由乳酸菌引起的菌血症是罕见的,关于其临床意义的数据仅基于病例报告和有限数量的研究,往往难以解释。乳杆菌属是口腔的共生定植体,胃肠道和泌尿生殖道。其作为病原体的重要性经常被忽视。这些感染的诊断需要医生和微生物学家之间的相互关系来排除污染风险。大多数患有乳酸杆菌菌血症的患者是免疫抑制的或有症状的菌血症伴随合并症的风险增加的患者。用广谱抗生素治疗,并有留置静脉导管。与乳酸菌菌血症相关的危险因素包括宿主防御能力受损和严重的基础疾病。以及先前的手术和长期的抗生素治疗对乳酸杆菌无效。我们描述了一个女人的不寻常案例,关于慢性血液透析治疗,因干酪乳杆菌引起的败血症,并回顾文献。
Bacteremia caused by Lactobacillus is rare, data on its clinical significance are based only on case reports and a limited number of studies, often difficult to interpret. Lactobacillus species is a commensal colonizer of the mouth, gastrointestinal and genitourinary tract. Its significance as a pathogen is overlooked frequently. The diagnosis of these infections requires a mutual relationship between the physician and the microbiologist to rule out contamination risk. Most patients with Lactobacillus bacteremia are immunosuppressed or patients at increased risk of symptomatic bacteremia with comorbidities, treated with broad-spectrum antibiotics and have indwelling venous catheters. Risk factors related to Lactobacillus bacteremia include impaired host defenses and severe underlying diseases, as well as prior surgery and prolonged antibiotic therapy ineffective for lactobacilli. We describe an unusual case of a woman, on chronic hemodialysis treatment, with a sepsis due to Lactobacillus casei and
review the literature.