最近的专家共识发现,MRS研究中的非标准报告导致可重复性差。为了解决这个问题,引入了MRSinMRS指南;然而,由于不同的术语和数据格式,收养速度很慢。为了解决这个问题,REMY,支持主要供应商格式的工具箱,被创造了。通过有效地填充MRSinMRS表中的重要字段,它提高了可重复性。即使有某些与硬件相关的限制,REMY为完成采集参数做出了重大贡献,这有利于报告。它的兼容性和用户友好的界面应该促进MRSinMRS的广泛采用,提高MRS研究的口径。
Recent expert
consensus publications have highlighted the issue of poor reproducibility in magnetic resonance spectroscopy (
MRS) studies, mainly due to the lack of standardized reporting criteria, which affects their clinical applicability. To combat this,
guidelines for minimum reporting standards (MRSinMRS) were introduced to aid journal editors and reviewers in ensuring the comprehensive documentation of essential
MRS study parameters. Despite these efforts, the implementation of MRSinMRS standards has been slow, attributed to the diverse nomenclature used by different vendors, the variety of raw
MRS data formats, and the absence of appropriate software tools for identifying and reporting necessary parameters. To overcome this obstacle, we have developed the REproducibility Made Easy (REMY) standalone toolbox. REMY software supports a range of MRS data formats from major vendors like GE (p. file), Siemens (twix, .rda, .dcm), Philips (.spar/.sdat), and Bruker (.method), facilitating easy data import and export through a user-friendly interface. REMY employs external libraries such as spec2nii and pymapVBVD to accurately read and process these diverse data formats, ensuring compatibility and ease of use for researchers in generating reproducible MRS research outputs. Users can select and import datasets, choose the appropriate vendor and data format, and then generate an MRSinMRS table, log file, and methodological documents in both Latex and PDF formats. REMY effectively populated key sections of the MRSinMRS table with data from all supported file types. Accurate generation of hardware parameters including field strength, manufacturer, and scanner software version were demonstrated. However, it could not input data for RF coil and additional hardware information due to their absence in the files. For the acquisition section, REMY accurately read and populated fields for the pulse sequence name, nominal voxel size, repetition time (TR), echo time (TE), number of acquisitions/excitations/shots, spectral width [Hz], and number of spectral points, significantly contributing to the completion of the Acquisition fields of the table. Furthermore, REMY generates a boilerplate methods text section for manuscripts.The use of REMY will facilitate more widespread adoption of the MRSinMRS checklist within the MRS community, making it easier to write and report acquisition parameters effectively.