Mirizzi syndrome

Mirizzi 综合征
  • 文章类型: Case Reports
    Mirizzi综合征,胆石症的罕见并发症,涉及胆结石导致肝总管受压。它带来了非特异性症状的诊断挑战。早期识别和手术干预至关重要,强调多学科的方法,这种复杂的条件与潜在的并发症。
    方法:一名69岁女性出现瘙痒,黄疸,还有肝绞痛病史.实验室结果显示无炎症迹象,但提示胆汁淤积。影像学提示Mirizzi综合征1型,经MRI证实。病人接受了手术,显示II型Mirizzi综合征,存在胆囊胆总管瘘,占不到主胆管周长的三分之一。进行了胆囊大部切除术和将主胆管缝合到T形管上,导致10天后血液检查的良好恢复和正常化。
    Mirizzi综合征,以外科医生PabloLuisMirizzi的名字命名,在1948年首次详细介绍。临床症状包括黄疸,绞痛,以及胆囊胆总管瘘和胆石性肠梗阻等并发症。血液检查和成像辅助诊断。手术治疗的目标是缓解梗阻和修复缺损。解剖卡洛的三角形有风险。在复杂的情况下,可以考虑胆囊-胆总管-十二指肠造口术。
    结论:Mirizzi综合征,一种罕见但意义重大的疾病,需要仔细的临床注意,以防止诊断不足。及时和适当的管理,与ERCP一起使用成像测试,对于最佳结果和并发症预防至关重要。
    UNASSIGNED: Mirizzi syndrome, a rare complication of cholelithiasis, involves gallstones causing common hepatic duct compression. It poses diagnostic challenges with nonspecific symptoms. Early recognition and surgical intervention are crucial, emphasizing a multidisciplinary approach for this complex condition with potential complications.
    METHODS: A 69-year-old woman presented with pruritus, jaundice, and a history of hepatic colics. Laboratory results showed no signs of inflammation but indicated cholestasis. Imaging suggested Mirizzi syndrome type 1, confirmed by MRI. The patient underwent surgery, revealing Mirizzi syndrome type II with the presence of a cholecystocholedochal fistula involving less than one-third of the circumference of the main bile duct. Subtotal cholecystectomy and suturing of the main bile duct onto a T-tube were performed, resulting in a favorable recovery and normalization of blood tests after 10 days.
    UNASSIGNED: Mirizzi syndrome, named after surgeon Pablo Luis Mirizzi, was first detailed in 1948. Clinical symptoms include jaundice, colic pain, and complications such as cholecystocholedochal fistula and gallstone ileus. Blood tests and imaging aid diagnosis. Surgical management targets obstruction relief and defect repair. Dissecting Calot\'s triangle carries risks. In complex cases, cholecysto-choledocus-duodenostomy may be considered.
    CONCLUSIONS: Mirizzi syndrome, a rare but significant condition, demands careful clinical attention to prevent underdiagnosis. Timely and appropriate management, utilizing imaging tests alongside ERCP, is essential for optimal outcomes and complication prevention.
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  • 文章类型: Journal Article
    胆结石相关疾病包括由胆道结石形成引起的一系列疾病,导致梗阻和炎症并发症。这些可以显著影响患者的生活质量,并且如果不准确检测,则具有高发病率。适当的影像学检查对于评估胆结石疾病的程度和确保适当的临床治疗至关重要。磁共振成像(MRI)技术(包括磁共振胰胆管造影(MRCP)越来越多地用于诊断胆结石及其并发症,并提供高对比分辨率,并有助于对胆结石疾病过程进行组织水平评估。在这篇综述中,我们试图深入研究MR成像在诊断胆囊内胆结石相关疾病以及与胆结石向胆囊颈或胆囊管迁移相关的并发症中的应用。肝总管或胆管(胆总管结石)及以上,包括胆结石性胰腺炎,胆结石性肠梗阻,Bouveret综合征,掉了胆结石,通过提供我们实践中的关键例子。此外,我们将特别强调MRI和MRCP在提高胆结石相关疾病的诊断准确性和改善患者预后方面的关键作用,并展示各种胆结石相关并发症的相关手术病理标本.
