Mural thrombus

  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    背景:形态学上,主动脉瘤破裂的风险主要根据其类型进行评估(例如,梭形或囊状)和直径。基于有限元分析,近年来,峰值壁应力已被确定为更敏感,更具体的预测破裂。此外,在有限分析中,动脉瘤的颈部是壁应力的最高峰值,并与破裂点有关。
    方法:一名74岁有红细胞增多症病史的男性患者在术前检查慢性脓胸时偶然发现了一个囊状主动脉瘤(84mm)。使用开放式支架进行主动脉弓移植物置换。
    结论:形态学,这种情况与破裂的风险很高有关;尽管如此,它没有破裂。在这种情况下,动脉瘤颈部有一个壁血栓(可能是由于红细胞增多症形成的),该血栓正在经历最高的壁应力峰值,并与破裂点相关.即使对于巨大的囊状动脉瘤,壁血栓也可以降低壁应力峰值,并可以降低破裂的风险。此外,动脉瘤中的壁血栓被完全占据,例如在线圈栓塞期间。因此,红细胞增多症可以降低巨大囊状动脉瘤破裂的风险。
    BACKGROUND: Morphologically, the risk of aortic aneurysm rupture is mainly evaluated based on its type (e.g., fusiform or saccular) and diameter. Based on the finite element analysis, peak wall stress has been identified as a more sensitive and specific predictor of rupture in recent years. Moreover, in finite analysis, the neck of aneurysm is the highest peak wall stress and is associated with the rupture point.
    METHODS: A saccular aortic aneurysm (84 mm) was incidentally detected during preoperative examination for chronic empyema in a 74-year-old male patient with a history of polycythemia. Aortic arch graft replacement using an open stent was performed.
    CONCLUSIONS: Morphologically, this case was associated with a very high risk of rupture; nevertheless, it did not rupture. In this case, a mural thrombus (likely formed due to polycythemia) covered the neck of aneurysm that is experiencing the highest peak wall stress and is associated with the rupture point. The mural thrombus decreased peak wall stress and could reduce the risk of rupture even for huge saccular aneurysms. Furthermore, the mural thrombus was fully occupied in aneurysms, such as during coil embolization. Thus, polycythemia could decrease the risk of rupture of huge saccular aneurysms.
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  • 文章类型: Case Reports
    心肌梗死(MI)可导致广泛的机械性并发症。左心室假性动脉瘤(LVP)是MI的罕见但严重的并发症。
    一名69岁女性,既往有冠状动脉旁路移植术,并有下外侧ST段抬高型心肌梗死(STEMI)病史,但未能对左回旋支动脉进行血运重建,并在STEMI后2年出现坏疽的右脚趾。右下肢的计算机断层扫描血管造影显示动脉闭塞和轻度动脉粥样硬化疾病。超声心动图显示假性动脉瘤,附壁血栓是急性肢体缺血的根本原因。患者开始接受肝素治疗,并咨询了心胸外科手术,但没有手术,因为手术的风险大于获益。在医院第3天,由于组织无法存活,患者接受了坏疽脚趾的截肢手术。患者在住院期间保持稳定,并在第5天接受长期抗凝治疗后出院。
    LVPs具有广泛的演示文稿,从无症状或非特异性症状到终末器官损伤的血栓栓塞,就像我们的情况一样。因此,早期诊断和治疗至关重要.我们的患者先前的冠状动脉旁路移植术很可能有助于形成纤维性心包,从而密封假性动脉瘤并防止其破裂。
    STEMI需要密切跟进,尤其是在无法实现血运重建的情况下,由于机械性并发症和死亡率的风险很高。医师应高度怀疑既往MI患者的LVP,鉴于其广泛的演讲。
    Myocardial infarction (MI) can lead to a wide spectrum of mechanical complications. Left ventricular pseudoaneurysm (LVP) is a rare but serious complication of MI.
