目的:报告眼科手术患者血源性病毒感染(BBVI)的血清阳性率,并评估印度目前的眼科护理系统术前筛查BBVI的实用性和可行性。
方法:本回顾性研究,以医院为基础,描述性研究包括接受术前筛查乙型肝炎病毒(HBV)患者的数据,丙型肝炎病毒(HCV),从2018年到2022年,三级眼科护理研究所的人类免疫缺陷病毒(HIV)。在获得患者知情同意后,对血液样本进行快速诊断测试(RDT)。血清反应性患者接受了额外安全预防措施的手术。收集并分析这些患者的人口统计学数据和手术细节。采用方差分析进行组间统计学分析。在学习期间,记录了在手术室(OT)遭受针刺伤(NSI)和意外锐器伤(ASI)的医护人员(HCWs)人数以及这些伤害的细节.
结果:包括来自28,563名患者的样本。BBVI的血清阳性率为1.87%(536/28563)。乙型肝炎病毒(322,60.1%)是最常见的感染,HIV(59,11%)是检测到的最少感染。血清反应性患者的平均年龄为60.3±30.8岁。NSI发生率为0.49/1000。OT中的护士(11)和技术人员(4)持续最大NSI。NSI后,所有HCW均无血清转化。
结论:本研究中BBVI的总体血清阳性率低于眼科护理组织先前发表的研究报告。目前,对BBVI进行强制性术前筛查,以防止这些感染传播给印度眼科护理部门工作的医护人员,其成本效益似乎较低.
OBJECTIVE: To report the seroprevalence of bloodborne viral infection (BBVI) in patients undergoing ophthalmic surgeries and assess the utility and feasibility of preoperative screening for BBVI in India\'s current eye care system.
METHODS: This retrospective, hospital-based, descriptive
study included data from patients undergoing preoperative screening for Hepatitis B virus (HBV), Hepatitis C virus (HCV), and human immunodeficiency virus (HIV) at a tertiary eye care institute from 2018 to 2022. Rapid diagnostic tests (RDTs) were performed on the blood samples after obtaining informed consent from the patients. Seroreactive patients underwent surgery with additional safety precautions. The demographic data and surgical details of these patients were collected and analyzed. ANOVA was used to carry out statistical analysis between groups. During the
study period, the number of healthcare workers (HCWs) sustaining needle stick injury (NSI) and accidental sharp injury (ASI) in the operating theater (OT) and details of these injuries were recorded.
RESULTS: Samples from 28,563 patients were included. The seroprevalence of BBVI was 1.87% (536/28563). Hepatitis B virus (322, 60.1%) was the most commonly detected infection, and HIV (59, 11%) was the least detected infection. The mean age of the seroreactive patients was 60.3 ± 30.8 years. The incidence of NSI was 0.49/1000 surgeries. Nurses (11) and technicians (4) in the OT sustained maximum NSI. None of the HCWs had seroconversion after NSI.
CONCLUSIONS: The overall seroprevalence of BBVI in the current
study is lower than that reported in previously published studies from eye care organizations. Currently, mandatory preoperative screening for BBVI to prevent transmission of these infections to HCWs working in the eye care sector in India appears to be less cost-effective.