Carbohydrates are one of the three macronutrients that provides energy in diets and are classified by their structures. Starch is a nonstructural carbohydrate and polysaccharide made of glucose monomers used for storage in plant cells. When starch makes up greater than 30% of the DM in diets there can be adverse effects on NDF digestibility due to decreases in ruminal pH. Sugars are water soluble carbohydrates that consist of monosaccharide and disaccharide units. Sugars ferment faster than starch because microorganisms in the rumen can ferment carbohydrates at different rates depending on their structure; however, this has not been shown to have negative effects on the ruminal pH. Sources of sugars such as molasses (sucrose) or whey (lactose) can be included in the diet as a partial replacement for starch in dairy cow diets. The purpose of replacing starch with sugars in a diet would be to add differing sources of carbohydrates in the diet to allow for continual fermentation of carbohydrates by the microorganisms in the rumen. It has been seen in studies and previous literature that the partial replacement of starch with sugars has the potential to maintain the ruminal environment and milk yield and composition in dairy cows without reducing NDF digestibility. The objective of this review is to evaluate the effects of partially replacing starch with sugars in dairy diets and its implication on ruminal fermentation, nutrient utilization, milk production, and feeding replacement strategy.

Aconitic acid (propene-1,2,3-tricarboxylic acid) is the most prevalent 6-carbon organic acid that accumulates in sugarcane and sweet sorghum. As a top value-added chemical, aconitic acid may function as a chemical precursor or intermediate for high-value downstream industrial and biological applications. These downstream applications include use as a bio-based plasticizer, cross-linker, and the formation of valuable and multi-functional polyesters that have also been used in tissue engineering. Aconitic acid also plays various biological roles within cells as an intermediate in the tricarboxylic acid cycle and in conferring unique survival advantages to some plants as an antifeedant, antifungal, and means of storing fixed pools of carbon. Aconitic acid has also been reported as a fermentation inhibitor, anti-inflammatory, and a potential nematicide. Since aconitic acid can be sustainably sourced from renewable, inexpensive sources such as sugarcane, molasses, and sweet sorghum syrup, there is enormous potential to provide multiple streams of additional income to the sugar industry through downstream industrial and biological applications that we discuss in this review.

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: Background: Constipation in hospitalized patients is common. As a treatment of last resort for unresolved constipation, a milk and molasses enema is often used by nursing staff. But there has been little research investigating the safety and efficacy of this approach.
OBJECTIVE: The purpose of this retrospective study was to evaluate the safety of milk and molasses enemas for hospitalized adults with constipation that remained unresolved after standard treatment options were exhausted.
METHODS: Data were extracted from the electronic health records (EHRs) of 615 adult patients who had received a milk and molasses enema between July 2009 and July 2013 at a large midwestern academic medical center. Data analysis occurred for a random subset of this group.Participant characteristic variables included age, sex, admitting diagnosis, diet orders, medications, laxatives and enemas administered before the milk and molasses enema, and laboratory values. Serious complication variables included bacteremia, bowel perforation, electrolyte abnormalities, allergic reaction, abdominal compartment syndrome, cardiac arrhythmia, dehydration, and death.
RESULTS: The final sample of 196 adults had a mean age of 56 years; 61.2% were female and 38.8% were male. Of 105 admitting diagnoses, the most frequent (9.7%) was abdominal pain, unspecified site. Of the 14 discharge dispositions, the most frequent was home or self-care (50.5%). A laxative order was present for 97.4% of patients and a stool softener order was present for 86.2%. Sodium and potassium levels remained within normal limits during hospitalization. For the subset of patients who had these values measured within 48 hours before and after milk and molasses enema administration, no significant changes were found. No cases of nontraumatic abdominal compartment syndrome or other serious adverse enema-related events were documented in the EHR.
CONCLUSIONS: No safety concerns were identified from this retrospective EHR review of hospitalized adults who received a milk and molasses enema for constipation relief. The findings indicate that this treatment is safe, although further study examining its efficacy in this population is needed.

Distillery effluent is a contaminated stream with high chemical oxygen demand (COD) varying from 45,000 to 75,000 mg/l and low pH values of between 4.3 and 5.3. Different processes covering aerobic, anaerobic as well as physico-chemical methods which have been employed to this effluent has been given in this review paper. Among the different methods available, it was found that \"An Inverse Anaerobic Fluidization\" to be a better choice for treating effluent from molasses-based distillery industries using an inverse anaerobic fluidized-bed reactor (IAFBR). This technology has been widely applied as an effective step in removing 80-85% of the COD in the effluent stream. Therefore, in this review, attention has been paid to highlight in respect of fluidization phenomena, process performance, stability of the system, operating parameters, configuration of inverse anaerobic fluidization and suitable carrier material employed in an inverse anaerobic fluidized-bed reactor especially for treating this effluent.

Molasses-based distilleries are one of the most polluting industries generating large volumes of high strength wastewater. Different processes covering anaerobic, aerobic as well as physico-chemical methods have been employed to treat this effluent. Anaerobic treatment is the most attractive primary treatment due to over 80% BOD removal combined with energy recovery in the form of biogas. Further treatment to reduce residual organic load and color includes various: (i) biological methods employing different fungi, bacteria and algae, and (ii) physico-chemical methods such as adsorption, coagulation/precipitation, oxidation and membrane filtration. This work presents a review of the existing status and advances in biological and physico-chemical methods applied to the treatment of molasses-based distillery wastewater. Both laboratory and pilot/industrial studies have been considered. Furthermore, limitations in the existing processes have been summarized and potential areas for further investigations have been discussed.

Effluent originating from distilleries known as spent wash leads to extensive soil and water pollution. Elimination of pollutants and colour from distillery effluent is becoming increasingly important from environmental and aesthetic point of view. Stillage, fermenter and condenser cooling water and fermenter wastewater are the primary polluting streams of a typical distillery. Due to the large volumes of effluent and presence of certain recalcitrant compounds, the treatment of this stream is rather challenging by conventional methods. Therefore, to supplement the existing treatments, a number of studies encompassing physico-chemical and biological treatments have been conducted. This review presents an account of the problem and the description of colour causing components in distillery wastewater and a detailed review of existing biological approaches. Further, the studies dealing with pure cultures such as bacterial, fungal, algal and plant based systems have also been incorporated. Also, the roles of microbial enzymes in the decolourization process have been discussed to develop a better understanding of the phenomenon.

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