Hepatocellular carcinoma (HCC) is a common malignancy with high mortality rates. While surgery can be curative in early-stage disease, 80% of patients cannot undergo surgical resection. Stereotactic body radiotherapy (SBRT), an emerging, non-invasive, precision treatment, has shown promising results across various stages of HCC and has thus been adopted in practice to varying degrees around the world. This article aims to review current guideline recommendations on SBRT, clinical evidence, and outcome comparisons with other local treatment modalities. Attempts are also made to compare the differences in clinical trials between Asian and Western countries.

OBJECTIVE. The objective of this article is to describe evidence-based guidelines for percutaneous minimally invasive imaging-guided thermal ablation of bone metastases. CONCLUSION. Safe and effective minimally invasive thermal ablation can be performed to achieve pain palliation, local tumor control, or cure in selected subgroups of patients with osseous metastases. Thermal protection strategies should be implemented to minimize the risk of undesired thermal injury.