    Gallstone-related disease comprises a spectrum of conditions resulting from biliary stone formation, leading to obstruction and inflammatory complications. These can significantly impact patient quality of life and carry high morbidity if not accurately detected. Appropriate imaging is essential for evaluating the extent of gallstone disease and assuring appropriate clinical management. Magnetic Resonance Imaging (MRI) techniques (including Magnetic Resonance Cholangiopancreatography (MRCP) are increasingly used for diagnosis of gallstone disease and its complications and provide high contrast resolution and facilitate tissue-level assessment of gallstone disease processes. In this review we seek to delve deep into the spectrum of MR imaging in diagnose of gallstone-related disease within the gallbladder and complications related to migration of the gallstones to the gall bladder neck or cystic duct, common hepatic duct or bile duct (choledocholithiasis) and beyond, including gallstone pancreatitis, gallstone ileus, Bouveret syndrome, and dropped gallstones, by offering key examples from our practice. Furthermore, we will specifically highlight the crucial role of MRI and MRCP for enhancing diagnostic accuracy and improving patient outcomes in gallstone-related disease and showcase relevant surgical pathology specimens of various gallstone related complications.
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  • 文章类型: Case Reports
    未经证实:Mirizzi综合征是一种梗阻性黄疸,由埋设在胆囊管内的结石对胆总管造成外源性压迫[1]。胆管炎是一种诊断和治疗紧急情况,其主要风险是感染性休克[1]。它也可以发展为“Ictero-Uremisionic血管结肠炎”,有时伴有极其严重的肾功能衰竭[2]。
    UNASSIGNED:我们报道了一例因严重胆管炎而入院的73岁患者,因感染性休克进入急诊室。鉴于存在急性高热性胆管炎,一方面是脓毒性休克,另一方面是急性肾功能衰竭,诊断为ictero-尿素性血管结肠炎。
    未经证实:血管结肠炎是一种胆管的炎症和感染,其病因是多种多样的,其中:Mirizzi综合征[1]。Mirizzi综合征的解剖学基础通常归因于胆囊管和肝总管之间的异常关系[3]。血管结肠炎构成诊断和治疗紧急情况,其并发症威胁着重要的预后[4]。以败血症成分为主的子宫尿素性血管结肠炎代表了败血症的真实情况,胆汁淤积性黄疸,少尿伴肾功能衰竭[2]。
    未经批准:幸运的是,但总是让人害怕,ictero-尿素性血管结肠炎产生典型的血管结肠炎图像,伴随着严重的感染性休克,在很短的时间内很大程度上与器质性肾功能不全有关[2],70岁以上是一个严重的因素,它构成了治疗紧急情况,需要解除主胆管的阻塞,并可能求助于血液透析[4]。
    UNASSIGNED: Mirizzi syndrome is an obstructive jaundice caused by extrinsic compression of the common bile duct by a stone embedded in the cystic duct [1].Cholangitis is a diagnostic and therapeutic emergency whose main risk is that of septic shock [1]. It can also progress to \"Ictero-Uremigenic Angiocholitis\" associated with sometimes extremely serious renal failure [2].
    UNASSIGNED: We reported the case of a 73-year-old patient admitted to the emergency room with septic shock on severe cholangitis. Given the presence of acute febrile cholangitis with criteria of septic shock on the one hand and acute renal failure on the other hand, the diagnosis of ictero-uremigenic Angiocholitis was made.
    UNASSIGNED: Angiocholitis is an inflammation and infection of the bile ducts, the etiologies of which are diverse, among them: Mirizzi\'s syndrome [1].The anatomical basis of Mirizzi syndrome has generally been attributed to an abnormal relationship between the cystic duct and the common hepatic duct [3]. Angiocholitis constitutes a diagnostic and therapeutic emergency, its complications threaten the vital prognosis [4]. Ictero-uremigenic Angiocholitis where the septic component dominates represents a real picture of sepsis, cholestatic jaundice, oliguria with renal failure [2].
