■肺炎支原体肺炎(MPP)和肺炎链球菌肺炎(SPP)是呼吸道感染的常见原因,本研究的目的是探讨MPP患儿和SPP患儿临床特征的差异.
这项回顾性研究包括2015年1月至2020年1月在5年内被诊断为MPP或SPP的入院儿童。在临床特征方面,将MPP儿童与SPP儿童进行了比较。
■506例MPP患者与311例SPP患者的临床差异进行了比较。MPP组的中位年龄为60[29-89]个月,SPP组的中位年龄为24[10-40]个月。MPP患者年龄较大,入院前接受抗生素治疗的发生率较高,发烧,干咳,多呼吸和腹泻患者均优于SPP(均p<0.01)。SPP患者更容易出现喘息,发紫和易怒(均p<0.01)。我们研究的实验室发现,MPP和SPP患者的平均白细胞计数存在显着差异,中性粒细胞%(N%),淋巴细胞百分比(L%),ALT水平,AST水平,LDH水平和加速降钙素原(PCT)的发生率(均p<0.01)。年龄较低,没有干咳,没有呼吸困难,较低的LDH水平,较高的PCT可能导致SPP的诊断。我们的研究表明,年龄预测MPP的准确性高于LDH水平,年龄>48.5个月被证明是早期评估和识别MPP的独立预测因素。
■总而言之,MPP和SPP患者通常表现为发热,咳嗽和一些非特异性症状。我们的研究表明,年龄,干咳,呼吸息肉,LDH水平,PCT水平是与MPP和SPP相关的独立预测因素。
UNASSIGNED: Mycoplasma pneumoniae pneumonia (MPP) and Streptococcus pneumoniae pneumonia (SPP) are frequent causes of respiratory tract infection, the aims of the study were to explore the differences in clinical features between children with MPP and those with SPP.
UNASSIGNED: This retrospective study included admitted children who were diagnosed with MPP or SPP over 5 years from January 2015 to January 2020. Children with MPP were compared to children with SPP in terms of clinical features.
UNASSIGNED: 506 patients with MPP were compared to 311 patients with SPP in terms of clinical differences. The MPP group with a median age of 60 [29-89] months and the SPP group with a median age of 24 [10-40] months. Patients with MPP were older and had a higher occurrence of receiving antibiotics before admission, fever, dry cough, polypnea and diarrhea than patients with SPP (all p < 0.01). Patients with SPP were more likely to have wheezing, cyanosis and irritability (all p < 0.01). Laboratory findings in our study showed that there were significant differences between MPP and SPP patients in mean leucocyte count, neutrophil % (N%), lymphocyte % (L%), ALT levels, AST levels, LDH levels and incidence of accelerated procalcitonin (PCT) (all p < 0.01). Lower age, no dry cough, no polypnea, lower LDH levels, and higher PCT might lead to the diagnosis of SPP. Our study showed that age had a higher accuracy in predicting MPP than LDH levels, with an age >48.5 months shown to be an independent predictive factor for the early evaluation and identification of MPP.
UNASSIGNED: In conclusion, patients with MPP and SPP usually present with fever, cough and some nonspecific symptoms. Our study showed that age, dry cough, polypnea, LDH levels, and PCT levels were independent predictive factors associated with MPP and SPP.