未经证实:严重急性呼吸道综合症-冠状病毒-2(SARS-CoV-2)大流行对准妈妈及其婴儿的影响延伸到生活的许多方面。坏死性小肠结肠炎(NEC)已被认为是新生儿中威胁生命的胃肠道炎症过程,具有很高的发病率和死亡率。
UNASSIGNED:调查母亲为SARS-CoV-2阳性的住院新生儿中与NEC相关的因素及其与死亡率的关系。
UNASSIGNED:这项观察性研究于2020年5月至2021年3月进行。所有住院的新生儿,在确认母亲是SARS-CoV-2阳性后,包括在这项研究中。根据逆转录聚合酶链反应(PCR)测定确定SARS-CoV-2阳性。新生儿SARS-CoV-2测试在出生的第一天进行。NEC是根据提示的临床表现和异常的腹部X光片建立的。
未经证实:在这项研究中登记的125名新生儿中,有5例新生儿发生NEC,只有1例存活.与NEC显著相关的因素包括较低的出生体重(p<0.001),胎龄较低(p<0.001),SARS-CoV-2PCR结果阳性(OR=15.333;95%CI=2.074-113.381,p=0.007),窒息(OR=13.143;95%CI=1.411-122.443,p=0.024),和死亡率(OR=156.000;95%CI=13.157-1849.623;p<0.001)。死亡率与较低的胎龄显著相关(p=0.025),剖宫产分娩(p=0.025),窒息(p=0.025)。
UNASSIGNED:SARS-CoV-2阳性母亲出生的新生儿与NEC的重要相关因素包括SARS-CoV-2PCR结果阳性,窒息,较低的胎龄,低出生体重。除了剖腹产,这些因素与新生儿在这种情况下的死亡率有关.
UNASSIGNED: The impact of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic on expectant mother and their babies extends to many aspects of life.
Necrotizing enterocolitis (NEC) has been recognized as a life-threatening gastrointestinal inflammatory process in neonates that has high rates of morbidity and mortality.
UNASSIGNED: To investigate factors associated with NEC in hospitalized neonates whose mothers were SARS-CoV-2-positive and their relationship to mortality.
UNASSIGNED: This observational
study was conducted from May 2020 to March 2021. All neonates who were hospitalized, after confirming that the mother was SARS-CoV-2-positive, were included in this
study. The confirmation of positive SARS-CoV-2 was determined according to the reverse transcription-polymerase chain reaction (PCR) assay. The neonatal SARS-CoV-2 test was performed on the first day of birth. NEC was established based on a suggestive clinical presentation and abnormal abdominal radiographs.
UNASSIGNED: Of the 125 neonates enrolled in this
study, there were 5 neonates who developed NEC and only one survived. Significant associated factors with NEC included lower birth weight (p < 0.001), lower gestational age (p < 0.001), positive SARS-CoV-2 PCR results (OR = 15.333; 95% CI = 2.074-113.381, p = 0.007), asphyxia (OR = 13.143; 95% CI = 1.411-122.443, p = 0.024), and mortality (OR = 156.000; 95% CI = 13.157-1849.623; p < 0.001). Mortality was significantly associated with lower gestational age (p = 0.025), cesarean section delivery (p = 0.025), and asphyxia (p = 0.025).
UNASSIGNED: Significant associated factors with NEC in neonates born to SARS-CoV-2-positive mothers included positive SARS-CoV-2 PCR results, asphyxia, lower gestational age, and lower birth weight. In addition to caesarean section delivery, these factors were related to mortality in neonates in such conditions.