Nail Diseases

指甲疾病
  • 文章类型: Journal Article
    文献中已经描述了大脚趾远端指骨的骨性生长,但很少。这些甲下骨生长可能是由甲下外生症或甲下骨软骨瘤引起的。这两种异常都是骨生长,软骨帽存在差异,其中外生骨具有纤维软骨,骨软骨瘤有透明软骨。突出的甲下骨外生症和骨软骨瘤存在疼痛症状,发红,和变形的甲床,而不突出的骨软骨瘤只有一个肿块作为表现症状。在这两种情况下,切除病灶并刮治基底有助于防止复发。在骨生长切除结束时需要刮除以避免复发。切除后,应将标本送去进行组织病理学检查,以区分外生骨和骨软骨瘤,在甲岛以下地区被低估了,并排除恶性转化。我们介绍了一个13岁的女孩,她的大脚趾下无突起外生体,并通过切除活检进行了治疗。组织病理学检查证实它是骨软骨瘤,这是少报的。
    Bony outgrowths of the distal phalanx of the great toe have been described in the literature but rarely. These subungual bony outgrowths can be caused by subungual exostosis or subungual osteochondromas. Both of these abnormalities are bony outgrowths with differences in the cartilage cap wherein the exostoses have fibrocartilage, and osteochondromas have hyaline cartilage. The subungual exostosis and osteochondroma that are protruding present symptoms of pain, redness, and deformed nail bed, whereas the nonprotruding osteochondromas have only a lump as the presenting symptom. In both conditions, excision of the lesion and curettage of the base helps prevent a recurrence. Curettage at the end of the excision of the bony outgrowth is required to avoid recurrence. After excision, the specimen should be sent for histopathologic examination to differentiate between the exostosis and osteochondromas, which are underreported in subungual locations, and to rule out malignant transformation. We present a 13-year-old girl with an isolated subungual nonprotruding exostosis of the great toe that was treated by excisional biopsy. The histopathologic examination confirmed it as osteochondroma, which is underreported.
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  • 文章类型: Case Reports
    汗腺细胞瘤是良性的,由汗腺的大汗腺分泌成分引起的囊性肿瘤病变。它们最常见于头部和颈部,倾向于眶周区域。不太频繁的地点包括腋下,乳头,外耳道,包皮,结膜,下唇,和手指,在其他人中。作者报告了一名55岁女性的甲床hiddrocystoma的独特病例,以前没有描述过的网站。
    UNASSIGNED: Apocrine hidrocystomas are benign, cystic neoplastic lesions resulting from the apocrine secretory component of the sweat gland. They most commonly occur on the head and neck, with predilection to the periorbital area. Less frequent sites include the axilla, nipple, external auditory canal, foreskin, conjunctiva, lower lip, and fingers, among others. The authors report a unique case of a nail bed hidrocystoma in a 55-year-old woman, a site not previously described.
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  • 文章类型: Journal Article
    鳞状细胞乳头状瘤是一种良性肿瘤,其发病机理通常与人乳头瘤病毒有关。尽管影响了几个器官,我们没有发现指甲报告的病例。
    一名67岁的女性出现了从2021年开始的右拇指指甲疼痛病变,红斑外观演变为黑色和扩张性生长。由于进化和症状,她选择了切除,鳞状细胞乳头状瘤的组织病理学报告。用咪喹莫特进行补充治疗,良好的愈合和疼痛控制。
    由于缺乏以前的报告,治疗基于位于其他区域的乳头状瘤的治疗选择.进行了切除术,随后应用咪喹莫特,反应良好。预后良好;然而,需要进一步的研究来阐明指甲鳞状细胞乳头状瘤的诊断和治疗。
    UNASSIGNED: Squamous cell papilloma is a benign tumor whose pathogenesis is generally related to the human papillomavirus. Despite affecting several organs, we did not find cases reported in the nails.
    UNASSIGNED: A 67-year-old female presented with a painful lesion in the nail of the right hallux that started in 2021, with an erythematous appearance evolving to black and expansive growth. Due to the evolution and symptoms, she opted for excision, with a histopathological report of squamous cell papilloma. Complementary treatment with imiquimod was performed, with good healing and pain control.
    UNASSIGNED: Due to the lack of previous reports, treatment was based on therapeutic options for papillomas located in other regions. Excision was performed, followed by application of imiquimod with good response. The prognosis is favorable; however, further studies are needed to elucidate the diagnosis and management of nail squamous cell papilloma.