    UNASSIGNED: A 69-year-old woman with prior coronary artery bypass grafting and a remote history of inferolateral ST-elevation MI (STEMI) with failure to revascularize the left circumflex artery presented with gangrenous right toes that appeared 2 years after her STEMI. A computed tomography angiogram of the right lower extremity showed arterial occlusion and mild atherosclerotic disease. Echocardiography revealed a pseudoaneurysm with an adherent mural thrombus as the underlying cause of acute limb ischemia. The patient was started on heparin and cardiothoracic surgery was consulted but did not operate as the risk of surgery outweighed the benefit. On hospital day 3, the patient underwent amputation of her gangrenous toes as the tissue was nonviable. The patient remained stable during her hospital stay and was discharged on day 5 on long-term anticoagulation.
    UNASSIGNED: LVPs have a wide spectrum of presentations, from asymptomatic or nonspecific symptoms to thromboembolism with end-organ damage, such as in our case. Therefore, early diagnosis and management are of paramount importance. Our patient\'s prior coronary artery bypass grafting most likely helped in forming a fibrous pericardium that sealed the pseudoaneurysm and prevented its rupture.
    UNASSIGNED: STEMI requires close follow-up, especially in cases where revascularization is not achievable, as the risk of mechanical complications and mortality is high. Physicians should have a high suspicion for LVP in patients with prior MI, given its wide spectrum of presentations.
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  • 文章类型: Case Reports
    主动脉弓血栓是一种罕见的实体,可导致灾难性的后遗症。这是一例65岁女性患者的病例报告,该患者在到达急诊科前一天出现胸痛。排除了急性冠脉综合征(ACS)和肺栓塞(PE)。经食管超声心动图(TEE)证实,在胸部计算机断层扫描血管造影(CTA)上明显的主动脉弓远端充盈缺损是漂浮的主动脉弓远端血栓。没有潜在动脉瘤的证据,解剖,或显著的动脉粥样硬化。该患者被认为是手术干预的高风险,因此,我们决定让患者开始接受直接口服抗凝药(DOACs)的慢性抗凝治疗.三个月后的CTA随访显示血栓完全消退。该报告强调了这种危险的病理,并概述了诱发因素,放射学发现,以及浮动式主动脉弓血栓的管理策略。
    Aortic arch thrombus is a rare entity that can result in catastrophic sequelae. This is a case report of a 65-year-old female patient who presented with chest pain that started one day prior to arrival at the emergency department. Acute coronary syndrome (ACS) and pulmonary embolism (PE) were ruled out. A filling defect at the distal aortic arch evident on chest computed tomography angiography (CTA) was confirmed to be a floating distal aortic arch thrombus on transesophageal echocardiogram (TEE). There was no evidence of an underlying aneurysm, dissection, or significant atherosclerosis. The patient was considered to be at high risk for surgical intervention, hence, a decision was made to start the patient on chronic anticoagulation with direct oral anticoagulants (DOACs). A follow-up CTA three months later showed total resolution of the thrombus. The report highlights this treacherous pathology and provides an overview of the predisposing factors, radiologic findings, as well as management strategies for floating aortic arch thrombi.
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  • 文章类型: Case Reports
    Left ventricular mural thrombus (LVMT) is a life-threatening complication in patients with left ventricular dysfunction.
    A 67-year-old man had a history of penetrating myocardial infarction and left ventricular aneurysm (LVA). The patient was scheduled for a non-cardiac surgery and stopped aspirin for 10 days to reduce the risk of bleeding. Fresh LVMT was revealed via the transesophageal echocardiography (TEE) after the preoperative discontinuation of aspirin.
    Perioperative repeated evaluation for the thrombosis by echocardiography is essential in cases of patients with cardiovascular disease undergoing non-cardiac surgery. In high risk patient, during temporary interruption of antiplatelets, bridging with perioperative low-molecular-weight heparin is advisable.
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  • 文章类型: Journal Article
    Abdominal aortic aneurysm (AAA) may present with subtle clinical findings. Recognition of the imaging features of an impending rupture is key for timely diagnosis. This report reviews the classic computed tomography findings of impending AAA rupture and presents a recent case which illustrates the key features.
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