    UNASSIGNED: fortunately rare, but always to be feared, the ictero-uremigenic Angiocholitis produces a typical picture of Angiocholitis, accompanied by a serious septic shock which passes largely to the fore associating in a very short period of time an organic renal insufficiency [2], the Age over 70 is a serious factor, it constitutes a therapeutic emergency requiring desobstruction of the main bile duct and possibly recourse to hemodialysis [4].
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  • 文章类型: Journal Article
    Mirizzi综合征是慢性结石性胆囊炎的罕见并发症。由于缺乏病理体征和症状以及影像学检查的敏感性低,术前诊断具有挑战性。历史上,开腹手术已成为外科治疗的首选.内窥镜和腹腔镜方法已被越来越多地描述为MirizziI型和II型的诊断和治疗选择。但有关更复杂病例管理的数据有限。我们描述了用于治疗IV型Mirizzi综合征的分阶段内窥镜和腹腔镜方法,并回顾了治疗方案。
    Mirizzi syndrome is a rare complication of chronic calculous cholecystitis. Preoperative diagnosis is challenging due to the absence of pathognomonic signs and symptoms and low sensitivity rates of imaging tests. Historically, laparotomy has been the preferred choice of surgical management. Endoscopic and laparoscopic approaches have been increasingly described as diagnostic and therapeutic options for Mirizzi type I and II, but data is limited regarding the management of more complex cases. We describe a staged endoscopic and laparoscopic approach for the management of type IV Mirizzi syndrome and review the management options.
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  • 文章类型: Case Reports
    Mirizzi综合征(MS)是慢性胆结石的罕见并发症。Mirizzi综合征的特征是一组由共同肝或胆总管(CBD)阻塞引起的症状。这可能是由于慢性胆结石性胆囊炎继发的炎症变化所致,胆囊颈或胆囊管受结石的外在压迫。我们介绍了一例86岁的慢性胆结石患者,表现为腹痛和黄疸。经内镜逆行胰胆管造影术(ERCP)后,患者被诊断为MSV型。清除了CBD石头碎片/碎片,患者接受胆囊十二指肠瘘修复手术治疗。MS必须在老年慢性胆结石性胆囊炎伴梗阻性黄疸的鉴别诊断中。需要多种诊断和治疗方法来诊断和管理不同类型的MS。我们的目标是提出这个案例,以突出和提高人们对MS的认识,尤其是慢性胆结石患者。
    Mirizzi syndrome (MS) is a rare complication of chronic gallstones. Mirizzi syndrome is characterized by a set of symptoms that results from obstruction of the common hepatic or common bile duct (CBD). This may be due to extrinsic compression from an impacted gallstone in the gallbladder neck or cystic duct because of inflammatory changes secondary to chronic gallstone cholecystitis. We present a case of an 86-year-old patient with chronic gallstones who presented with abdominal pain and jaundice. The patient was diagnosed with MS type V after endoscopic retrograde cholangiopancreatography (ERCP). CBD stone fragments/debris were removed, and the patient was referred for surgical intervention for the repair of cholecystoduodenal fistula. MS must be in the differential diagnosis in elderly patients with chronic gallstone cholecystitis presenting with obstructive jaundice. Multiple diagnostic and therapeutic approaches are required to diagnose and manage the different types of MS. We aim to present the case to highlight and raise awareness of MS, particularly in patients with chronic gallstones.
