Latex Hypersensitivity

乳胶超敏反应
  • 文章类型: Journal Article
    估计有85%的脊柱裂(SB)患者存活到成年期,保证特定于SB的过渡到成人医疗保健指南,以解决多样化和复杂的医疗问题,适应性,社会需要特别针对这种情况。乳胶过敏是该人群的一个重要健康问题,需要持续和终身的循证管理。本文讨论了根据2018年脊柱裂协会第四版脊柱裂患者护理指南的SBLatex过敏医疗保健指南对乳胶过敏的管理,回顾目前可以实施这种乳胶过敏指南的护理模式,并探讨了与乳胶过敏相关的SB护理的进一步相关研究课题。
    An estimated 85% of individuals with spina bifida (SB) survive into adulthood, warranting SB-specific transition to adult healthcare guidelines to address the diverse and complex medical, adaptive, and social needs particular to this condition. Latex allergy constitutes one important health concern for this population that requires ongoing and life-long evidence-based management. This article discusses management of latex allergy according to the SB Latex Allergy Healthcare Guidelines from the 2018 Spina Bifida Association\'s Fourth Edition of the Guidelines for the Care of People with Spina Bifida, reviews current care models in which such latex allergy guidelines can be implemented, and explores further relevant research topics in SB care relative to latex allergy.
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    文章类型: English Abstract
    BACKGROUND: Anaphylaxis associated with latex allergy is one of the fatal complications during anesthesia. To prevent this complication, we find out latex allergy and high-risk patients by preoperative interview and keep away not only latex allergic patients but high-risk patients from latex allergen in the operating room. In this study, we evaluated the cost-benefit efficiency of our guidelines.
    METHODS: This is a prospective observational study for six month. We classified the patients undergoing elective operation into three categories: latex allergy (group LA), high-risk of latex allergy (group LH) and control (group C), and we compared the incidence of perioperative anaphylaxis and the cost of using products without latex allergen.
    RESULTS: A total of 1.291 patients were enrolled in the analysis. Five patients (0.4%) and 206 patients (16.0%) categorized into group LA, and LH respectively. There was no patient diagnosed with anaphylaxis associated with latex allergy during the observation period. We are able to save the cost of 3.5 million yen every year by our method than using products without latex allergen for all cases.
    CONCLUSIONS: Our guidelines for prevention of perioperative anaphylaxis associated with latex allergy might be efficient from the standpoint of cost-benefit
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  • 文章类型: Consensus Development Conference
    OBJECTIVE: The Royal College of Paediatrics and Child Health (RCPCH) Science and Research Department was commissioned by the Department of Health to develop national care pathways for children with allergies; the latex allergy pathway is the seventh pathway. The pathways focus on defining the competences to improve the equity of care received by children with allergic conditions.
    METHODS: The RCPCH latex allergy pathway was developed by a multidisciplinary working group and was based on a comprehensive review of evidence. The pathway was reviewed by a broad group of stakeholders including the public and approved by the Allergy Care Pathways Project Board and the RCPCH Clinical Standards Committee.
    RESULTS: The results are presented in four parts, the evidence review, pathway mapping, external review and core knowledge documents. The evidence review highlighted the paucity of recent evidence for latex allergy in childhood. The review found that the diagnostic sensitivity of different latex extracts for skin-prick testing may differ. It also noted that health professionals should be aware of latex allergy, and care should be taken to avoid contact with latex in young infants, especially when there is a family history for latex allergy. The pathway entry points are defined by the severity at presentation.
    CONCLUSIONS: The latex allergy pathway provides a guide for training and development of services to facilitate improvements in delivery as close to the patients home as possible. The authors recommend that this pathway is implemented locally by a multidisciplinary team with a focus on creating networks between primary, secondary and tertiary care to improve services for children with allergic conditions.