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  • 文章类型: Journal Article
    目的:文献中讨论了小儿黑甲的自然史和活检排除黑色素瘤的必要性。我们假设在接受甲癣甲床活检的小儿患者中,恶性指甲病理学的发生率较低。
    方法:我们在2007年至2022年期间,对一家机构的54例儿童患者(年龄<18岁)进行了回顾性图表回顾,这些患者表现为黑甲癣并接受了甲床活检。收集的数据点包括患者人口统计学,病史,体检结果,病理报告,和临床照片。进行单变量和多变量分析以评估与高风险病理结果相关的危险因素。
    结果:黑甲癣发病的平均年龄为5.5岁(SD4.4)。首次活检的平均年龄为7.8岁(SD4.3)。体检时,27例患者至少有四个与黑色素瘤有关的特征(不对称性,边界不规则,颜色异质性,直径>1/3的指甲,不断变化的颜色,不断演变的直径,哈钦森的标志)。最常见的病理诊断是黑素细胞痣(35%),具有良性特征的非典型表皮内黑素细胞增生(AIMP)(24%),甲下扁豆(22%),和AIMP相关功能(17%)。没有原位黑色素瘤或侵袭性恶性黑色素瘤的病例。关于多元回归,与更多相关病理相关的唯一显著危险因素(具有相关特征的AIMP)是进行活检的日历年(系数=-0.34,P=0.016).体检特征与高危病理之间没有关联。12例患者手术再次切除病灶,其中6例是由于AIMP切除不完全,具有相关特征,其中6例是由于复发。
    结论:我们的病例系列没有发现任何由儿童黑甲癣引起的原位黑色素瘤或恶性黑色素瘤病例。具有相关特征的非典型表皮内黑素细胞增生仅与活检的年份相关。这可能反映了对小儿黑甲癣的认识有所提高,尽管其病理特征令人担忧,但通常是良性的。在小儿黑甲癣中进行指甲基质活检的决定应基于患者父母之间的合作讨论,皮肤科医生,和整形外科医生。
    OBJECTIVE: The natural history of pediatric melanonychia and the necessity of biopsy for ruling out melanoma are debated in the literature. We hypothesize that there is a low rate of malignant nail pathology among pediatric patients undergoing nail bed biopsy for melanonychia.
    METHODS: We performed a retrospective chart review of 54 pediatric patients (age <18 years) at a single institution who presented with melanonychia and underwent nail bed biopsy from 2007 to 2022. Data points collected included patient demographics, medical history, physical exam findings, pathology reports, and clinical photos. Univariate and multivariate analyses were performed to assess for risk factors associated with high-risk pathology findings.
    RESULTS: The average age of melanonychia onset was 5.5 years (SD 4.4). The average age of first biopsy was 7.8 years (SD 4.3). On physical exam, 27 patients had at least four features concerning for melanoma (asymmetry, border irregularity, color heterogeneity, diameter > 1/3 of nail, evolving color, evolving diameter, Hutchinson\'s sign). The most common pathology diagnoses were melanocytic nevus (35%), atypical intraepidermal melanocytic proliferation (AIMP) with benign features (24%), subungual lentigo (22%), and AIMP with concerning features (17%). There were no cases of melanoma in situ or invasive malignant melanoma. On multivariate regression, the only significant risk factor associated with more concerning pathology (AIMP with concerning features) was the calendar year in which biopsy was performed (coefficient = -0.34, P = 0.016). There was no association between physical exam features and high-risk pathology. Twelve patients had surgical re-excision of the lesion, 6 of which were due to incomplete excision of AIMP with concerning features and 6 of which were due to recurrence.
    CONCLUSIONS: Our case series did not find any cases of melanoma in situ or malignant melanoma arising from pediatric melanonychia. Atypical intraepidermal melanocytic proliferation with concerning features was associated only with the year in which the biopsy was performed, which may reflect the improved understanding of pediatric melanonychia as often benign despite concerning features on pathology. The decision to perform a nail matrix biopsy in pediatric melanonychia should be based on a collaborative discussion between the patient\'s parents, dermatologist, and plastic surgeon.
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  • 文章类型: Case Reports
    暂无摘要。
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  • 文章类型: Review
    背景:该病例报告描述了一名38岁女性第二脚趾血管瘤的诊断,其次是手术治疗利用经甲方法来保存指甲。这项研究强调了在保持指甲完整性的同时治疗此类肿瘤的诊断挑战和手术策略。
    方法:疼痛每周发生一次,但随着时间的推移,它增加了,在寻求医疗之前,她每天经历5次以上的疼痛。冷水碰到她的脚趾时疼痛加重了。
    方法:我们观察到轻微的驼峰,表明指甲板畸形,患者在患处表现出严重的触痛(阳性Love测试)。进行彩色双工超声进一步调查,在右第二脚趾的甲床处发现一个大小为0.5厘米的高血管低回声结节。
    方法:手术是在数字神经阻滞麻醉下进行的,使用改良的经甲钉保留方法切除血管球瘤。
    结果:手术前报告的疼痛在术后有所改善,恢复顺利,没有任何其他并发症。
    结论:本文对一种罕见的第二足趾血管球瘤进行了全面检查,阐明诊断复杂性和治疗方式。它强调了实现全肿瘤切除的双重必要性,同时还要考虑美学结果。本文提出的见解旨在为面临类似临床情景的临床医生提供有价值的指导。强调有效的肿瘤管理和保持化妆品完整性之间微妙的相互作用。
    BACKGROUND: This case report describes the diagnosis of a glomus tumor in the second toe of a 38-year-old female, followed by surgical treatment utilizing a transungual approach to preserve the nail. This study highlights the diagnostic challenges and surgical strategies to treat such tumors while preserving nail integrity.