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  • 一名76岁男子出现肝功能障碍和肝内胆管扩张。影像学研究显示,两个大石头已经在肝总导管中受到影响,与胆囊融合。患者被诊断为IV型Mirizzi综合征。由于累及右肝动脉的胆囊粘连,肝空肠吻合术和结石清除失败。胆汁流量暂时恢复;然而,16个月后,患者出现胆管炎。通过经口单人胆道镜(SOC)引导的电动液压碎石术取出结石。这是第一个在Mirizzi综合征IV型患者中通过SOC指导治疗完全清除结石的病例。
    A 76-year-old man presented with liver dysfunction and intrahepatic bile duct dilatation. Imaging studies showed two large stones that had become impacted in the common hepatic duct, which was fused with the gallbladder. The patient was diagnosed with Mirizzi syndrome type IV. Hepaticojejunostomy and stone removal failed due to dense gallbladder adhesions involving the right hepatic artery. The bile flow was temporarily restored; however, the patient experienced cholangitis 16 months later. The stones were extracted via peroral single-operator cholangioscopy (SOC)-guided electrohydraulic lithotripsy. This is the first case in which stones were completely removed by SOC-guided treatment in a patient with Mirizzi syndrome type IV.
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  • 文章类型: Journal Article
    背景:Mirizzi综合征(MS)是一种罕见的病理,这对外科医生来说是一个挑战。在手术管理中,由于解剖结构的差异,开放方法与腹腔镜是一个讨论的话题。这项研究的目的是分析我们在Va型腹腔镜治疗这种疾病的经验。
    方法:我们对2014年至2019年在波哥大两个高容量中心诊断为Va型MS并接受腹腔镜治疗的患者进行了描述性回顾性研究。哥伦比亚。
    结果:对1073例胆结石并发症患者进行了评估,其中16例诊断为Va型MS。75%为女性,25%为男性;80%出现黄疸和90%的腹痛;12例患者出现胆囊十二指肠瘘和4例胆囊结肠瘘。所有患者均接受腹腔镜治疗,100%的患者可以进行全胆囊切除术和一期闭合瘘管切除术.转化率为0%。随访18个月。
    结论:腹腔镜治疗MS是可行和安全的;手术组的经验和患者的选择是成功结局的关键。
    BACKGROUND: Mirizzi\'s Syndrome (MS) is a rare pathology, known to be a challenge for the surgeon. In the surgical management, open approach vs laparoscopic is a topic of discussion due to anatomic variations. The aim of this study is to analyze our experience in the laparoscopic management of this condition in Type Va.
    METHODS: We made a descriptive retrospective study of patients diagnosed with MS type Va and treated by laparoscopic approach from 2014 to 2019, in two high volume centers of Bogotá, Colombia.
    RESULTS: 1073 patients who presented complications from gallstones were evaluated, of which 16 were diagnosed with MS type Va. 75% were females and 25% males; 80% presented jaundice and 90% abdominal pain; 12 patients showed cholecystoduodenal fistula and 4 cholecystocolic fistula. All patients underwent laparoscopic management, total cholecystectomy and fistula resection with primary closure was possible on a 100% of the patients. Conversion rate was 0%. The follow up was 18 months.
    CONCLUSIONS: Laparoscopic management of MS is feasible and safe; the experience of the surgery group and selection of the patients is the key to a successful outcome.
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  • 文章类型: Journal Article
    背景:Mirizzi综合征(MS)是一种罕见的病理,这对外科医生来说是一个挑战。在手术管理中,由于解剖结构的差异,开放方法与腹腔镜是一个讨论的话题。这项研究的目的是分析我们在Va型腹腔镜治疗这种疾病的经验。
    方法:我们对2014年至2019年在波哥大两个高容量中心诊断为Va型MS并接受腹腔镜治疗的患者进行了描述性回顾性研究。哥伦比亚。
    结果:对1073例胆结石并发症患者进行了评估,其中16例诊断为Va型MS。75%为女性,25%为男性;80%出现黄疸和90%的腹痛;12例患者出现胆囊十二指肠瘘和4例胆囊结肠瘘。所有患者均接受腹腔镜治疗,100%的患者可以进行全胆囊切除术和一期闭合瘘管切除术.转化率为0%。随访18个月。
    结论:腹腔镜治疗MS是可行和安全的;手术组的经验和患者的选择是成功结局的关键。
    BACKGROUND: Mirizzi\'s Syndrome (MS) is a rare pathology, known to be a challenge for the surgeon. In the surgical management, open approach vs laparoscopic is a topic of discussion due to anatomic variations. The aim of this study is to analyze our experience in the laparoscopic management of this condition in Type Va.
