药物引起的肌病是肌肉疼痛的常见原因,引起肌肉副作用的药物范围在不断扩大。在这篇文章中,作者全面讨论了肌痛患者的诊断和治疗过程,并介绍了药物诱发的肌病。该综述提供了有关降血脂药物治疗期间肌病发生率的文献的详细分析,β受体阻滞剂,胺碘酮,秋水仙碱,糖皮质激素,抗疟药,环孢菌素,齐多夫定,和检查点抑制剂,越来越多地用于治疗恶性肿瘤的一组药物。本文考虑了不同类型肌病的临床过程,他们的发病机理,组织病理学特征,以及这些疾病的治疗方法。本文的目的是从最新的可用文献中收集有关课程的最新信息,病理生理学,和药物诱导的肌病的治疗选择,系统化药物诱导肌病的知识,并提请内科医生注意这些临床问题是一个重要的治疗问题。
Drug-induced myopathies are a common cause of muscle pain, and the range of drugs that can cause muscle side effects is constantly expanding. In this article, the authors comprehensively discuss the diagnostic and therapeutic process in patients with myalgia, and present the spectrum of drug-induced myopathies. The
review provides a detailed analysis of the literature on the incidence of myopathy during treatment with hypolipemic drugs, beta-blockers, amiodarone, colchicine, glucocorticosteroids, antimalarials, cyclosporine, zidovudine, and checkpoint inhibitors, a group of drugs increasingly used in the treatment of malignancies. The article considers the clinical course of the different types of myopathies, their pathogenesis, histopathological features, and treatment methods of these disorders. The aim of this paper is to gather from the latest available literature up-to-date information on the course, pathophysiology, and therapeutic options of drug-induced myopathies, to systematize the knowledge of drug-induced myopathies and to draw the attention of internists to the fact that these clinical issues are an important therapeutic problem.