背景:糖尿病自主神经病变(DAN)是糖尿病(DM)的一种普遍但经常被忽视的并发症,影响多个器官,并大幅提高发病率和死亡率的风险。这项研究旨在评估基于瑜伽的干预(YBI)与美国糖尿病协会运动方案(ADAEx。方案)和治疗2型糖尿病自主神经病变的标准护理。
方法:这项开放标签的探索性临床试验有两个平行的研究组:A组(干预),与标准护理一起接受了YBI,B组,遵守ADAEx。制度与标准护理相结合。共有80名35-60岁的参与者,诊断为2型糖尿病和自主神经病变,被平均分配给两组。数据收集包括神经传导速度(NCV)测试,自主功能测试(AFTs),以及对抑郁和生活质量的评估。
结果:与ADAEx相比,YBI显示副交感神经张力下降。政权.经过六个月的干预,YBI组的交感神经活动指标(SD2)显示出比ADAEx明显更低的值。政权组,表明有积极的影响(p<0.05),而ADAEx.制度在NCV的某些领域显示出更多的改进(例如,左右腓骨NCV,右和左腓骨F延迟),碱性磷酸酶水平存在显著差异,抑郁评分,和WHO-5健康,均在p<0.05时达到统计学意义。
结论:研究发现,24周YBI可显著降低糖尿病性神经病变和应激的症状。虽然ADA前。与YBI相比,制度在NCV的特定方面表现出更大的改进,YBI的表现优于ADAEx。加强WHO-5健康和减少抑郁症状的制度。
BACKGROUND: Diabetic autonomic neuropathy (DAN) is a prevalent yet often overlooked complication of diabetes mellitus (DM), impacting multiple organs and substantially elevating the risk of morbidity and mortality. This
study aimed to assess the effectiveness of yoga-based intervention (YBI) compared to the American Diabetes Association exercise regimen (ADA Ex. Regime) and standard care for treating autonomic neuropathy in type 2 DM.
METHODS: This open-label exploratory clinical
trial featured two parallel
study arms: Group A (Intervention), which received YBI alongside standard care, and Group B, which adhered to the ADA Ex. Regime in conjunction with standard care. A total of 80 participants aged 35-60, diagnosed with type 2 DM and autonomic neuropathy, were equally allocated to both groups. Data collection included nerve conduction velocity (NCV) tests, autonomic function tests (AFTs), as well as evaluations of depression and quality of life.
RESULTS: YBI demonstrated a drop in parasympathetic tone compared to the ADA Ex. Regime. Following a six-month intervention, the sympathetic activity indicator (SD2) exhibited a significantly lower value in the YBI group than in the ADA Ex. Regime group, indicating a positive effect (p < 0.05), while the ADA Ex. Regime showed more improvement in certain areas of NCV (e.g., left and right peroneal NCV, right and left peroneal F-latency), notable differences were observed in alkaline phosphatase levels, depression scores, and WHO-5 wellness, all reaching statistical significance at p < 0.05.
CONCLUSIONS: The
study findings observed that a 24-week YBI significantly reduced in symptoms of diabetic neuropathy and stress. Although the ADA Ex. Regime demonstrated greater improvement in specific aspects of NCV compared to YBI, YBI outperformed the ADA Ex. Regime in enhancing WHO-5 wellness and reducing depression symptoms.