管后,双侧结膜下出血逐渐好转。复查凝血功能和血小板计数未发现异常指标,眼科检查结果正常。对于与脊髓损伤相关的神经源性膀胱功能障碍患者,在考虑通过腹压模式进行自发排尿时,应仔细评估抗凝期间的出血风险,以消除可能的潜在出血风险因素(包括既往病史和适当使用抗凝药物).
    Neurogenic lower urinary tract dysfunction is a common symptom after spinal cord injury. Here, the case of a 45-year-old male patient who was treated with indwelling urinary catheter during spinal surgery for a fall fracture injury of the T12 thoracic vertebra, associated with decreased muscle strength of both lower extremities, is described. During hospitalization in the rehabilitation department, conventional anticoagulation therapy was administered, and the urinary catheter was removed with the patient urinating by increasing abdominal pressure. At 8 days following urinary catheter removal, the patient was found to have a slight subconjunctival haemorrhage of the left eye, which gradually developed into massive subconjunctival haemorrhage in both eyes. After re-indwelling the urinary catheter, the bilateral subconjunctival haemorrhage gradually improved. No abnormal indicators were found during re-examination of coagulation function and platelet count, and the results of ophthalmological examination were normal. For patients with neurogenic bladder dysfunction associated with spinal cord injury, the risk of bleeding during the anticoagulation period should be carefully assessed to eliminate possible underlying bleeding risk factors (including past medical history and appropriate use of anticoagulant drugs) when considering spontaneous urination through the mode of abdominal pressure.
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  • 文章类型: Case Reports
    未经证实:紫色尿袋综合征(PUBS),最早描述于1978年,是尿液收集袋中出现紫色变色的罕见现象。本报告旨在提供PUBS的总体概述,其发病机制,和推荐的治疗方法。
    方法:一名女性患者,27岁,有先天性风疹感染史,主诉尿潴留。由于神经源性膀胱伴有下壁轻瘫,该患者常规进行foley导管检查1.5年。她还患有双侧下肢水肿,伤口感染两周,尿液袋中呈紫色尿液。实验室检查显示缺铁性贫血,低钾血症,和血碱中毒.
    未经证实:PUBS的紫色变色的原因是靛蓝的混合,蓝色颜料,还有靛玉红,红色颜料,这是饮食消化的结果,肝酶,和细菌尿液氧化。主要危险因素为女性患者,便秘,年龄较大,复发性UTI,肾功能衰竭,和导尿术,主要用于聚氯乙烯(PVC)导尿管或袋的慢性治疗。
    结论:管理应及时,严格,和适当的,因为复杂的UTI具有尿脓毒症的高风险进展。
    UNASSIGNED: Purple urine bag syndrome (PUBS), described first in 1978, is a rare phenomenon with purplish discolorations in the urine collecting bag. This report aims to provide a general overview of PUBS, its pathogenesis, and the recommended treatments.
    METHODS: A woman patient, 27 years old, with prior history of congenital rubella infection complained of urinary retention. The patient routinely had foley catheterization due to neurogenic bladder accompanied by paraparesis inferior for 1.5 years. She also suffered bilateral lower extremities edema with infected wounds for two weeks, which showed a purple urine color in the urine bag. The laboratory examination demonstrated iron deficiency anemia, hypokalemia, and blood alkalosis.
    UNASSIGNED: The cause of purplish discolorations of PUBS is the mixing of indigo, blue pigment, and indirubin, red pigment, which are results of dietary digestion, hepatic enzymes, and bacterial urine oxidation. The main risk factors are female patients, constipation, older age, recurrent UTI, renal failure, and urinary catheterization, dominantly on chronic treatment with polyvinyl chloride (PVC) urinary catheter or bag.
    CONCLUSIONS: The management should be promptly, rigorously, and appropriately because the complicated UTI has a high-risk progression of urosepsis.
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  • 文章类型: Case Reports
    未经证实:糖尿病神经源性膀胱(DNB)是糖尿病(DM)的自主神经病变之一,发病率达到40-60%。本研究结合膀胱功能康复训练和甲钴胺治疗1例DNB患者,为临床工作提供参考。
    UNASSIGNED:一名67岁妇女于2018年12月5日入院,有3年的排尿困难病史,并逐渐恶化15天。患者采用盆底肌筋膜手法结合Kegel训练和甲钴胺治疗6个月。盆腔器官脱垂(POP),盆底表面肌电图(EMG),心理状态,之前评估了生活质量,during,治疗后,观察尿动力学的变化。经过综合康复治疗,病人的POP,盆底肌肉力量,精神状态,生活质量明显改善。尿动力学检查结果显示,治疗后患者的安全膀胱容量达到500mL,与90mL的首次安全膀胱容量测量相反。输尿管反流症状消失,逼尿肌顺应性从2毫升/cmH2O增加到20毫升/cmH2O,这大致表明了健康功能的回归。然而,排尿期间膀胱中没有逼尿肌收缩。
    UNASSIGNED:该患者经盆底综合康复联合甲钴胺治疗后取得了良好的疗效。然而,在这种情况下报告的患者的安全容量显示膀胱安全容量较小,患者的逼尿肌在排尿时没有收缩。因此,该患者的排尿可以通过增加腹压来完成。在治疗非典型神经源性膀胱患者时,腹压过高和腹壁松弛引起的不良影响需要考虑。
    UNASSIGNED: Diabetic neurogenic bladder (DNB) is one of the autonomic neuropathies of diabetes mellitus (DM), with an incidence rate reaching 40-60%. This study combined bladder function rehabilitation training and mecobalamin to treat a patient with DNB to provide reference for clinical work.
    UNASSIGNED: A 67-year-old woman was admitted to our hospital on 5 December 2018, with a 3-year history of dysuria that had progressively worsened for 15 days. The patient was treated with pelvic floor myofascial manipulation combined with Kegel training and mecobalamin for 6 months. Pelvic organ prolapse (POP), pelvic floor surface electromyography (EMG), psychological status, and quality of life were evaluated before, during, and after treatment, and the changes in urodynamics were observed. After comprehensive rehabilitation treatment, the patient\'s POP, pelvic floor muscle strength, mental state, and quality of life were significantly improved. The results of the urodynamic examination showed that the patient\'s safe bladder capacity reached 500 mL after treatment, in contrast to the first safe bladder capacity measurement of 90 mL. The symptoms of ureteral reflux disappeared, the detrusor compliance increased from 2 to 20 mL/cmH2O, which roughly indicated a return to healthy function. However, there was no detrusor contraction in the bladder during urination.
    UNASSIGNED: This patient achieved good curative effect after the treatment of comprehensive pelvic floor rehabilitation combined with mecobalamin. However, the safe capacity of the patient reported in this case showed a small bladder safe capacity, and the patient\'s detrusor muscle did not contract during urination. Thus, urination in this patient may be accomplished by increasing abdominal pressure. When treating patients with atypical neurogenic bladder, the adverse effects caused by excessive abdominal pressure and abdominal wall relaxation need to be considered.
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