    METHODS: We made a descriptive retrospective study of patients diagnosed with MS type Va and treated by laparoscopic approach from 2014 to 2019, in two high volume centers of Bogotá, Colombia.
    RESULTS: 1073 patients who presented complications from gallstones were evaluated, of which 16 were diagnosed with MS type Va. 75% were females and 25% males; 80% presented jaundice and 90% abdominal pain; 12 patients showed cholecystoduodenal fistula and 4 cholecystocolic fistula. All patients underwent laparoscopic management, total cholecystectomy and fistula resection with primary closure was possible on a 100% of the patients. Conversion rate was 0%. The follow up was 18 months.
    CONCLUSIONS: Laparoscopic management of MS is feasible and safe; the experience of the surgery group and selection of the patients is the key to a successful outcome.
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  • 文章类型: Journal Article
    Laparoscopic approaches for the management of Mirizzi syndrome (MS) are controversial and challenging procedures for high conversion rate. This review aims at evaluating their safety and feasibility.
    We reviewed studies related to the laparoscopic approaches for the management of MS with detailed data of articles from January 2009 to December 2019 found in PubMed.
    From 63 articles, we reviewed 17 articles detailing laparoscopic approaches for MS. There were 857 patients with MS; 432 of which were identified from 73,842 patients underwent cholecystectomy. Laparoscopic approaches were attempted in 440 patients and were successful in 290. The conversion rate was 34.09%. Various methods including laparoscopic cholecystectomy, laparoscopic subtotal cholecystectomy, laparoscopic common bile duct exploration (LCBDE) and (LTCBDE) were performed. The preoperative diagnosis of MS was made in 338 of 500 patients (67.60%). The mean operating time ranged from 49.7 ± 27.5 min to 270.5 ± 65.5 min, and the mean intraoperative bleeding varied from 21.1 ± 15.9 ml to 162.81 ± 40.83 ml. The mean hospital stay varied from 4.5 ± 3.7 to 7.21 ± 1.61 days. Postoperative complications occurred in 27 patients.
    Various laparoscopic approaches are safe and feasible for the treatment of MS in the hands of experienced laparoscopic surgeons, especially for type I and II of Csendes classification. Definitive preoperative diagnosis and earlier management are essential.
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  • 文章类型: Case Reports
    BACKGROUND Mirizzi syndrome is biliary obstruction caused by extrinsic compression of the distal common hepatic duct by a gallstone in the adjacent cystic duct or infundibulum of the gallbladder. Post-cholecystectomy Mirizzi syndrome (PCMS) is Mirizzi syndrome in the post-surgical absence of a gallbladder. This case report of PCMS and review of the literature illustrates the diagnostic and therapeutic challenges in evaluating and managing Mirizzi syndrome. CASE REPORT A 44-year-old female with a remote history of laparoscopic cholecystectomy presented to a community teaching hospital with acute and severe upper abdominal pain and tenderness. Laboratory data revealed markedly elevated transaminases of a magnitude most often observed with hepatitis from acute viral infection, ischemia, or exposure to a hepatotoxin. PCMS was ultimately diagnosed at endoscopic retrograde cholangiopancreatography after being misdiagnosed as choledocholithiasis on magnetic resonance cholangiopancreatography. After transfer to an academic quaternary care referral hospital, the patient\'s extrahepatic biliary tree was reportedly cleared of gallstones following endoscopically-directed shock-wave lithotripsy performed at repeat -endoscopic retrograde cholangiography. CONCLUSIONS Recognizing post-cholecystectomy syndrome, in general, and PCMS, in particular, is critical when caring for patients presenting with persistent or recurrent symptoms or signs of biliary obstruction following cholecystectomy. Expediently identifying and definitively relieving the biliary obstruction, while limiting the risk of iatrogenic complication, is the priority when caring for patients with PCMS.
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