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    文章类型: Case Reports
    Latex allergy is an IgE-mediated reaction to natural latex antigen. Operating room equipment frequently includes medical devices, such as surgical gloves, intravenous lines, and urinary catheters, which are made from latex or contain latex. These products can trigger an allergic reaction that can result in anaphylactic shock. Removal of natural rubber and latex-containing products from the operating room and avoidance of external and internal exposure of patients to latex antigen will prevent such allergic reactions. Updated guidelines for the safe management of latex allergy were published in 2009 by the Japanese Society of Latex Allergy. The previous guidelines regarding this topic were published in 2006. The new guidelines consist of 11 chapters that deal with background, exposure to latex antigen and development of sensitization, high-risk groups, natural rubber products, allergic reactions triggered by natural rubber products, diagnosis, latex-fruit syndrome, countermeasures and treatments in emergencies, prevention and safe management in the hospital, countermeasures in daily life, and limits for application of the guidelines. We had a case that required management according to the 2009 guidelines. A 49-year-old male doctor with a history of allergy to latex gloves was scheduled for laparoscopic cholecystectomy under general and epidural anesthesia for recurrent, acute cholecystitis. The anesthesia and operation were performed uneventfully with latex-free medical devices and machines in a latex-safe environment in the operating room under the new guidelines. Safe anesthetic management under the 2009 guidelines should be available for all operations in Japan on patients with latex allergy.
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    文章类型: Consensus Development Conference
    这份共识文件是由一个意大利工作组编写的,该工作组包括多年来参与管理医疗保健环境中与手套和乳胶有关的问题的职业卫生专业人员。本文件的目的是解决最重要的技术问题,流行病学,临床,与使用手套和乳胶有关的环境和预防问题。该小组的建议基于科学证据和实践经验,但不能被视为最终建议。这些主题需要定期修订。应考虑以下几点:手套质量似乎有了很大改善,但制造商提供的手套特征信息通常仍然不准确或不完整;现行法规规定制造商进行测试以提供产品质量证据,但它们没有指明应使用哪种分析方法,也不要求在技术数据表中报告结果。因此,制造商只需声明其产品“符合规则”;因此,购买者应要求制造公司提供详细信息并验证其可靠性。此外,规则应适应更高的质量标准;职业医生必须参与正确选择和购买防护手套;在医疗保健环境中使用手套(特别是乳胶手套)和乳胶设备应基于特定标准:程序必须说明哪种手套适合特定任务。当无法避免接触乳胶时,有必要选择具有良好生物相容性的产品(例如,无粉手套,过敏原含量低);一劳永逸的乳胶粉手套不应再在市场上出售!乳胶设备(包括手套)的标签应报告可提取的乳胶过敏原含量。应确定可提取乳胶过敏原的极限值;应鼓励使用合成橡胶手套,因为某些材料(例如,氯丁橡胶和丁腈橡胶)似乎具有与乳胶相似的物理性能和保护功效,以及良好的生物相容性;应促进更多研究以验证新合成材料的保护功效;应告知医护人员使用乳胶以外的材料的可取性和有用性;医疗保健服务不应造成额外的风险,而应强调如果尽量减少使用乳胶手套和设备对工人和患者的优势。
    This consensus document was prepared by an Italian working group including occupational health professionals involved for many years in the management of glove- and latex-related problems in health care settings. The aim of this document was to address the most significant technical, epidemiological, clinical, environmental and prevention problems related to the use of gloves and latex. The group\'s recommendations are based on scientific evidence and practical experience but they cannot be considered as final. These topics need to be periodically revised. The following points should be taken into account: glove quality seems to have improved considerably but the information on glove features provided by the manufacturers is often still inaccurate or incomplete; the regulations in force provide that the manufacturers perform tests to supply evidence for the quality of the products but they do not indicate which analytical method should be used and they do not require that the results be reported in the technical data sheets. Thus the manufacturers have only to declare that their products are \"in accordance with the rules\"; therefore, purchasers should require the manufacturing companies to supply detailed information and verify their reliability. Moreover, the rules should be adapted to higher quality standards; occupational physicians must be involved for the correct choice and purchase of protective gloves; the use of gloves (in particular latex gloves) and latex devices in health care settings should be based on specific criteria: procedures must be available stating which kind of gloves are suitable for specific tasks. When exposure to latex cannot be avoided it is necessary to choose products that have good biocompatibility (e.g., powder free-gloves with low allergen content); once and for all latex powdered gloves should no longer be commercially available! labels for latex devices (including gloves) should report the extractable latex allergen content. Limit values for extractable latex allergens should be established; the use of synthetic rubber gloves should be encouraged since some materials (e.g., neoprene and nitrile rubber) appear to have physical properties and protective efficacy similar to latex, plus good biocompatibility; more studies should be promoted to verify the protective efficacy of new synthetic materials; health care workers should be informed about the advisability and usefulness of using materials other than latex; health care services should not cause additional risks but rather highlight the advantages for workers and patients if the use of latex gloves and devices is minimized.
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