金黄色葡萄球菌产生称为小菌落变体(SCV)的特定形态变体,其负责易感个体中的持续亚临床感染,并且通常对氨基糖苷类和细胞壁活性抗生素具有抗性。由于实验室诊断的困难和对抗菌化疗的抗性,金黄色葡萄球菌的SCV感染是即将到来的问题。我们在这里报告一例儿科患者由金黄色葡萄球菌的SCV引起的感染性心内膜炎。
Staphylococcus aureus produces a particular morphological variant called small colony variant (SCV) which is responsible for persistent subclinical infections in predisposed individuals and is usually resistant to aminoglycosides and cell wall active antibiotics. Infections by SCV of S. aureus are an upcoming problem due to difficulty in laboratory diagnosis and resistance to antimicrobial chemotherapy. We here report a
case of infective endocarditis caused by SCV of Staphylococcus aureus in a pediatric patient.