背景:霍奇金淋巴瘤(HL)通过活检明确诊断,治疗是基于阶段。由于疾病的性质,治疗后疗效主要由氟脱氧葡萄糖-正电子发射断层扫描/计算机断层扫描确定,而治疗的疗效未被组织病理学证实。我们报告一例舌癌经HL治疗后,其中一个完全缓解的治疗后淋巴结通过颈部淋巴结清扫术在组织病理学上得到证实。
方法:患者是一名74岁的男性,他的舌头右侧因癌症被转诊到我们医院。他以前曾接受过涉及颈部右侧的HL化疗,并获得了完全缓解。因为他得了cT3N2cM0舌癌,行舌片切除术和双侧颈清扫术。令人惊讶的是,组织病理学检查显示,他的右颈部既没有转移性淋巴结也没有淋巴瘤细胞。此外,他的残余淋巴结没有淋巴结构。
结论:这是一例罕见病例,组织病理学分析证实HL完全缓解。淋巴结结构和淋巴流的缺失导致舌癌对侧颈部淋巴结转移。
Hodgkin lymphoma (HL) is diagnosed definitively by biopsy, and treatment is based on stage. Owing to the nature of the disease, post-treatment efficacy is determined mainly by fluorodeoxyglucose-positron emission tomography/computed tomography, and the efficacy of treatment is not confirmed by histopathology. We report a
case of tongue cancer after treatment for HL, in which a post-treatment lymph node with complete remission was histopathologically confirmed by neck dissection.
The patient was a 74-year-old man who was referred to our hospital for cancer on the right side of his tongue. He had previously undergone chemotherapy for HL involving the right side of his neck and achieved complete remission. Because he had cT3N2cM0 tongue cancer, glossectomy and bilateral neck dissection were performed. Surprisingly, histopathological examination revealed that there was neither metastatic lymph nodes nor lymphoma cells in his right neck. Moreover, there was no lymphatic structure in his remnant lymph nodes.
This was a rare
case in which complete remission of HL was confirmed by histopathological analysis. The absence of lymph node structure and lymphatic flow led to contralateral neck lymph node metastases of tongue cancer.