    METHODS: Pain occurred once a week, but over time, it increased, and just before seeking medical attention, she experienced pain more than 5 times a day. The pain worsened when cold water touched her toe.
    METHODS: We observed a slight hump indicating nail plate deformity, and the patient exhibited severe pinpoint tenderness (positive Love test) in the affected area. Color duplex ultrasound was performed for further investigation, revealing a hypervascular hypoechoic nodule measuring 0.5 cm in size at the nail bed of the right second toe.
    METHODS: The surgery was performed under digital nerve block anesthesia using a modified transungual nail-preserving approach for the excision of the glomus tumor.
    RESULTS: The pain that was reported prior to the surgery has improved postoperatively, and the recovery has been uneventful without any other complication.
    CONCLUSIONS: This paper provides a comprehensive examination of a rare glomus tumor in the second toe, elucidating both diagnostic intricacies and treatment modalities. It emphasizes the dual necessity of achieving total tumor excision while also considering aesthetic outcomes. The insights presented herein are intended to serve as valuable guidance for clinicians confronted with similar clinical scenarios, underlining the delicate interplay between effective tumor management and the preservation of cosmetic integrity.
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    文章类型: Review
    BACKGROUND: the glomus tumor is a benign neoplasm originated in the smooth muscle cells of the vascular glomus. Approximately 80% of lesions are located on the upper extremity and, of these, the majority are in the subungual area. The diagnosis must include imaging tests, among which ultrasound stands out, being a good alternative due to its low cost and accessibility.
    OBJECTIVE: we present a case of late diagnosis of surgically managed glomus tumor, as well as a review of the existing literature for diagnosis, treatment, and prognosis of this uncommon pathology.
    METHODS: the case of a 52-year-old female patient who reported chronic, burning pain, radiating to the distal phalanx of the thumb with no history of trauma, of 2 years of evolution and which limited her daily life activities, is presented. The exploration with interphalangeal Doppler ultrasound is complemented, being an excellent alternative due to its easy accessibility. A glomus tumor was diagnosed in the interphalangeal thumb. An \"H\" approach was performed on the interphalangeal fold with subungual dissection with resection of the tumor piece and follow-up by an outpatient clinic where a surgical wound with adequate healing was found. Physical examination with capacity for the mobilization of the distal interphalangeal joint (IFJ) and visual analogue scale (VAS) 1 point. The updated pathological evaluation of the existence of a glomus tumor.
    CONCLUSIONS: ultrasound is an excellent aid in the diagnosis, as well as in the surgical planning for the treatment of the glomus tumor; for being accessible, low cost and highly effective. The anatomopathological study is the gold standard.
    UNASSIGNED: el tumor glómico es una neoplasia benigna originada en las células musculares lisas del glomus vascular. Aproximadamente 80% de las lesiones se localiza en la extremidad superior y, de éstas, la mayoría se sitúa en la zona subungueal. El diagnóstico debe incluir exámenes de imágenes, entre los que destaca la ecografía, siendo una buena alternativa por su bajo costo y accesibilidad.
    OBJECTIVE: presentamos un caso de diagnóstico tardío de tumor glómico manejado quirúrgicamente, así como revisión de la literatura existente para diagnóstico, tratamiento y pronóstico de esta patología poco común.
    UNASSIGNED: paciente femenino de 52 años que refería un dolor crónico, ardoroso, irradiado hacia falange distal del pulgar sin antecedente traumático, de dos años de evolución y que limitaba actividades de su vida diaria. Se complementa exploración con ultrasonido Doppler interfalángico siendo una excelente alternativa por su fácil accesibilidad. Se diagnostica tumor glómico en interfalángica pulgar. Se realiza abordaje en \"H\" sobre pliegue interfalángico con disección subungueal con resección de pieza tumoral y seguimiento por consulta externa donde se encuentra herida quirúrgica con adecuada cicatrización. Exploración física con capacidad para la movilización de movilización de la articulación interfalángica distal (IFD) y escala visual análoga (EVA) de 1 punto. La evaluación anatomopatológica informó la existencia de tumor glómico.
    CONCLUSIONS: la ecografía es una excelente ayuda en el diagnóstico, así como en la planificación operatoria para el tratamiento del tumor glómico, por ser accesible, de bajo costo y de alta efectividad. El estudio anatomopatológico es el estándar de oro que da la certeza diagnóstica.
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  • 文章类型: Case Reports
    甲下脓肿很少见,缺乏通过成像发现的有关它们的信息。二氧化碳激光引流和抗生素是甲下脓肿的有效治疗策略。我们报告了一例47岁的男性医护人员,患有甲下脓肿,仅人工引流后即可改善。超声和磁共振图像显示指甲板和远端指骨之间有肿瘤(有血流)。培养试验显示金黄色葡萄球菌。患者症状迅速缓解,4个月后指甲恢复正常。这可能是关于甲下脓肿的超声和磁共振成像发现的第一份报告。
    Subungual abscesses are rare, and information about them through imaging findings is lacking. Carbon dioxide laser drainage and antibiotics are effective treatment strategies for subungual abscesses. We report a case of a 47-year-old male healthcare worker with a subungual abscess that improved after manual drainage alone. Ultrasound and magnetic resonance images showed a tumor (with blood flow) between the nail plate and distal phalanx. Culture tests revealed Staphylococcus aureus. The patient\'s symptoms resolved quickly and the nail returned to normal after 4 months. This is possibly the first report of a subungual abscess with ultrasound and magnetic resonance imaging findings.
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  • 文章类型: Journal Article
    背景:明确的指甲营养不良,先天性,创伤性,或获得,主要影响老年患者,定期保守治疗可能无法充分管理。确定的手术治疗可以被认为是一种替代方法,尤其是有症状的患者。
    目的:为了评估88%苯酚溶液治疗某些指甲营养不良的全矩阵切除术的有效性,没有以其他方式令人满意地管理。
    方法:对37例患者进行了48例手术。疼痛评估,干扰鞋子和步态,复发,并评估患者对手术的满意度。
    结果:所有患者在手术前都提到了穿鞋时的疼痛或损伤。美容效果显着,大多数患者(95.11%)在手术后的不适感得到了显着改善。随访12个月无严重并发症发生。
    结论:单中心研究和患者数量有限。
    结论:用88%苯酚溶液行全筋膜切除术是一种有效的手术方法,术后并发症发生率低,治疗有症状的指甲营养不良成功率高。对美容效果的满意度很高,对于有相关并发症的患者来说,这是一个安全的程序。
    BACKGROUND: Definitive nail dystrophies, congenital, traumatic, or acquired, affecting mainly elderly patients, may not be sufficiently managed with a periodic conservative treatment. A definitive surgical treatment may be considered an alternative method, especially in symptomatic patients.
    OBJECTIVE: To evaluate the effectiveness of total matricectomy with 88% phenol solution to treat some nail dystrophies, not otherwise satisfactorily managed.
    METHODS: A series of 48 surgeries were performed on 37 patients. Pain evaluation, interference with shoes and gait, recurrences, and patients\' satisfaction with procedure were evaluated.
    RESULTS: All patients mentioned some pain or impairment in wearing shoes before surgery. Cosmetic results were remarkable, and most of the patients (95.11%) had a dramatic improvement of their discomfort after the procedure. No severe complications occurred during the 12-month follow-up.
    CONCLUSIONS: Single-center study and the limited number of patients.
    CONCLUSIONS: Total matricectomy with 88% phenol solution is an effective surgical method with low rates of postoperative morbidity and high success rates for treating symptomatic nail dystrophies. The satisfaction with the cosmetic results is high, and this is a safe procedure for patients with associated comorbidities.
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  • 文章类型: Case Reports
    牙本质瘤是一种罕见的,指甲的纤维上皮肿瘤。虽然是良性的,不必要和过度的治疗,例如广泛或完全去除指甲基质,过去曾报道过。最近,据推测,甲癣起源于甲癣,指甲基质的真皮基质。切除肿瘤的间质而不是上皮成分是重要的。然而,由于正常和患病基质之间的界限通常不清楚,在肿瘤投影的底部进行最小切除就足够了。我们报告了一例甲癣,并提出了一种手术治疗方法,该方法可最大程度地减少指甲板的术后畸形。
    Onychomatricoma is a rare, fibroepithelial tumor of the nail. Although it is benign, unnecessary and excessive treatment, such as extensive or total removal of the nail matrix, has been reported in the past. Recently, it was speculated that onychomatricoma is derived from onychomatricodermis, the dermal stroma of the nail matrix. Excision of the stromal rather than the epithelial component of the tumor is important. However, since the boundary between the normal and diseased stroma is usually unclear, minimal excision at the base of the tumor projection should be sufficient. We report a case of onychomatricoma and suggest a method of surgical treatment that would minimize postoperative deformity of the nail plate.
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